Wednesday December 12, 2018

Ultrasound, Blood Test Together May Boost Liver Cancer Detection

Cancer screening guidelines for patients with cirrhosis vary, with some guidelines calling for just imaging and other guidelines calling for both imaging and AFP measurement

0
//
AFP is a plasma protein that is produced in abundance by the liver cells in the foetus. In adults, AFP levels are normally low, but liver cancer can cause AFP levels to rise. Pixabay
AFP is a plasma protein that is produced in abundance by the liver cells in the foetus. In adults, AFP levels are normally low, but liver cancer can cause AFP levels to rise. Pixabay
Republish
Reprint

Earlier detection is important to improving survival of patients with liver cancer, and combining an ultrasound imaging with a blood test can help achieve that, say researchers, including one of Indian-origin.

Using ultrasound and a blood test for high alpha-fetoprotein (AFP) levels together improves detection of early-stage cancer significantly, said the study published in the journal Gastroenterology.

ALSO READ: All Women Can Be Screened For Cancer!

“Liver cancer screening in patients with chronic liver disease has traditionally been performed using an abdominal ultrasound. While ultrasound is readily available and noninvasive, it misses many cancers when they are small,” said Amit Singal, associate professor at the University of Texas Southwestern Medical Centre.

Risk factors for this cancer — also known as hepatocellular carcinoma (HCC) — include hepatitis C infection, chronic heavy alcohol consumption, and nonalcoholic fatty liver disease related to diabetes and obesity.

Symptoms can include upper abdominal pain or swelling, loss of weight or appetite, white chalky stools, and general fatigue, the researchers said. Pixabay
Symptoms can include upper abdominal pain or swelling, loss of weight or appetite, white chalky stools, and general fatigue, the researchers said. Pixabay

“Our study found that adding the blood biomarker alpha-fetoprotein increased detection of early-stage hepatocellular carcinoma from 45 percent with ultrasound alone to 63 percent using the two tests in combination,” Singal said.

ALSO READ: Research Yields Possible Blood Test for Cancer

“Our results support a change in clinical practice and the routine use of ultrasound and biomarkers together for liver cancer screening,” Singal said.

The results were based on a meta-analysis of 32 previous studies. Meta-analysis refers to a technique of combining the results of multiple scientific studies.

Click here for reuse options!
Copyright 2018 NewsGram

Next Story

World’s Smallest Wearable Can Help in Preventing Skin Cancer

It also demonstrated the ability to measure white light exposure for seasonal depression, a mood disorder characterised by depression that occurs at the same time every year

0
cancer
World's smallest device to prevent skin cancer, mood disorder risk. Pixabay

Scientists have developed the world’s smallest wearable, battery-free device that can warn people of overexposure to ultraviolet rays (UV) — a leading factor for developing skin cancer.

Currently, people do not know how much UV light they are actually getting. The rugged and waterproof device interacts wirelessly with the phone and helps maintain an awareness and for skin cancer survivors.

Smaller than an M&M (colourful button-shaped chocolates) and thinner than a credit card, the device can optimise treatment of neonatal jaundice, skin diseases, seasonal affective disorder and reduce risk of sunburns and skin cancer.

Users can glue the device on to their hats, clip it to sunglasses or stick it on their nail and can simultaneously record up to three separate wavelengths of light.

It is always on yet never needs to be recharged.

“There is a critical need for technologies that can accurately measure and promote safe UV exposure at a personalised level in natural environments,” said Steve Xu, from Northwestern University in the US.

Cancer
Cancer Ribbon. Pixabay

“We hope people with information about their UV exposure will develop healthier habits when out in the sun,” said Xu.

There are no switches or interfaces to wear out, and it is completely sealed in a thin layer of transparent plastic, the researchers stated, in the paper published in the journal Science Translational Medicine.

Participants who mounted device on themselves recorded multiple forms of light exposure during outdoor activities, even in the water.

Also Read- First NASA Probe to Return Asteroid Sample Reaches Destination

The findings showed that it monitored therapeutic UV light in clinical phototherapy booths for psoriasis and atopic dermatitis (immune diseases) as well as blue light phototherapy for newborns with jaundice in the neonatal intensive care unit.

It also demonstrated the ability to measure white light exposure for seasonal depression, a mood disorder characterised by depression that occurs at the same time every year. (IANS)