Tuesday April 7, 2020

Here’s Why Losing Sleep For Only One Night May Cause Alzheimer’s Disease

Previous studies of older adults have suggested that sleep deprivation can increase the level of tau in the cerebral spinal fluid

0
//
Even
Even in young, healthy individuals, missing one night of sleep increases the level of tau in blood suggesting that over time, such sleep deprivation could possibly have detrimental effects. Pixabay

 Losing just one night of sleep fuels brain proteins linked to the development of Alzheimer’s disease, a new research warns.

The study, published in the journal Neurology, found that when young, healthy men were deprived of just one night of sleep, they had higher levels of tau, a biomarker for Alzheimer’s disease, in their blood than when they had a full, uninterrupted night of rest.

Tau is a protein found in neurons that can form into tangles. These accumulate in the brains of people with Alzheimer’s disease. It can start to develop in the brain decades before symptoms of the disease appear. Previous studies of older adults have suggested that sleep deprivation can increase the level of tau in the cerebral spinal fluid.

“Our exploratory study shows that even in young, healthy individuals, missing one night of sleep increases the level of tau in blood suggesting that over time, such sleep deprivation could possibly have detrimental effects,” said study author Jonathan Cedernaes, from Uppsala University in Sweden. The study involved 15 healthy, normal-weight men with an average age of 22. They all reported regularly getting seven to nine hours of quality sleep per night.

There were two phases to the study. For each phase, the men were observed under a strict meal and activity schedule in a sleep clinic for two days and nights. Blood samples were taken in the evening and again in the morning. For one phase, participants were allowed to get a good night of sleep both nights.

For the other phase, participants were allowed to get a good night of sleep the first night followed by a second night of sleep deprivation. During sleep deprivation, lights were kept on while participants sat up in bed playing games, watching movies or talking.

Researchers found that the men had an average 17 per cent increase in tau levels in their blood after a night of sleep deprivation compared to an average two per cent increase in tau levels after a good night of sleep.

brain
Losing just one night of sleep fuels brain proteins linked to the development of Alzheimer’s disease, a new research warns. Pixabay

Researchers also looked at four other biomarkers associated with Alzheimer’s but there were no changes in levels between a good night of sleep and one night of no sleep. “It’s important to note that while higher levels of tau in the brain are not good, in the context of sleep loss we do not know what higher levels of tau in blood represent,” said Cedernaes.

ALSO READ: Apple Asks Employees in U.S. To Work From Home Amidst Coronavirus Outbreak

According to the researchers, when neurons are active, production of tau in the brain is increased. Higher levels in the blood may reflect that these tau proteins are being cleared from the brain or they may reflect elevated tau levels in the brain. (IANS)

Next Story

Life in Wuhan After Coronavirus Outbreak

Vendors Return in Wuhan as China Prepares Virus Memorial

0
Wuhan
Authorities are easing controls in Wuhan that kept 11 million people at home for two months. Pixabay

Sidewalk vendors wearing face masks and gloves sold pork, tomatoes, carrots and other vegetables to shoppers Friday in the Chinese city where the coronavirus pandemic began, as workers prepared for a national memorial this weekend for health workers and others who died in the outbreak.

Authorities are easing controls that kept Wuhan’s 11 million people at home for two months, but many shops are still closed. Shoppers and sellers in the Minyi neighborhood on the city’s southwest side had to do their business over high yellow barriers, as access to the community is still controlled.

“I don’t feel safe going to a supermarket,” said Zhan Zhongwu, who wore two layers of masks and was buying pork for his wife and grandchild. “There are too many people,” he said. “Many infections happened in the supermarket.”

Residents have been relying on online groceries and government-organized food deliveries after most access to the city was suspended Jan. 23 and restaurants, shops and other businesses shut down.

Please follow NewsGram on Twitter to get updates on the latest news

Wuhan and the rest of China are preparing for a nationwide three minutes of silence on Saturday in honor of the 3,322 people who officially died of the virus, including doctors, nurses and other health workers who have been declared martyrs.

They include Li Wenliang, an eye doctor in Wuhan who was reprimanded in December for warning about the virus and later died of the disease. He became a symbol of public anger at the ruling Communist Party for suppressing information about the coronavirus, possibly worsening its spread, before it took action in late January.

The party rescinded Li’s reprimand and declared him a hero as part of a propaganda effort aimed at deflecting criticism of the official response.

On Saturday, national flags will be lowered to half-staff at 10 a.m. while air raid sirens and the horns of cars, trains and ships will “wail in grief,” the official Xinhua News Agency said.

Please follow NewsGram on Facebook to get updates on the latest news

People have been told to avoid cemeteries on Saturday, the start of a three-day holiday when families traditionally tend the graves of ancestors.

Wuhan
Residents wearing masks to protect against the spread of the coronavirus line up to enter a supermarket in Wuhan in central China’s Hubei province. VOA

While the United States and other governments tighten controls and shut down businesses, Chinese leaders are trying to revive the world’s second-largest economy after declaring victory over the outbreak.

Still, local authorities have orders to prevent new infections as millions of people stream back to work in factories, offices and shops. Passengers on planes, trains, subways and buses are checked for fever and employers have orders to disinfect workplaces regularly.

Vegetable vendor Xie Lianning said she picked up supplies at a wholesale market at 5 a.m. and drove to Minyi. She was checked for fever at the neighborhood entrance.

Please follow NewsGram on Instagram to get updates on the latest news

Xie set up shop on a sidewalk in front of closed shops that were covered by roll-down metal doors. The block was surrounded by the head-high yellow barriers installed to keep residents inside during the quarantine.

“Our business is not bad. Here is definitely better than indoors,” said Xie. “Nobody wanted to go inside. People are willing to buy things outside.”

Also Read- The Effects of Social Distancing and Isolation

Wuhan accounts for three-quarters of China’s virus deaths but has reported no new cases for a week. Despite that, controls requiring official permission to enter or leave the city are to stay in place through Tuesday.

Xie said she still was worried about the virus but had to get back to work.
“We have no choice,” she said. “There are old and young in my family living with us. We have a heavy financial burden.”  (VOA)