Thursday, July 2, 2020
Home Life Style Health & Fitness Consume Low-Fat Diet To Decrease Colon Cancer Risk

Consume Low-Fat Diet To Decrease Colon Cancer Risk

High-fat diet may increase risk of developing colon cancer

Two genes that appear to help stem cells in the intestine burn dietary fat may play a role in colon cancer, according to a new study.

The study, published in the journal Gastroenterology, described a new connection between the way cells consume fat and how genes regulate stem cell behaviour in the intestines of mice.

“This is important because scientists have shown that when there’s too much dietary fat in the intestine, stem cell numbers increase, boosting susceptibility to colon cancer,” said senior author Michael Verzi, associate professor in the Department of Genetics at Rutgers University-New Brunswick.

People naturally lose millions of intestinal cells daily, much like they lose skin cells.

Dietary fat
When there’s too much dietary fat in the intestine, stem cell numbers increase. Pixabay

Intestinal stem cells undergo constant renewal and fuel the continuous turnover of the lining of the intestine, but altered stem cell functions can lead to colon cancer.

Recent studies have shown that intestinal stem cells can increase in animals on a high fat “Western” diet, potentially explaining an elevated cancer risk from such a diet.

The team recently discovered that two genes (HNF4A and HNF4G) work together to promote the proper function of the intestinal lining.

Also Read- Researchers Associate Obesity With Brain Damage

In the new study, they found that mice lost intestinal stem cells when these genes were inactivated, confirming their importance. Scientists believe that the genes help stem cells burn fat, providing them energy.

Going forward, the researchers hope to further investigate whether the two genes alter stem cell numbers and cancer risk during a high fat diet, said Verzi, who is also a member of the Rutgers Center for Lipid Research. (IANS)

STAY CONNECTED

19,004FansLike
362FollowersFollow
1,779FollowersFollow

Most Popular

Covid-19 Conspiracy Theories Amplified by Social Media

People who get most of their news from social media like Facebook and YouTube are much more likely to believe conspiracy theories about the...

COVID-19 Accelerating Worldwide : WHO

The World Health Organization says 60 percent of the world’s 10 million COVID-19 cases since December came in the month of June – a...

Doctors Talk About Challenges they Face During the Pandemic

The year 2020 belongs to doctors and the healthcare workers who are risking their lives to fight the lethal, invisible virus Covid-19. While India...

Travel Virtually To These Places Amidst Lockdown

Travel is one of the most rewarding and enriching adventures one can indulge in. Every year, travel enthusiasts from across the world plan their...

Sustainable Kitchen Herb Gardening and it’s Benefits

Your small choice of starting a kitchen herb garden or nurturing the gardening habit can lead you to join the fight against global warming....

Covid-19 Infected Patients’ Blood Can Tell Severity Of Illness

Clinicians can examine Covid-19 patients' blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a...

While Covid-19 Continues, Don’t Forget Virus with Pandemic Potential

Don't panic, but there is another virus out there that could cause a pandemic. This one is an influenza strain circulating in pigs and...

SARS-CoV-2 Can Directly Infect Heart Cells of Covid-19 Patients

A team of US scientists, led by an Indian-origin researcher revealed that SARS-CoV-2 (coronavirus), the virus behind Covid-19, can infect heart cells in a...

Recent Comments