Never miss a story

Get subscribed to our newsletter


×
There is a significant connection between obesity and Pancreatic Cancer. Lifetime Stock

The sound of the word ‘Cancer is enough to scare anyone because there is no definite cure for it. Pancreatic cancer is one of those cancers in which the overall survival is very bleak as cases are often less sensitive to chemotherapy and radiotherapy. Dr Pradeep Jain, GI Oncosurgery, Medical Oncology, Fortis Hospital, Shalimar Bagh informs you about the connection between obesity and Pancreatic Cancer.

The best method to decrease the mortality (death rate) of these cancers is to either catch them early or prevent them happening. In view of non-availability of any screening test and limitation of diagnostic test, it is almost impossible to catch them very early. As dietary modification has been known for a long time to prevent cancer, it is likely to work in case of pancreatic cancer also.



Dietary modification has been known to cut down the risk of developing pancreatic cancer. Lifetime Stock

Pancreatic cancer is associated with obesity and fat consumption as suggested in many epidemiological studies. Consumption of fat has been linked to pancreatic cancer not only directly but also by causing obesity. In obesity there is a general increase in inflammatory conditions in the body which leads to release of some chemicals (cytokines) which have important role in creation of pancreatic cancer.

Fat consumption (mainly saturated fats) have been shown to increase cancer of the pancreas by many observational studies in last 2 decades. In fact a study published (which comprised of more than half million US adults) in journal of the National Cancer Institute in 2009 demonstrated a positive association between dietary intake of total fat, particularly from animal sources. When people taking highest of fat compared to people taking lowest of fat, they are 23 per cent more likely to be diagnosed with pancreatic cancer (the effect was more profound when intake of saturated fat was more).

It is very difficult to comment how does fat consumption lead to pancreatic cancer, but it is likely that fat stimulates the release of an important hormone CCK (Cholecystokinin) for biliary and pancreatic secretion. And this hormone is an important instrument in the growth of pancreatic cancer cells.

In fact, in an experimental study, the antagonist of CCK, Proglumide has shown to decrease the growth of cancer cells and decrease metastasis (spread) potential of cancer.


Pancreatic cancer is associated with obesity and fat consumption. Lifetime Stock

Now this leads to an important question whether with diet modification (by reducing content of fat) is it possible to decrease the chances of pancreatic cancer? A recent study published in Nov 2017 issue of AICR’S cancer research update) have found that older women who are overweight or obese had lowered the risk of getting pancreatic cancer by following a low fat diet plan.

Some were arranged to eat less fat and more vegetables, fruits and grains (the intervention group) other followed their normal diet (the comparison group). After 15 years of follow up, 92 cases of pancreatic cancer were identified in the intervention group and 165 in the comparison group. This translates to a rate of 35 cases per 100,000 in the intervention group and 41 per 100,000 in the comparison group.

Low fat diet was particularly effective in reducing cancer risk in over weight and obese post-menopausal woman. A low fat diet was not found to lower the disease risk for women whose weight was normal.

Also Read- Here’s How Sugar Relates to Cancer

Though these evidences support that high fat consumption may increase the chances of pancreatic cancer and by reducing the fat consumption the incidence of cancer may decrease, but these cannot be considered as very strong evidence to support a ‘cause and effect’. But this can be considered at least a caution to decrease fat (particularly animal fat) consumption in diet.

Foods that are sources of saturated or trans fats are butter, margarine (stick), coconut oil, palm oil, vegetable oil and hydrogenated oil. We should motivate the general public to consume more of fibre and exercise and reduce saturated fat content from diet. (IANS)


Popular

wikimedia commons

Recently, Tom and Jerry was made into a live action film

Every child who grew up in the 90s and the early 00s has certainly grown up around Tom and Jerry, the adorable, infamous cat-chases-mouse cartoon. The idea of naughtiness and playing mischief had the standards that this particular series set for children and defined how much wreckage was funny enough.

The show's creators, William Hanna and Joseph Barbera initially named their characters Jasper and Jinx. They did not plan for the fame that Tom and Jerry brought them when they released a movie by the name of "Puss Gets the Boot". This movie featured a certain cat and mouse who were a notorious pair, named Jasper and Jinx. When the movie became a hit, the names of the characters were changed and the show shot to fame.

Keep Reading Show less
Photo by Unsplash

Indians Rarely Make Time For Arts And Culture, Says Survey

One of India's leading private museums, the Museum of Art & Photography (MAP) Bengaluru, has released new primary research conducted by the ReReeti Foundation, on audience behaviour in India's cultural sector. While more than half of the respondents thought the arts and culture are essential, they rarely manage to make time for it. The majority (60.6 per cent), mostly young people under 30, felt Indian museums could present more engaging content, and most perceived culture as anthropological/ sociological. Of the diverse categories included, music emerged as the most popular cultural activity.

The report is based on a survey of 500 people, which included school and college students, professionals across sectors, homemakers and senior citizens. The first initiative of its kind in the cultural space, the report shares valuable insights into the behaviour and expectations of Indian audiences engaging with a broad range of cultural activities. As part of MAP's mission to foster meaningful connections between communities and the cultural sector globally, which includes its innovative digital programme Museums Without Borders, the report shares a wealth of insights that can help museums across the country understand their audiences better. As much as 60.6 per cent said Indian museums are not experimental enough, and can do more to create engaging content that is also relevant to surrounding communities.As much as 60.6 per cent said Indian museums are not experimental enough, and can do more to create engaging content that is also relevant to surrounding communities.

Keep Reading Show less
Photo by alexey turenkov on Unsplash

What is the best way to save Goa from deforestation?

What is the best way to save Goa from deforestation?

Drinking feni, may well be the answer, says the secretary of the Goa Cashew Feni Distillers and Bottlers Association Hansel Vaz, who on Thursday said, that sipping the state's unique alcoholic drink and making it popular would directly aid the greening of Goa's hills and other barren landscapes.

"To get more cashews, we need to plant more trees. I always say, by drinking feni you will save Goa, because we will be planting more cashew trees and we will have greener hills. The beauty of cashew is you do not need fertile land. You can grow it on a hill which can provide no nutrition. We will be able to grow more trees, if we can sell feni properly," Vaz said. Vaz's comments come at a time when the hillsides of the coastal state have witnessed significant deforestation for real estate development and for infrastructure projects. Feni is manufactured by fermenting and double distilling juice from the cashew apple.

2 glasses of a white drink Best way to keep Goa green is to grab yourself a glass of feni. | IANS

Keep reading... Show less