Saturday January 25, 2020

Researchers Develop Machine Keeping Human Livers Alive For a Week Outside Body

The next step will be to use these organs for transplantation. The proposed technology opens a large avenue for many applications offering a new life for many patients with end stage liver disease or cancer

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The study shows that six of ten perfused poor-quality human livers, declined for transplantation by all centres in Europe, recovered to full function within one week of perfusion on the machine. Pixabay

Researchers have developed a machine that repairs injured human livers and keeps them alive outside the body for one week.

According to the study, published in the journal Nature Biotechnology, this breakthrough may increase the number of available organs for transplantation saving many lives of patients with severe liver diseases or cancer.

“The success of this unique perfusion system — developed over a four-year period by a group of surgeons, biologists and engineers — paves the way for many new applications in transplantation and cancer medicine helping patients with no liver grafts available,” said study researcher Pierre-Alain Clavi from the University Hospital Zurich in Switzerland.

Until now, livers could be stored safely outside the body for only a few hours. With the novel perfusion technology, livers — and even injured livers — can now be kept alive outside of the body for an entire week.

This is a major breakthrough in the transplantation medicine, which may increase the number of available organs for transplantation and save many lives of patients suffering from severe liver diseases or a variety of cancers.

Injured cadaveric livers, initially not suitable for use in transplantation, may regain full function while perfused in the new machine for several days.

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According to the study, published in the journal Nature Biotechnology, this breakthrough may increase the number of available organs for transplantation saving many lives of patients with severe liver diseases or cancer. Pixabay

According to the researchers, the basis for this technology is a complex perfusion system, mimicking most core body functions close to physiology.

The Liver4Life project was developed under the umbrella of Wyss Zurich institute, which brought together the highly specialised technical and biomedical knowledge of experts from the University Hospital Zurich.

“The biggest challenge in the initial phase of our project was to find a common language that would allow communication between the clinicians and engineers,” said researcher Philipp Rudolf von Rohr.

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The study shows that six of ten perfused poor-quality human livers, declined for transplantation by all centres in Europe, recovered to full function within one week of perfusion on the machine.

The next step will be to use these organs for transplantation. The proposed technology opens a large avenue for many applications offering a new life for many patients with end stage liver disease or cancer. (IANS)

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India Becomes the Second Largest Smartphone Market After China: Report

India surpasses US to become 2nd largest smartphone market

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The Indian smartphone market surpassed the US for the first time on an annual level. Pixabay

New Delhi: Riding on Chinese brands, the India smartphone market surpassed the US for the first time on an annual level and this is the latest science and technology news, becoming the second-largest smartphone market after China globally — reaching 158 million shipments in the calender year 2019 with 7 per cent (YoY) growth, a report from Counterpoint Research said on Friday.

While Xiaomi continued to be the top player with 28 per cent market share in the calendar year 2019, Samsung was second with 21 per cent and Vivo at 16 per cent market share, said Counterpoint’s ‘Market Monitor’ service.

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India has now become the second-largest smartphone market after China globally. Pixabay

“Although the rate of growth for smartphone market hit single digit for the first time ever on an annual basis, India is underpenetrated relative to many other markets with 4G penetration in terms of subscribers being around 55 per cent,” said Tarun Pathak, Associate Director, Counterpoint.

“Chinese brands share hit a record 72 per cent for the year 2019 as compared to 60 per cent share a year ago.

“This year, we have seen all major Chinese players expanding their footprint in offline and online channels to gain market share. For instance, Xiaomi, realme, and OnePlus have increased their offline points of sale while brands like Vivo have expanded their online reach with Z and U series,” said Anshika Jain, Research Analyst at Counterpoint.

Over the past four years, Xiaomi, Vivo, and OnePlus have grown 15 times, 24 times and 18 per cent, respectively.

“This highlights that OEMs are mature enough to capture next wave of growth and expand their operations in India,” Jain added.

Smartphone
Although the rate of growth for smartphone market hit single digit for the first time ever on an annual basis, India is underpenetrated relative to many other markets with 4G penetration in terms of subscribers being around 55 per cent. Pixabay

Samsung shipments remained almost flat (YoY) while it has shown a 5 per cent (YoY) decline in 2019.

“This is for the first time Samsung transitioned to a completely new portfolio targeting different channels (offline with A series and online with M series). However, it needs to double down its efforts to keep the momentum going,” the report noted.

While the smartphone market registered YoY growth, the feature phone market witnessed a steep decline of nearly 42 per cent YoY in 2019 and 38 per cent (YoY) in Q4 2019.

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“This is due to slowdown in the new shipments from Reliance Jio. However, the players such as itel, Lava, Nokia and Micromax registered positive annual
growth despite the overall segment declined showing the untapped potential of the market,” said the report.

In fact, itel emerged as the number one feature phone brand in Q4 2019, followed by Samsung and Lava. (IANS)