Friday February 28, 2020

Males Have Higher Risk of Suffering from Cancer: Study

Researchers explain why cancer risk is higher in males

0
//
Cancer
DNA differences between men and women may explain why cancer risk is higher in males. Pixabay

DNA differences between men and women may explain why cancer risk is higher in males, according to a new study.

In findings published in the Journal of the National Cancer Institute, researchers have reported that loss of function in certain genes of the sex-determining Y chromosome, which is present only in men, may cause them to have an elevated risk for cancer.

Using data from 9,000 individuals, the researchers studied Y-chromosome gene function in patients with various types of cancer. The findings showed that cancer risk increases with loss of function of six key Y-chromosome genes in various types of cells.

“Recent studies have shown that complete loss of the Y chromosome, which is essential to foetal sex differentiation, occurs, with aging, in the cells of some men,” said study author Juan Ramon Gonzalez from Barcelona Institute for Global Health in Spain.

Cancer DNA
Suppression of the Y chromosome can occur as a result of loss of function in the chromosome. Pixabay

“Although the loss of the Y chromosome has previously been associated with higher incidence of cancer, the causes of this association are poorly understood,” Gonzalez added.

These six Y-chromosome genes are involved in cell-cycle regulation, the failure of which can lead to tumour development.

According to the study, understanding the biological differences between men and women in cancer is crucial for the development of personalised lines of treatment and prevention.

“Men are not only at higher risk of cancer than women, they also face a worse prognosis. In fact, these differences partially account for the lower life expectancy of men,” Gonzalez added.

According to the researchers, although men may be more exposed to carcinogens due to the type of work they do and at higher risk because they are less likely to consult a doctor, the study has shown that there are also biological factors that increase cancer risk among men.

“In fact, it seems that one of these factors can be found in the Y chromosome, the very essence of maleness,” said study lead author Alejandro Caceres.

Also Read- Know About the Health Benefits of Green Tea

Suppression of the Y chromosome can occur as a result of loss of function in the chromosome, which would explain previous findings, or as a result of other mechanisms mediated by the chemical (epigenetic) inactivation of the same regions, the research said.

“Certain environmental exposures, for example to tobacco or other harmful substances, could affect chromosome function and lead to epigenetic modifications,” Gonzalez said. (IANS)

Next Story

Top 3 Travel Destinations in Asia For Solo Women Travellers

Unique Asian destinations for solo female travellers

0
Women travel
While the most popular destinations for solo female travellers are in Europe, there are quite a number of destinations in Asia that are especially ideal for women travellers given that you're properly prepared. Pixabay

In recent years, the number of women embarking on solo adventures has skyrocketed — a fact corroborated by the data of many travel companies — and in many cases, to less-frequented destinations. Indeed, navigating new cities and learning to handle hustlers without a companion or ‘safety in numbers’ can be incredibly empowering for women. Right off the bat, travelling alone is the ultimate confidence boost and the freedom to plan ones own travel itinerary without having to accommodate anyone else is liberating.

For first-timers, travelling alone can seem like a daunting prospect, but with some research, planning and common sense, it could become a life-changing experience. While the most popular destinations for solo female travellers are in Europe, there are quite a number of destinations in Asia that are especially ideal for women travellers given that you’re properly prepared. Here are top picks by ONYX Hospitality Group of unique destinations in Asia for women to explore solo.

Women travel
Malaysia is a very safe travel destination for women. Pixabay

Colombo and Kandy, Sri Lanka

Spend a few days in Colombo, a busy and vibrant port city, to experience the laid-back charm of the historical era combined with the liveliness of a modern city. Those looking for a more peaceful environment can head for Kandy. Once the capital of the ancient kings, Kandy remains the country’s most significant cultural and religious centre. Visit the tea plantations, pray at the Temple of the Sacred Tooth relic and go trekking into the misty hills where you can take a deep breath and reconnect with yourself and nature.

Phuket, Thailand

Famously dubbed as the island of contrasts, Phuket is a great destination for solo female travellers looking to have the best of both worlds. From relaxing, feet-in-the-sand detox and laid-back beachside cafes, to adrenaline-fuelled activities and vibrant nightlife, this tropical paradise has it all. Start by exploring the spectacular stretch of gorgeous beaches along the island’s West coast where time goes slow and sunshine seems to last forever, before switching it up with a tuk tuk ride to the east coast for some cafe-hopping and bar-crawling with the local crowds.

Travelling around Phuket is surprisingly easy. You can either hop on a tuk tuk, grab a taxi or even rent a motorbike and helmet and zoom down the hills with the view of the turquoise sea stretching out before you.

Women travel
Phuket is a great destination for solo women travellers looking to have the best of both worlds. Pixabay

Possibly one of the most beautiful beaches in Phuket, Kata is a paradise waiting for people to visit and fall in love. White sand, blue sea and endless activities are just a few of the things that make Kata beach so special. Meanwhile, a walk through the local area can add a lively touch of Thai culture to any holiday.

Penang, Malaysia

Known as the Pearl of the Orient, Penang is a truly fascinating destination with its colourful five-foot-ways, mouth-watering street food, lush hiking trails and sandy beaches. Declared a UNESCO world cultural heritage site, George Town, the island’s cultural and urban hub, is brimming with architectural marvels from the British colonial period, timeworn shophouses, modern cafes and temples. Feast on local delicacies such as Assam Laksa or Char Kway Teow from hawker stands before walking the guilt off while exploring the world-famous mural trails.

Also Read- 4 Superfoods to Balance Out Your Hormones

Feeling overwhelmed by the paddling trishaws and fuming fragrant? One only needs to take a short bus ride away from town for a stroll along the beaches, a visit to the Tropical Spice Garden or the picturesque Penang Hill. (IANS)