Tuesday July 23, 2019

Managing Weight During Pregnancy May Affect Child’s Bone Health

The team analysed prospective data from 2,167 mother-child pairs

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Pregnancy, autism
Pregnancy after breast cancer does not increase a woman's risk of a relapse. Pixabay

There is no benefit for children’s bone mass if women gain weight during pregnancy, says a new study.

And this applies to both normal and overweight women prior to pregnancy, says Teresa Monjardino, lead author from the Universidade do Porto in Portugal.

Weight management strategies during pregnancy reduce child cardiometabolic risk such as diabetes and heart disease.

However, because maternal weight has an overall positive correlation with a child’s bone mass, pregnancy weight management could adversely affect child bone health, said the researchers.

The study, published in the Journal of Bone and Mineral Research, showed that in under and normal weight mothers, weight gain during pregnancy was associated with slightly increased bone mass at 7 years of age in children.

Pregnancy, air pollution
Weight management strategies during pregnancy reduce child cardiometabolic risk such as diabetes and heart disease. Pixabay

On the other hand, in the case of overweight or obese mothers, no beneficial effect of weight gain on bone mass was observed.

“Until recently, it was a widely held scientific belief that any weight gain from the mother during pregnancy would have a beneficial effect on children’s bone mass,” said Monjardino.

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“Our study results corroborate that there is no benefit in gaining weight above the US Institute of Medicine recommendations for pregnancy weight gain for children’s bone mass, in both normal and overweight women prior to pregnancy,” added Monjardino.

The team analysed prospective data from 2,167 mother-child pairs. (IANS)

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Consuming High- Fibre Diet may Reduce Risk of Preeclampsia During Pregnancy

Pregnancy outcomes and infant immunity are linked to gut bacteria

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The mother's gut bacteria and diet appear to be crucial to promoting healthy pregnancy. Pixabay

Ladies, please take note. Consuming a high-fibre diet may reduce the risk of preeclampsia during pregnancy, researchers have found.

“Simple recommendation to ‘eat real food, mostly plants and not too much’ might be the most effective primary prevention strategy for some of the most serious conditions of our time.

“The mother’s gut bacteria and diet appear to be crucial to promoting healthy pregnancy,” said study lead author Ralph Nanan, Professor at the University of Sydney.

The study, published in the journal Nature Communications, showed that pregnancy outcomes and infant immunity are linked to gut bacteria.

Fibre, Diet, Pregnancy
Ladies, please take note. Pixabay

Plant-based fibre is broken down in the gut by bacteria into factors that influence the immune system. The research team investigated the role of these metabolic products of gut bacteria during pregnancy.

The researchers found that in humans, reduced levels of acetate, which is mainly produced by fibre fermentation in the gut, is associated with the common and serious pregnancy-related condition preeclampsia.

Preeclampsia occurs in up to 10 per cent of pregnancies and is characterized by high blood pressure, protein in the urine and severe swelling in the mother’s body.

It also interferes with the child’s immune development whilst in the womb, with some evidence suggesting a link to higher rates of allergies and autoimmune diseases later in life.

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The study found that preeclampsia affected the development of an important foetal immune organ – the thymus – which sits just behind the breastbone.

Foetuses in preeclamptic pregnancies were found to have a much smaller thymus than children from healthy pregnancies.

The cells the thymus normally generates — called ‘T’ cells, and specifically those associated with the prevention of allergies and autoimmune conditions such as diabetes — also remained lower in infants after preeclampsia, even four years after delivery.

Fiber, Diet, Pregnancy
Consuming a high-fibre diet may reduce the risk of preeclampsia during pregnancy, researchers have found. Pixabay

The mechanisms of acetate on the developing foetal immune system were further examined in separate experiments involving mice that showed acetate was central in driving foetal thymus and ‘T’ cell development.

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The results showed that promoting specific metabolic products of gut bacteria during pregnancy might be an effective way to maintain a healthy pregnancy and to prevent allergies and autoimmune conditions later in life. (IANS)