Wednesday September 19, 2018

Marijuana Considered Safe to Cure Epilepsy in Kids

While the study's authors said the results were significant, they stressed that the purpose of this study was about safety not efficacy

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Marijuana safe to treat epilepsy in kids: Study. Pixabay
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Consuming a marijuana-based drug may be safe in treating children with severe epilepsy, results of a clinical trial has showed.

Following treatment with cannabidiol — a non-psychoactive compound found in marijuana — about one in five children were described as much or very much improved from their baseline, while around half reported none, or a very slight improvement, Xinhua news agency reported.

While the trial was conducted on a small group of children with severe epilepsy, it showed that the drug had a manageable side effect profile, but only showed extensive symptom relief for a brief number of patients.

The trial “involved the sickest children with epilepsy — children who are having seizures many times per day, who have been recently hospitalized for their epilepsy, and have failed on average about nine anti-epilepsy drugs before,” said lead author John Lawson, paediatric neurologist at Sydney’s Children’s Hospital.

“The main aim of the study was about safety. We found that there were a few safety concerns but overall those safety issues were very manageable and the drug overall was very safe for the majority,” he added.

Marijuana
Marijuana leaves. Pixabay

The study was published in the Medical Journal of Australia.

Although legally cannabis must be prescribed by a doctor, recent reports of cannabis derivatives being successful in treating children with epilepsy have led to a number of parents of sick children sourcing their own medical marijuana.

While the study’s authors said the results were significant, they stressed that the purpose of this study was about safety not efficacy.

Also Read: Oldest Known Rocks Evolved on Earth Are Result of Asteroids, Research Reveals

The US Food and Drug Administration had recently approved Epidiolex (cannabidiol) [CBD] oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy — Lennox-Gastaut syndrome and Dravet syndrome — in patients two years of age and older. (IANS)

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Exposure to Certain Disinfectants Can Cause Obesity in Kids: Research

The use of eco-friendly products may be linked to healthier overall maternal lifestyles and eating habits.

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Disinfectants
How common household cleaners could make kids overweight. Flickr

Early life exposure to certain disinfectants used at home could be making children overweight by altering the composition of their gut bacteria, suggests new research.

Babies living in households that used eco-friendly cleaners had different microbiota and were less likely to be overweight as toddlers, showed the findings published in CMAJ (Canadian Medical Association Journal).

For the study, the researchers analysed the gut flora of 757 infants from the general population at age 3-4 months and weight at ages 1 and 3 years, looking at exposure to disinfectants, detergents and eco-friendly products used in the home.

Disinfectants
Mother’s Lifestyle Choices Linked to Obesity Risk in Adolescents. Pixabay

The researchers looked at data from the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort on microbes in infant fecal matter. They used World Health Organization growth charts for body mass index (BMI) scores.

Associations with altered gut flora in babies 3-4 months old were strongest for frequent use of household disinfectants such as multi-surface cleaners, which showed lower levels of Haemophilus and Clostridium bacteria but higher levels of Lachnospiraceae.

The researchers also observed an increase in Lachnospiraceae bacteria with more frequent cleaning with disinfectants.

They, however, did not find the same association with detergents or eco-friendly cleaners.

“We found that infants living in households with disinfectants being used at least weekly were twice as likely to have higher levels of the gut microbes Lachnospiraceae at age 3-4 months,” said Anita Kozyrskyj, Professor at the University of Alberta in Canada.

Disinfectants
The researchers looked at data from the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort on microbes in infant fecal matter. Flcikr

“When they were 3 years old, their body mass index was higher than children not exposed to heavy home use of disinfectants as an infant,” Kozyrskyj said.

“Those infants growing up in households with heavy use of eco cleaners had much lower levels of the gut microbes Enterobacteriaceae,” she said.

Also Read: Asthma Ups The Chance of Obesity: Study

Kozyrskyj suggests that the use of eco-friendly products may be linked to healthier overall maternal lifestyles and eating habits, contributing in turn to the healthier gut microbiomes and weight of their infants. (IANS)