Sunday December 16, 2018

Consuming Mediterranean Diet Prevents Risk of Age-related Blindness

The entire pattern of eating a nutrient-rich diet, instead of individual food varieties such as fish, fruits and vegetables, helps significantly curb the risk of late AMD, the researchers noted

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Mediterranean Food, (representational Image) Wikimedia
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Consuming a Mediterranean diet rich in fruits, vegetables, grains, potatoes, olive oil, seeds, fish, low saturated fat, dairy products and red meat can help prevent potential blindness in later stages of life, a study has found.

Age-related macular degeneration (AMD) is a degenerative eye disease and a leading cause of vision loss among people age 50 and older.

It causes loss of central vision, which is crucial for simple everyday activities, such as the ability to see faces, drive, read, and write.

In analysing the connection between genes and lifestyle on the development of AMD, researchers from the European Union found that people who adhered to a Mediterranean diet cut their risk of late-stage AMD by 41 per cent.

The findings, published in the journal Ophthalmology, expands on previous studies and suggests that such a diet is beneficial for everyone, whether you already have the disease or are at risk of developing it.

Mediterranean Diet
Mediterranean Diet. Pixabay

“I believe this is a public health issue on the same scale as smoking. Chronic diseases such as AMD, dementia, obesity, and diabetes, all have roots in poor dietary habits. It’s time to take quitting a poor diet as seriously as quitting smoking,” said Emily Chew, a clinical spokesperson for the American Academy of Ophthalmology.

Previous research has linked Mediterranean diet to a longer lifespan and a reduced incidence of heart disease and cognitive decline.

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For the new study, the team analysed food-frequency questionnaires from nearly 5,000 people who participated in two investigations focused separately on disease risks in people aged 55 and older and the links between eye diseases and nutritional factors in people aged 73 and older.

The entire pattern of eating a nutrient-rich diet, instead of individual food varieties such as fish, fruits and vegetables, helps significantly curb the risk of late AMD, the researchers noted. (IANS)

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New Drug Offers Treatment For Diabetes-Related Blindness

The researchers now plan to conduct a full-scale clinical trial, Gamble said

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new policy will see the launch of 12 programmes relevant to private schools across the emirate
New drug offers hope for diabetes-related blindness.

In a major breakthrough, Australian scientists have developed a new drug that offers treatment for people suffering from diabetic retinopathy — the main cause of blindness from diabetes.

The debilitating disease occurs when tiny blood vessels in the retina, responsible for detecting light, leak fluid or haemorrhage.

While treatment options include laser surgery or eye injections of anti-vascular endothelial growth factor (VEGF), they are not always effective or can result in side effects, highlighting the need for alternative therapeutic approaches.

The team from the Centenary Institute in Sydney developed a novel drug CD5-2, which in mouse models was found to mend the damaged blood retinal barrier and reduce vascular leakage.

“We believe CD5-2 could potentially be used as a stand-alone therapy to treat those patients who fail to respond to the anti-VEGF treatment. It may also work in conjunction with existing anti-VEGF treatments to extend the effectiveness of the treatment,” said lead author Ka Ka Ting from the Institute.

“With limited treatment options currently available, it is critical we develop alternative strategies for the treatment of this outcome of diabetes,” Ting added.

Diabetes
Representational image. Pixabay

The key process involved in diabetic retinopathy pathology is the breakdown of the blood-retinal barrier (BRB), which is normally impermeable. Its integrity relies on how well capillary endothelial cells are bound together by tight junctions. If the junctions are loose or damaged, the blood vessels can leak.

In the study, reported in the journal Diabetologia, CD5-2 was found to have therapeutic potential for individuals with vascular-leak-associated retinal diseases based on its ease of delivery and its ability to reverse vascular dysfunction as well as inflammatory aspects in animal models of retinopathy.

Previous studies have shown that CD5-2 can have positive effects on the growth of blood vessels.

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“This drug has shown great promise for the treatment of several major health problems, in the eye and in the brain,” said Professor Jenny Gamble, head of Centenary’s Vascular Biology Programme.

The researchers now plan to conduct a full-scale clinical trial, Gamble said. (IANS)