Sunday October 21, 2018

Consuming Mediterranean Diet Prevents Risk of Age-related Blindness

The entire pattern of eating a nutrient-rich diet, instead of individual food varieties such as fish, fruits and vegetables, helps significantly curb the risk of late AMD, the researchers noted

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Mediterranean Food, (representational Image) Wikimedia
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Consuming a Mediterranean diet rich in fruits, vegetables, grains, potatoes, olive oil, seeds, fish, low saturated fat, dairy products and red meat can help prevent potential blindness in later stages of life, a study has found.

Age-related macular degeneration (AMD) is a degenerative eye disease and a leading cause of vision loss among people age 50 and older.

It causes loss of central vision, which is crucial for simple everyday activities, such as the ability to see faces, drive, read, and write.

In analysing the connection between genes and lifestyle on the development of AMD, researchers from the European Union found that people who adhered to a Mediterranean diet cut their risk of late-stage AMD by 41 per cent.

The findings, published in the journal Ophthalmology, expands on previous studies and suggests that such a diet is beneficial for everyone, whether you already have the disease or are at risk of developing it.

Mediterranean Diet
Mediterranean Diet. Pixabay

“I believe this is a public health issue on the same scale as smoking. Chronic diseases such as AMD, dementia, obesity, and diabetes, all have roots in poor dietary habits. It’s time to take quitting a poor diet as seriously as quitting smoking,” said Emily Chew, a clinical spokesperson for the American Academy of Ophthalmology.

Previous research has linked Mediterranean diet to a longer lifespan and a reduced incidence of heart disease and cognitive decline.

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For the new study, the team analysed food-frequency questionnaires from nearly 5,000 people who participated in two investigations focused separately on disease risks in people aged 55 and older and the links between eye diseases and nutritional factors in people aged 73 and older.

The entire pattern of eating a nutrient-rich diet, instead of individual food varieties such as fish, fruits and vegetables, helps significantly curb the risk of late AMD, the researchers noted. (IANS)

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Gene Therapy Wins Big at Portugal’s Champalimaud Foundation

The foundation, which focuses on neuroscience and oncology research at its Lisbon base, was set up at the bequest of Portugal's late industrialist Antonio Champalimaud.

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Gene Theory
ean Bennett, Albert Maguire, Robin Ali, James Bainbridge, Samuel Jacobson, T. Michael Redmond and Portugal's President Marcelo Rebelo de Sousa attend the 2018 Antonio Champalimaud Vision Awards ceremony at Champalimaud Foundation in Lisbon, Portugal, VOA

Seven scientists in the United States and Britain who have come up with a revolutionary gene therapy cure for a rare genetic form of childhood blindness won a 1 million euro ($1.15 million) prize Tuesday, Portugal’s Champalimaud Foundation said.

Established in 2006, the annual award for work related to vision is one of the world’s largest science prizes, more than the latest 9 million Swedish crown ($987,000) Nobel Prize in Physiology or Medicine.

“This is the first, and still only, example of successful gene therapy in humans that corrects an inherited genetic defect and is therefore a milestone in medical therapeutics,” said Alfred Sommer, Dean Emeritus of the Johns Hopkins Bloomberg School of Public Health and chairman of the award jury.

Gene
Colour sensitivity can also led to Retinal Diseases/Blindness. Pixabay

One of those honored, Michael Redmond of the National Eye Institute in Maryland, had traced the cause of the disease, Leber congenital amaurosis (LCA), to a mutated gene.

Three cooperating research teams later managed to replace the gene in the eye, restoring vision to treated children and adults with one form of LCA and “enabling the entire field of gene therapy for human disease,” the foundation said.

These teams are comprised of U.S. scientists Jean Bennett and Albert Maguire; Samuel Jacobson and William Hauswirth; and Britons Robin Ali and James Bainbridge.

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Their gene augmentation therapy involved the delivery of healthy genes using engineered harmless viruses, described by the foundation as “an elegant solution.”

The foundation, which focuses on neuroscience and oncology research at its Lisbon base, was set up at the bequest of Portugal’s late industrialist Antonio Champalimaud who died in 2004. The first vision prize was awarded in 2006. (VOA)