Thursday October 17, 2019

Researchers Claim, Men Aged 45 And Older Can Experience Decreased Fertility

Infants born to older fathers were found to be at higher risk of premature birth, late still birth, low birth weight, higher incidence of newborn seizures and birth defects such as congenital heart disease and cleft palate.

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Bachmann attributes most of these outcomes to a natural decline in testosterone that occurs with ageing, as well as sperm degradation and poorer semen quality. Pixabay

Men who delay starting a family have a ticking “biological clock” — just like women — that may affect the health of their partners and children, according to the researchers.

Men who delay fatherhood should consult their doctor and consider banking sperm before age 35, said the study which reviewed 40 years of research on the effect of parental age on fertility, pregnancy and the health of children.

“While it is widely accepted that physiological changes that occur in women after 35 can affect conception, pregnancy and the health of the child, most men do not realize their advanced age can have a similar impact,” said Gloria Bachmann, Director of the Women’s Health Institute at Rutgers University’s Robert Wood Johnson Medical School.

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“For example, just as people lose muscle strength, flexibility and endurance with age, in men, sperm also tends to lose ‘fitness’ over the life cycle,” she said.Pixabay

The study, published in the journal Maturitas, found that men aged 45 and older can experience decreased fertility and put their partners at risk for increased pregnancy complications such as gestational diabetes, preeclampsia and preterm birth.

Infants born to older fathers were found to be at higher risk of premature birth, late still birth, low birth weight, higher incidence of newborn seizures and birth defects such as congenital heart disease and cleft palate.

As they matured, these children were found to have an increased likelihood of childhood cancers, psychiatric and cognitive disorders, and autism.

Bachmann attributes most of these outcomes to a natural decline in testosterone that occurs with ageing, as well as sperm degradation and poorer semen quality.

“For example, just as people lose muscle strength, flexibility and endurance with age, in men, sperm also tends to lose ‘fitness’ over the life cycle,” she said.

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As they matured, these children were found to have an increased likelihood of childhood cancers, psychiatric and cognitive disorders, and autism. Pixabay

The study also found that older men struggled with fertility issues even if their partner was under 25.

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“While women tend to be more aware and educated than men about their reproductive health, most men do not consult with physicians unless they have a medical or fertility issue,” Bachmann said.

She recommended that physicians counsel older men as they do older women on the effect their age will have on conception, pregnancy and the health of their child. (IANS)

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Children Born to Women with Hyperemesis may be at Increased Risk of Autism

This could lead to dangerous dehydration and inadequate nutrition during pregnancy

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Mothers, Morning Sickness, Pregnancy
Affected women experience intense nausea and are unable to keep down food and fluids. Pixabay

Children whose mothers had hyperemesis gravidarum, a severe form of morning sickness, during pregnancy were 53 per cent more likely to be diagnosed with an autism spectrum disorder, a study said.

Hyperemesis gravidarum occurs in less than five per cent of pregnancies. Affected women experience intense nausea and are unable to keep down food and fluids.

This could lead to dangerous dehydration and inadequate nutrition during pregnancy.

“This study is important because it suggests that children born to women with hyperemesis may be at an increased risk of autism,” said the study’s lead author Darios Getahun, Kaiser Permanente Southern California Department of Research and Evaluation.

Mothers, Morning Sickness, Pregnancy
Hyperemesis gravidarum occurs in less than five per cent of pregnancies. Pixabay

“Awareness of this association may create the opportunity for earlier diagnosis and intervention in children at risk of autism,” Getahun said,

For the study published in the American Journal of Perinatology, researchers reviewed the electronic health records of nearly 500,000 pregnant women and their children born between 1991-2014 in Southern California.

They compared children whose mothers had a diagnosis of hyperemesis gravidarum during pregnancy to those whose mothers did not.

The researchers found that exposure to hyperemesis gravidarum was associated with increased risk of autism when the disease was diagnosed during the first and second trimesters of pregnancy, but not when it was diagnosed only in the third trimester.

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Exposure to the disease was associated with the risk of autism regardless of the severity of the mother’s hyperemesis gravidarum, the study said.

The results are consistent with the hypothesis that women experiencing hyperemesis gravidarum have a poor nutritional intake, which might, in turn lead to potential long-term neurodevelopment impairment in their children. (IANS)