Sunday December 8, 2019

Metabolic Surgery may Significantly Reduce Risk of Death from Heart Complications

The striking results that we saw after metabolic surgery may be related to the patients' substantial and sustained weight loss

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Metabolic Surgery, Death, Heart
The surgery also help patients with Type-2 diabetes and obesity in controlling the condition and in treatment of cardiovascular diseases compared with people undergoing usual medical care, according to the findings. Pixabay

In addition to reducing weight, bariatric or metabolic surgery may significantly reduce risk of death from heart complications, says a study.

The surgery also help patients with Type-2 diabetes and obesity in controlling the condition and in treatment of cardiovascular diseases compared with people undergoing usual medical care, according to the findings.

“The striking results that we saw after metabolic surgery may be related to the patients’ substantial and sustained weight loss,” said the study’s lead author Ali Aminian, a bariatric surgeon at Cleveland Clinic, Ohio, the USA.

“There is a growing body of evidence to suggest beneficial metabolic and hormonal changes after the surgical procedures that are independent of weight loss,” Aminian said.

Metabolic Surgery, Death, Heart
In addition to reducing weight, bariatric or metabolic surgery may significantly reduce risk of death from heart complications, says a study. Pixabay

The study compared nearly 2,300 patients who underwent metabolic surgery with 11,500 patients with similar characteristics but under usual medical care.

Patients underwent one of the four types of weight-loss surgery — gastric bypass, sleeve gastrectomy, adjustable gastric banding, or duodenal switch.

The primary endpoint of the study was occurrence of death due to one of the five major complications associated with obesity and diabetes — coronary artery events, cerebrovascular issues, heart failure, atrial fibrillation and kidney disease.

Over an eight-year period, it was found that patients of metabolic surgery were 40 per cent less likely to experience one of these events than those receiving usual medical care.

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Patients in the surgical group were 41 per cent less likely to die from any of these causes and had 15 per cent greater weight loss and lower blood sugar levels. They used less medication, including insulin, and less heart medications, like blood pressure and cholesterol therapies, compared with the non-surgery group.

The results were presented at the European Society of Cardiology Congress in Paris, France, and also published in the Journal of the American Medical Association (JAMA). (IANS)

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Children of Diabetic Mothers May Develop Heart Risks: Study

Kids born of diabetic mothers at heart risk

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Diabetes- heart
Children of mothers with diabetes have increased rates of early onset heart diseases. Pixabay

Children of mothers with diabetes have increased rates of early onset cardiovascular disease or CVD (conditions affecting the heart or blood vessels) from childhood up to the age of 40, the researchers have warned.

The increased rates were more pronounced among children of mothers with a history of CVD or diabetic complications, said the study published in the journal The BMJ.

“our study provides evidence that children of mothers with diabetes, especially those with a history of CVD or with diabetic complications, had increased rates of early onset CVD throughout the early decades of life,” said study researchers from Aarhus University in Denmark.

If this association is shown to be causal, preventing, screening, and treating diabetes in women of childbearing age could be important not only for improving the health of the women but also for reducing long term risks of CVD in their offspring, the researchers added

The number of women diagnosed with diabetes before or during pregnancy has increased globally, and children of these women are more likely to have risk factors for future CVD, such as high blood pressure and high blood sugar levels.

It is unclear, however, whether or to what extent exposure to diabetes in the womb increases the risk of developing CVD in offspring over a lifetime.

Heart disease
Children with diabetic mothers may develop CVD which may increase heart complications. Pixabay

So an international team of researchers set out to evaluate associations between diabetes diagnosed before or during pregnancy and early onset CVD in children during their first four decades of life.

They base their findings on national registry data for over 2.4 million children born without congenital heart disease in Denmark from 1977 to 2016.

Diabetes was categorised as pregestational (before pregnancy) or gestational (during pregnancy) and women with diabetic complications were identified.

Other potentially influential factors, such as mother’s age, education, lifestyle and medical history were also taken into account.

During up to 40 years of follow-up, children of mothers with diabetes had a 29 per cent increased overall rate of early onset CVD compared with children of mothers who did not have diabetes (cumulative risks: 17.8 per cent vs 13.1 per cent ).

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The researchers also found higher rates for specific types of CVD children of mothers with diabetes, particularly heart failure (45 per cent), hypertensive disease (78 per cent), deep vein thrombosis (82 per cent), and pulmonary embolism (91 per cent).

Increased rates were seen in each age group in childhood (before 20 years of age) and early adulthood (from 20 to 40 years of age), regardless of the type of diabetes they were exposed to (pregestational or gestational) and rates were similar for both type 1 and type 2 diabetes, the study said. (IANS)