Wednesday May 22, 2019

Researchers Develop, New Adhesive Patch That Can Minimize Heart Attack Damage

For the research, published in Nature Biomedical Engineering, the team tested the patch with rats and showed that the patch could be effective in reducing post-heart attack damage. 

0
//
Heart
The researchers said the patch, which costs "less than a penny", has been optimised using a computer model of the heart to perfectly match the material's mechanical properties. Pixabay

Researchers have developed a new adhesive patch that could reduce the stretching of cardiac muscle following a heart attack.

Developed by a team of researchers from Brown University, US; Fudan University, China and Soochow University, China, the patch is made from a water-based hydrogel material and can be placed directly on the heart to prevent left ventricular remodelling — a stretching of the heart muscle.

A heart attack puts the cardiac muscle at a risk of stretching out that can reduce the functioning of the heart’s main pumping chamber.

ecg
The researchers say the initial results are promising for eventual use in human clinical trials. Pixabay

“Part of the reason that it’s hard for the heart to recover after a heart attack is that it has to keep pumping,” said co-author Huajian Gao, a professor at Brown University.

“The idea here is to provide mechanical support for damaged tissue, which hopefully gives it a chance to heal,” he added.

The researchers said the patch, which costs “less than a penny”, has been optimised using a computer model of the heart to perfectly match the material’s mechanical properties.

“If the material is too hard or stiff, then you could confine the movement of the heart so that it can’t expand to the volume it needs to,” Gao said.

“But if the material is too soft, then it won’t provide enough support. So we needed some mechanical principles to guide us,” he pointed out.

For the research, published in Nature Biomedical Engineering, the team tested the patch with rats and showed that the patch could be effective in reducing post-heart attack damage.

heart
A heart attack puts the cardiac muscle at a risk of stretching out that can reduce the functioning of the heart’s main pumping chamber. Pixabay

“The patch provided nearly optimal mechanical supports after myocardial infarction (i.e. massive death of cardiomyocytes),” said co-author Ning Sun, a cardiology researcher at Fudan University.

“[It] maintained a better cardiac output and thus greatly reduced the overload of those remaining cardiomyocytes and adverse cardiac remodelling.”

Also Read: China’s Political System Helps It To Take A Lead in Artificial Intelligence

The researchers say the initial results are promising for eventual use in human clinical trials.

“It remains to be seen if it will work in humans, but it’s very promising,” Gao said. (IANS)

Next Story

India And Germany Collaborate For Research in Biological Applications

"The topics of this research training group are highly relevant for developing the biotechnology industry in both countries," Michael J. Winckler, Programme Coordinator at Heidelberg, said in a statement. 

0
Research
The six institutes -- Indian Institutes of Technology at Guwahati, Kanpur and Madras, University of Allahabad, University of Delhi and Jawaharlal Nehru University -- will partner with Germany's Heidelberg University, and Department of Biotechnology (DBT) under the Ministry of Science and Technology. Pixabay

In a bid to promote the use of big data methods in biological applications, six Indian institutes of higher education on Wednesday established the first joint Indo-German research training group (RTG).

The six institutes — Indian Institutes of Technology at Guwahati, Kanpur and Madras, University of Allahabad, University of Delhi and Jawaharlal Nehru University — will partner with Germany’s Heidelberg University, and Department of Biotechnology (DBT) under the Ministry of Science and Technology.

web
The first funding of the programme will be between 2019 and 2025 with an investment of three million euros each from Heidelberg and DBT, the statement said. Pixabay

The programme aims at setting up as many as 50 Ph.D. projects, on “Bio Big Data Science”, which will be supervised by research teams consisting of leading Indian and German scientists.

Also Read: YouTube Shuts Down The Comment Section on Its Livestream Expressing Of Anti-Semitic Views

“The topics of this research training group are highly relevant for developing the biotechnology industry in both countries,” Michael J. Winckler, Programme Coordinator at Heidelberg, said in a statement.

The first funding of the programme will be between 2019 and 2025 with an investment of three million euros each from Heidelberg and DBT, the statement said. (IANS)