Wednesday June 26, 2019

Learn How Muscles Help Burn Fat During Exercise

Burning fat is likely to impact multiple aspects of metabolic health related to diabetes, heart disease and other conditions

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How exercise can help breast cancer survivors. Pixabay

Ever thought what helps burn fat across your body while exercising? According to a study, it is a molecule in our muscles that is produced during exercise and contributes to the beneficial effects of exercise on metabolism.

“Our finding bolsters the underlying notion that signals generated in exercising muscle are released into the circulation and influence other tissues such as fat cells and liver,” said senior author Robert Gerszten at Massachusetts General Hospital, the primary teaching hospital of Harvard Medical School.

The researchers knew that a protein called PGC-1? regulates metabolic genes in muscle and contributes to the response of muscle to exercise.

But how this protein conveys signals to other tissues was unclear so far.

Gerszten and his colleagues forced the expression of PGC-1? in muscle cells and then looked for metabolites that were secreted from the cells.

Exercise
BAIBA also decreased weight gain and helped balance blood sugar levels in mice, said the study published in the journal Cell Metabolism. Pixabay

They identified ?-aminoisobutyric acid (BAIBA) as one such metabolite and found that it increased fat cells’ expression of genes that are involved with burning calories.

BAIBA also decreased weight gain and helped balance blood sugar levels in mice, said the study published in the journal Cell Metabolism.

Further research revealed that BAIBA levels rise during exercise and are inversely associated with metabolic risk factors.

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“The findings suggest that BAIBA may contribute to exercise-induced protection from metabolic diseases. Manipulating BAIBA – or enzymes that generate BAIBA – may have therapeutic potential,” said Gerszten.

Burning fat is likely to impact multiple aspects of metabolic health related to diabetes, heart disease and other conditions, the study concluded.  (IANS)

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Exercising at Home as Fruitful as Gyming

For the study, 32 obese people completed a 12-week exercise programme

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Exercise best defence against deep abdominal belly fat. Pixabay

If you are not finding time to hit the gym, do not worry. Researchers have found that working out at home not only saves your time, cost and access but also increases adherence.

The study, published in The Journal of Physiology, investigated a home-based high-intensity interval training (Home-HIT) programme and studied its benefits for clinically obese individuals with an elevated risk of heart disease.

The research team were interested in whether Home-HIT is a time-efficient strategy that helps to reduce other common exercise barriers such as difficulty with access to exercise facilities due to travel time and cost.

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Researchers have found that working out at home not only saves your time, cost and access but also increases adherence. Pixabay

“An exercise regimen such as Home-HIT that reduces barriers to exercise such as time, cost, and access, and increases adherence in previously inactive individuals gives people a more attainable exercise goal and thus could help improve the health of countless individuals,” said study author Sam Scott from Liverpool John Moores University.

For the study, 32 obese people completed a 12-week exercise programme. A range of health markers were measured in these participants, including body composition, cardiovascular disease risk and the ability to regulate glucose.

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A range of health markers were measured in these participants, including body composition, cardiovascular disease risk and the ability to regulate glucose. Wikimedia Commons

They were categorised in three groups — those who did supervised, lab-based cycling HIT programme; those who did UK government-recommended 150 minutes of moderate intensity exercise; and those who did home-based HIT programme of simple body weight exercises suitable for people with low fitness and low mobility and performed without equipment.

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The researchers found that home-based HIT was as effective as both the government-recommended 150-minute exercise and the supervised, lab-based HIT programme for improving fitness in obese individuals. (IANS)