Wednesday October 23, 2019

Researchers Develop Nano Technology That Offers Hope For Better Cancer Testing

The study has been published in the journal Advanced Materials

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Breast Cancer
Nano technology offers hope for better cancer testing. Pixabay

Researchers have designed a new nano tool which could become a new way of mining blood samples for information about cancer, according to a study released on Wednesday by the University of Manchester.

Minimally invasive blood tests have the potential to detect and monitor life-threatening diseases such as cancer. But the markers released into the bloodstream as a response to a disease are often difficult to detect because they are too small and too few in number, Xinhua news agency reported.

The study, led by researchers from the University of Manchester showed that small molecules — specifically proteins — stick to the nanoparticles while in the blood circulation of cancer patients. Collecting the nanoparticles from the blood can then allow the analysis of the sticky molecules, some of which are released from the growing cancer.

Cancer
Cancer Ribbon. Pixabay

“We want to amplify cancer signals in the blood that would otherwise be buried among all this other ‘molecular noise’,” said study author Prof Kostas Kostarelos from Manchester.

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“Our team hopes to discover panels of biomolecules that can point to early warning signs of cancer which will provide the basis for the development of new diagnostic tests”, said Prof Kostarelos.

The study has been published in the journal Advanced Materials. (IANS)

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Study Says, Men With Breast Cancer Face High Mortality Rates

The study used 11 years of registry data from January 1, 2004, to December 31, 2014, which included 1.8 million female and 16,025 male patients

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Men
Other factors that might influence mortality rates among Men could be lifestyle factors, such as smoking, alcohol consumption, physical inactivity and obesity. Pixabay

Men with breast cancer are more likely to have lower overall survival rates than their female counterparts, a study said.

“The persistent disparity, derived from an analysis of data from the National Cancer Database, suggests a possible distinct cancer biology, less effective treatment or compliance issues, and perhaps unhealthy lifestyles among men may be responsible for the lower overall survival rates,” said the study’s senior author Xiao-Ou Shu from the Vanderbilt University in the US.

The five-year mortality rate for men was 19 per cent higher than women, according to the research published in the journal JAMA Oncology.

The study used 11 years of registry data from January 1, 2004, to December 31, 2014, which included 1.8 million female and 16,025 male patients.

About 85 per cent of male breast cancer is Estrogen receptor (ER)-positive, a proportion that is higher than female breast cancer patients (75 per cent).

“That is a cancer type where patients usually fare better because we have a hormonal treatment.

“We have a lot of treatment options for that type of breast cancer. In theory, men should have better outcomes and have lower mortality as women do if the treatment is equally effective,” Shu said.

According to the researchers, previous studies have shown that men might not be as compliant with hormonal treatments as women.

Men
The five-year mortality rate for Men was 19 per cent higher than women, according to the research published in the journal JAMA Oncology. Pixabay

Other factors that might influence mortality rates among men could be lifestyle factors, such as smoking, alcohol consumption, physical inactivity and obesity.

Clinical characteristics and under treatments were associated with 63 per cent of the sex-related mortality disparity.

ALSO READ: Pancreatic, Colorectal Cancer up 10% in 30 Years, Says Study

“The bottom line is that we need more studies specifically focused on male breast cancer,” Shu added. (IANS)