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Here Comes The New Acne Vaccine

Future studies will address these factors and focus on engineering a non-toxic chemical or targeted vaccine formulation for its human application, the researchers said

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Acne
New vaccine to offer treatment for acne. Pixabay

Do you often suffer from acne? Take heart, a potential vaccine that targets the bacterial toxins may soon be on the anvil, say researchers.

Instead of invading pathogens, the new vaccine would be the first to target bacteria already in human skin.

The researchers demonstrated that antibodies to a toxin secreted from bacteria in acne vulgaris can reduce inflammation in human acne lesions.

“Once validated by a large-scale clinical trial, the potential impact of our findings is huge for the hundreds of millions of individuals suffering from acne vulgaris,” explained lead investigator Chun-Ming Huang, from the University of California-San Diego, US.

An acne vaccination could circumvent potential adverse effects of topical or systemic retinoids and antibiotics, the current treatment options.

acne
Instead of invading pathogens, the new vaccine would be the first to target bacteria already in human skin. Pixabay

They found that Christie-Atkins-Munch-Peterson (CAMP) factor — a toxin secreted from the Propionibacterium acnes (P. acnes) bacteria, can induce inflammatory responses.

In the study, published in the Journal of Investigative Dermatology, the team explored in mice and ex vivo in human skin cells whether they could inhibit inflammation by employing antibodies to neutralise this virulence factor.

Their findings show that the application of monoclonal antibodies to CAMP 2 factor did indeed decrease the inflammatory response.

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“While addressing an unmet medical need and providing an appealing approach, acne immunotherapies that target P. acnes-derived factors have to be cautiously designed to avoid unwanted disturbance of the microbiome that guarantees skin homeostasis,” said Emmanuel Contassot, from the University of Zurich in Switzerland.

Future studies will address these factors and focus on engineering a non-toxic chemical or targeted vaccine formulation for its human application, the researchers said. (IANS)

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Instagram, Facebook to Remove Vaccine Misinformation Content: Report

Since both the social networking platforms are heavily used by advertisers, ads found to include fake news on vaccinations would be rejected outright

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Instagram
Instagram app logo is displayed on a mobile screen in Los Angeles. VOA

As part of their effort to reduce the spread of “vaccine hoaxes” on its platform, Facebook and its photo-messaging app Instagram will no longer allow advertisements that include misinformation about vaccines.

The company has decided to take action against accounts which are promoting vaccine hoaxes that have been publicly identified by the World Health Organisation and Centres for Disease Control and Prevention, US.

“We want to give people more accurate information from expert organisations about vaccines at the top of results for related searches, on Pages discussing the topic, and on invitations to join groups about the topic,” Monika Bickert, Vice President, Global Policy Management, Facebook wrote in a blog-post on Thursday.

As part of the initiative, the Facebook Pages that spread misinformation about vaccinations in News Feed and Search would not be included in recommendations or predictions.

facebook
Facebook: The platform allows for different types of content, which makes it ideal for diverse, interactive and entertaining content.

On Instagram, recommended content on vaccinations that could contain wrong information would not show up in the Explore tab and hashtag pages.

Since both the social networking platforms are heavily used by advertisers, ads found to include fake news on vaccinations would be rejected outright.

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“For ad accounts that continue to violate our policies, we may take further action, such as disabling the ad account,” Bickert said.

“We are exploring ways to share educational information about vaccines when people come across misinformation on this topic,” she added. (IANS)