Friday November 22, 2019

New biomarker for breast and prostate cancers found

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New York : Researchers have identified a novel genetic biomarker responsible for the progression of many breast and prostate cancers.

The finding could bolster efforts to better identify patients who respond to certain types of chemotherapy drugs that attack the most aggressive forms of cancer.

“Understanding and identifying biomarkers is a vital step toward cancer research and care,” said lead study author Michael Freeman from Cedars-Sinai Medical Centre in Los Angeles, California, US.

“New profiling strategies exemplified by this study will ultimately improve our ability to treat cancer patients,” Freeman noted.

The newly identified genetic biomarker – diaphanous- related formin-3 or DIAPH3 – participates in a protein interaction that makes cells rigid.

The study found that when this biomarker is lost or lowered, cells become “deformable,” squeezing through tissue spaces, causing disease growth or progression.

The study was published in the journal Scientific Reports.

(IANS)

 

 

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Beware! Velvety ‘Triple Palms’ Can be Sign of Lung Cancer

"All patients with tripe palms should be evaluated with a full diagnostic work-up for an associated malignancy, particularly lung or gastric carcinoma," wrote the researchers

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Velvety palms constitute a rare medical condition known as 'tripe palms', due to their resemblance to the rippled appearance of the stomach lining of cows, pigs or sheep. Pixabay

In a rare medical condition, a 73-year-old Brazilian woman was diagnosed with lung cancer after she showed up at a dermatologist’s clinic with velvety ‘triple palms’.

An elderly smoker who acknowledged that she’d gone through a pack of cigarettes every day for 30 years, the woman was suffering from painful lesions on her hands.

According to Science Alert that cited a case published in a paper in The New England Journal of Medicine, she also had cough for about a year, and had lost 5 kg in the last four months alone.

“Physical examination revealed sharp demarcation of the folds in the lines of her hands in addition to a velvety appearance of palmar surfaces and ridging of the skin,” her doctors wrote in the case report.

Velvety palms constitute a rare medical condition known as ‘tripe palms’, due to their resemblance to the rippled appearance of the stomach lining of cows, pigs or sheep.

Cancer
Cancer Ribbon. Pixabay

Sometimes called acanthosis palmaris, such tripe palms fall under skin disorder.

In the case of this 73-year-old patient, a CT scan revealed irregularities in her lungs.

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A subsequent biopsy confirmed the diagnosis of adenocarcinoma, and she underwent chemotherapy and radiation therapy, said the report.

“All patients with tripe palms should be evaluated with a full diagnostic work-up for an associated malignancy, particularly lung or gastric carcinoma,” wrote the researchers. (IANS)