Friday June 21, 2019

New Device Equally Harmful as E-cigarettes

"If the current trend continues, tobacco use will cause more than eight million deaths annually by 2030 around the world," noted Sharma

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E-cigarettes, Smokers
Talia Eisenberg, co-founder of the Henley Vaporium, uses her vaping device in New York, Feb. 20, 2014. VOA

While we know about the harmful effects of traditional cigarettes and vaping, new heated tobacco devices are no less toxic to the human lung cells than ordinary cigarette smoke, said researchers, including one of Indian-origin.

The study has compared new heated tobacco devices, which heat solid tobacco instead of an e-liquid, with vaping and traditional cigarettes showing that all the three are toxic to the cells.

In addition, these newer electronic nicotine delivery devices can destroy lung tissue leading to fatal diseases such as chronic obstructive pulmonary disease, lung cancer and pneumonia, and can increase the risk of developing asthma.

“Smoking is the leading cause of preventable death, and with the introduction of e-cigarettes in the last decade, the trend of nicotine uptake is not going to slow down in the near future,” said Pawan Sharma, a researcher at the University of Technology Sydney.

“The latest addition in this emerging trend is the planned and vigorous introduction of heated tobacco devices. They are commonly called next generation or heat-not-burn products. We know very little about the health effects of these new devices, so we designed this research to compare them with cigarette smoking and vaping,” added Sharma.

For the study, researchers tested the effects of all three nicotine sources on two types of cells taken from the human airways: epithelial cells and smooth muscle cells.

E-cigarettes, Smokers
A woman smokes an electronic cigarette in London, Aug. 19, 2015. VOA

In healthy lungs, epithelial cells act as the first line of defence to any foreign particles entering the airway while smooth muscle cells maintain the structure of the airway. However, smoking can lead to difficulty in breathing primarily by hampering the normal functions of these cells.

The team exposed the cells to different concentrations of cigarette smoke, e-cigarette vapour and vapour from a heated tobacco device, and measured whether this was damaging to cells and whether it affected the cells’ normal functions.

The findings, published in ERJ Open Research, showed that cigarette smoke and heated tobacco vapour were highly toxic to the cells both at lower and higher concentrations while e-cigarette vapour demonstrated toxicity mainly at higher concentrations.

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Importantly, the review of the European Respiratory Society’s Tobacco Control Committee’s own data on these devices has shown that, in rats, there is evidence of lung inflammation, and there is no evidence of improvement in lung inflammation and function in smokers who switch to heated tobacco, said Professor Charlotta Pisinger from the varsity.

“If the current trend continues, tobacco use will cause more than eight million deaths annually by 2030 around the world,” noted Sharma. (IANS)

Next Story

Smoking May Increase Risk of Developing Hypertension, Warn Researchers

The results were published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

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FILE - New findings show that smoking causes devastating genetic damage, or mutations, in the cells of various organs in the body. VOA

Smoking may increase the risk of developing hypertension by impairing the body’s blood pressure autocorrect system, warn researchers.

“The human body has a buffering system that continuously monitors and maintains a healthy blood pressure. If blood pressure drops, a response called muscle sympathetic nerve activity (MSNA) is triggered to bring blood pressure back up to normal levels,” said Lawrence Sinoway from Penn State University in the US.

An additional system — called the baroreflex — helps correct if blood pressure gets too high, he added.

According to Sinoway, the study found that after a burst of MSNA, the rise in blood pressure in a chronic smoker was about twice as great as in a non-smoker, pushing blood pressure to unhealthy levels. The researchers suspect that impairment of baroreflex may be the culprit.

“When the sympathetic nervous system fires, like with MSNA, your blood pressure rises and then a series of things happen to buffer that increase, to try to attenuate it,” Sinoway said.

“We think that in smokers, that buffering — the baroreflex — is impaired.”

Other than chronic diseases, lifestyle habits like smoking causes cancer too. Pixabay
Other than chronic diseases, lifestyle habits like smoking causes cancer too. Pixabay

The results suggest that this impairment may be connected to hypertension, said Jian Cui, Associate Professor at Penn State College of Medicine.

“The greater rise in blood pressure in response to MSNA may contribute to a higher resting blood pressure level in smokers without hypertension,” Cui said.

“It’s possible that this higher response to MSNA could also contribute to the eventual development of hypertension,” Cui added.

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The researchers said that while previous research has found a link between chronic smokers and higher levels of MSNA bursts, less was known about what happened to blood pressure after these bursts.

For the study, the researchers examined 60 participants — 18 smokers and 42 non-smokers. None of the participants had hypertension.

The results were published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. (IANS)