Friday May 24, 2019

New Finding! Blood Test That Could Detect Risk Of Pre-Term Delivery

"Our goal is to develop prognostic markers for patients to help make predictions and offer highly personalised care to woman from early stages of pregnancy,"

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Mothers with history of pre-term deliveries face higher risks. But predicting spontaneous pre-term birth is challenging, particularly in the case of first-time mothers, the team said. Pixabay

Researchers are working on a blood test that could be able to detect risk of spontaneous pre-term delivery.
According to a study, published in the American Journal of Obstetrics & Gynaecology, five micro particle proteins found in first-trimester blood samples may give clues about the risk of spontaneous pre-term birth.

“Our goal is to develop prognostic markers for patients to help make predictions and offer highly personalised care to woman from early stages of pregnancy,” said co-author Thomas McElrath from the Brigham and Women’s Hospital in the US.

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Mothers with history of pre-term deliveries face higher risks. But predicting spontaneous pre-term birth is challenging, particularly in the case of first-time mothers, the team said. Pixabay

According to researchers, nearly 10 per cent births are taking place before 37-week gestation against the normal 40 weeks. Pre-term birth can result in several conditions, including pre-term labour, early rupture of the placental membrane or preeclampsia.

Mothers with history of pre-term deliveries face higher risks. But predicting spontaneous pre-term birth is challenging, particularly in the case of first-time mothers, the team said.

For the study, researchers studied blood samples, collected toward the end of the first trimester of pregnancy, from three established biobanks.

pregnancy
Mothers with history of pre-term deliveries face higher risks. But predicting spontaneous pre-term birth is challenging, particularly in the case of first-time mothers, the team said. Pixabay

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The team compared samples from 87 women who delivered at or before 35 weeks with samples from 174 women who delivered at term and were of the same age and at the same week of pregnancy at the time giving blood.

They analysed multiple circulating micro particles associated proteins and found that a subset of these proteins could help predict risks, both for the first-time mothers as well as those who had previously given birth. (IANS)

Next Story

Researchers Claim, Men Aged 45 And Older Can Experience Decreased Fertility

Infants born to older fathers were found to be at higher risk of premature birth, late still birth, low birth weight, higher incidence of newborn seizures and birth defects such as congenital heart disease and cleft palate.

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Bachmann attributes most of these outcomes to a natural decline in testosterone that occurs with ageing, as well as sperm degradation and poorer semen quality. Pixabay

Men who delay starting a family have a ticking “biological clock” — just like women — that may affect the health of their partners and children, according to the researchers.

Men who delay fatherhood should consult their doctor and consider banking sperm before age 35, said the study which reviewed 40 years of research on the effect of parental age on fertility, pregnancy and the health of children.

“While it is widely accepted that physiological changes that occur in women after 35 can affect conception, pregnancy and the health of the child, most men do not realize their advanced age can have a similar impact,” said Gloria Bachmann, Director of the Women’s Health Institute at Rutgers University’s Robert Wood Johnson Medical School.

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“For example, just as people lose muscle strength, flexibility and endurance with age, in men, sperm also tends to lose ‘fitness’ over the life cycle,” she said.Pixabay

The study, published in the journal Maturitas, found that men aged 45 and older can experience decreased fertility and put their partners at risk for increased pregnancy complications such as gestational diabetes, preeclampsia and preterm birth.

Infants born to older fathers were found to be at higher risk of premature birth, late still birth, low birth weight, higher incidence of newborn seizures and birth defects such as congenital heart disease and cleft palate.

As they matured, these children were found to have an increased likelihood of childhood cancers, psychiatric and cognitive disorders, and autism.

Bachmann attributes most of these outcomes to a natural decline in testosterone that occurs with ageing, as well as sperm degradation and poorer semen quality.

“For example, just as people lose muscle strength, flexibility and endurance with age, in men, sperm also tends to lose ‘fitness’ over the life cycle,” she said.

baby
As they matured, these children were found to have an increased likelihood of childhood cancers, psychiatric and cognitive disorders, and autism. Pixabay

The study also found that older men struggled with fertility issues even if their partner was under 25.

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“While women tend to be more aware and educated than men about their reproductive health, most men do not consult with physicians unless they have a medical or fertility issue,” Bachmann said.

She recommended that physicians counsel older men as they do older women on the effect their age will have on conception, pregnancy and the health of their child. (IANS)