Saturday October 19, 2019

New Finding! Blood Test That Could Detect Risk Of Pre-Term Delivery

"Our goal is to develop prognostic markers for patients to help make predictions and offer highly personalised care to woman from early stages of pregnancy,"

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pregnancy
Mothers with history of pre-term deliveries face higher risks. But predicting spontaneous pre-term birth is challenging, particularly in the case of first-time mothers, the team said. Pixabay

Researchers are working on a blood test that could be able to detect risk of spontaneous pre-term delivery.
According to a study, published in the American Journal of Obstetrics & Gynaecology, five micro particle proteins found in first-trimester blood samples may give clues about the risk of spontaneous pre-term birth.

“Our goal is to develop prognostic markers for patients to help make predictions and offer highly personalised care to woman from early stages of pregnancy,” said co-author Thomas McElrath from the Brigham and Women’s Hospital in the US.

blood
Mothers with history of pre-term deliveries face higher risks. But predicting spontaneous pre-term birth is challenging, particularly in the case of first-time mothers, the team said. Pixabay

According to researchers, nearly 10 per cent births are taking place before 37-week gestation against the normal 40 weeks. Pre-term birth can result in several conditions, including pre-term labour, early rupture of the placental membrane or preeclampsia.

Mothers with history of pre-term deliveries face higher risks. But predicting spontaneous pre-term birth is challenging, particularly in the case of first-time mothers, the team said.

For the study, researchers studied blood samples, collected toward the end of the first trimester of pregnancy, from three established biobanks.

pregnancy
Mothers with history of pre-term deliveries face higher risks. But predicting spontaneous pre-term birth is challenging, particularly in the case of first-time mothers, the team said. Pixabay

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The team compared samples from 87 women who delivered at or before 35 weeks with samples from 174 women who delivered at term and were of the same age and at the same week of pregnancy at the time giving blood.

They analysed multiple circulating micro particles associated proteins and found that a subset of these proteins could help predict risks, both for the first-time mothers as well as those who had previously given birth. (IANS)

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Children Born to Women with Hyperemesis may be at Increased Risk of Autism

This could lead to dangerous dehydration and inadequate nutrition during pregnancy

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Mothers, Morning Sickness, Pregnancy
Affected women experience intense nausea and are unable to keep down food and fluids. Pixabay

Children whose mothers had hyperemesis gravidarum, a severe form of morning sickness, during pregnancy were 53 per cent more likely to be diagnosed with an autism spectrum disorder, a study said.

Hyperemesis gravidarum occurs in less than five per cent of pregnancies. Affected women experience intense nausea and are unable to keep down food and fluids.

This could lead to dangerous dehydration and inadequate nutrition during pregnancy.

“This study is important because it suggests that children born to women with hyperemesis may be at an increased risk of autism,” said the study’s lead author Darios Getahun, Kaiser Permanente Southern California Department of Research and Evaluation.

Mothers, Morning Sickness, Pregnancy
Hyperemesis gravidarum occurs in less than five per cent of pregnancies. Pixabay

“Awareness of this association may create the opportunity for earlier diagnosis and intervention in children at risk of autism,” Getahun said,

For the study published in the American Journal of Perinatology, researchers reviewed the electronic health records of nearly 500,000 pregnant women and their children born between 1991-2014 in Southern California.

They compared children whose mothers had a diagnosis of hyperemesis gravidarum during pregnancy to those whose mothers did not.

The researchers found that exposure to hyperemesis gravidarum was associated with increased risk of autism when the disease was diagnosed during the first and second trimesters of pregnancy, but not when it was diagnosed only in the third trimester.

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Exposure to the disease was associated with the risk of autism regardless of the severity of the mother’s hyperemesis gravidarum, the study said.

The results are consistent with the hypothesis that women experiencing hyperemesis gravidarum have a poor nutritional intake, which might, in turn lead to potential long-term neurodevelopment impairment in their children. (IANS)