Sunday, September 20, 2020
Home Life Style Health & Fitness This New 'Ensilication' Method Allows Childhood Vaccines To be Kept Safe In...

This New ‘Ensilication’ Method Allows Childhood Vaccines To be Kept Safe In All Temperatures

The technique for tailor-fitting a vaccine with a silica coat - known as ensilication, keeps vaccines safe in all temperatures

Vaccines are difficult to transport to remote or dangerous places, as they spoil when not refrigerated but now researchers have developed a way to prevent warmed-up vaccines from degrading. By encasing protein molecules in a silica shell, the structure remains intact even when heated to 100 degrees Celsius, or stored at room temperature for up to three years. The technique for tailor-fitting a vaccine with a silica coat – known as ensilication- was developed by Bath University researchers in collaboration with the University of Newcastle in the UK.

This pioneering technology was seen to work in the lab two years ago, and now it has demonstrated its effectiveness in the real world too. “The aim is to eradicate vaccine-preventable diseases in low-income countries by using thermally stable vaccines and cutting out dependence on cold chain,” said study researcher Asel Sartbaeva from the University of Bath. Currently, up to 50 per cent of vaccine doses are discarded before use due to exposure to suboptimal temperatures.

vaccines
The technique for tailor-fitting a vaccine with a silica coat – known as ensilication- was developed by Bath University researchers in collaboration with the University of Newcastle in the UK. Pixabay

According to the World Health Organisation (WHO), 19.4 million infants did not receive routine life-saving vaccinations in 2018. In their latest study, published in the journal Scientific Reports, the research team sent both ensilicated and regular samples of the tetanus vaccine from Bath to Newcastle by ordinary post (a journey time of over 300 miles, which by post takes a day or two).

This project has focused on tetanus, which is part of the DTP (diphtheria, tetanus and pertussis) vaccine given to young children in three doses. When doses of the ensilicated vaccine were subsequently injected into mice, an immune response was triggered, showing the vaccine to be active. No immune response was detected in mice injected with unprotected doses of the vaccine, indicating the medicine had been damaged in transit.

Follow Newsgram on Quora for interesting answers

“This is really exciting data because it shows us that ensilication preserves not just the structure of the vaccine proteins but also the function – the immunogenicity,” Sartbaeva said. “Eventually, we want to create a silica cage for the whole DTP trivalent vaccine, so that every child in the world can be given DTP without having to rely on cold chain distribution,” the authors wrote.

Also Read: Devotees Rushed To Religious Places as Nationwide Lockdown Lifted

Silica is an inorganic, non-toxic material, and researchers estimate that ensilicated  vaccines could be used for humans within five to 15 years. They hope the technology to silica-wrap proteins will eventually be adopted to store and transport all childhood vaccines, as well as other protein-based products, such as antibodies and enzymes. (IANS)

STAY CONNECTED

19,152FansLike
362FollowersFollow
1,772FollowersFollow

Most Popular

Homemade Masks Effective At Blocking Droplets By Speaking, Coughing And Sneezing

Masks made with common household fabrics help prevent the spread of viruses like Covid-19 as researchers have found that they are considerably effective at...

Get Flu Shot to Avoid Having Covid and Flu Simultaneously

Health officials are warning the public to get a flu shot this year to avoid having to deal with COVID-19 and the flu simultaneously. Both...

India Couture Week Was Digital, Virtual And Democratic

It wasn't the familiar setting of the ballroom at the Taj Palace Hotel in the Capital, neither was it the familiar parade of 'shaadi'...

India’s Top Film Industry is Telugu Film Industry: Kangana Ranaut

Actress Kangana Ranaut says she wants film industries of different states to have a collective identity, and claims she wants to save the industry...

Planning a Road trip From Delhi? Here are 5 Must-Visit Destinations

By Siddhi Jain As several countries announced nationwide lockdowns in an effort to flatten the curve and break the chain, the coronavirus jolted the entire...

Top 10 Must Visit Places In Himachal Pradesh, India

Himachal Pradesh, in India, is a picture-perfect state that impresses tourists with scenic hill stations, quaint villages, snow-covered mountains, lush valleys, diverse flora and fauna,...

Here Is the Kind of Internet Connection That You Need for Your Browsing

For household and commercial use, everyone is looking out for the best internet connection. The internet has immensely evolved with time, and a need...

Here’s How Dinosaurs Caused Mammals to Develop Night Vision

By JoEllen McBride When dinosaurs ruled the earth, life was tough for our mammalian ancestors. So they learned to hunker down during the day and...

Recent Comments

Donate to NewsGram to support quality journalism.
x