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The study, published in the journal Genome Medicine, used artificial intelligence (AI) to examine genetic signatures of Crohn's disease in 111 people. Pixabay

Researchers have developed a new method that may help improve understanding and treatment of Crohn’s disease, which causes inflammation in digestive tract.

The study, published in the journal Genome Medicine, used artificial intelligence (AI) to examine genetic signatures of Crohn’s disease in 111 people.


The method can help in revealing previously undiscovered genes linked to the disease, and in predicting whether thousand others had the disease.

“Our method is not a clinical diagnosis tool, but it generates interesting observations that need to be followed up,” said senior author Yana Bromberg, Associate Professor at Rutgers University in the US.


Researchers have developed a new method that may help improve understanding and treatment of Crohn’s disease, which causes inflammation in digestive tract. Pixabay

“Further experimental work could reveal the molecular reasons behind some forms of Crohn’s disease and, potentially, lead to its better treatment,” Bromberg said.

Crohn’s disease affects around 780,000 people in the US.

Chronic inflammation may occur in any part of the gastrointestinal tract, although symptoms may occur elsewhere. It can also cause joint pain and skin problems, and children with the disease may have growth problems, according to the US National Library of Medicine.

The research team evaluated genetic variants in the 111 people, including 64 with Crohn’s disease, and used AI techniques to pinpoint genes whose functions changed more in Crohn’s patients than in healthy people, and vice versa.

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While the model’s accuracy might improve by including more people, it could help reveal the origin of Crohn’s disease and improve early diagnosis, the study said. “We can use the knowledge gained from this study to similarly model other genetically-linked diseases,” Bromberg said. (IANS)


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The aim of the book is to teach children that families can exist in different forms, and show them how to accept the diversity in family backgrounds.

By Siddhi Jain

Delhi-based author Pritisha Borthakur is set to release her new book, 'Puhor and Niyor's Mural of Family Stories'. The 1,404-word children's book was put together to address a new kind of societal debacle in the family system. The author says the aim is to teach children that families can exist in different forms, and show them how to accept the diversity in family backgrounds.

The author who named the book after her twin sons -- Puhor and Niyor -- is a parent who has seen and heard the tales of ridicule and discrimination suffered by many in India and beyond. She says the book is an artistic illustration for kids that details how different families can live and coexist. Whether it's children with two dads or two moms, children with a single dad or single mom, and even multiracial family units, Borthakur's book teaches love, understanding, and compassion towards unconventional families.

Beyond race, gender, color, and ethnicity which have formed the bases for discrimination since the beginning of time, this book aims to bring to light a largely ignored issue. For so long, single parents have been treated like a taboo without any attempt to understand their situations; no one really cares how or why one's marriage ended but just wants to treat single parents as villains simply for choosing happiness and loving their children.

Homosexual parents, a relatively new family system, is another form that has suffered hate and discrimination for many years. Pritisha emphasizes the need to understand that diversity in people and family is what makes the world beautiful and colourful. 'Puhor and Niyor's Mural of Family Stories' is a firm but compassionate statement against all forms of discrimination on the bases of sexual identity, gender, race, and even differences in background

four children standing on dirt during daytime 'Puhor and Niyor's Mural of Family Stories' is a firm but compassionate statement against all forms of discrimination on the bases of sexual identity, gender, race and even differences in background. | Photo by Ben Wicks on Unsplash


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