Saturday December 7, 2019

New Reusable Device Which can Help Women with Breast Cancer in Lower-Income Countries

Innovation in cancer care doesn't always mean that you have to create an entirely new treatment

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Breast Cancer, Device, Women
According to the study published in the journal PLOS One, the research team wanted to create a tissue-freezing tool that uses carbon dioxide. Pixabay

Researchers have developed a new reusable device which can help women with breast cancer in lower-income countries by using carbon dioxide, a widely available and affordable gas, to power a cancer tissue-freezing probe instead of industry-standard argon.

According to the study published in the journal PLOS One, the research team wanted to create a tissue-freezing tool that uses carbon dioxide, which is already widely available in most rural areas thanks to the popularity of carbonated drinks.

“Innovation in cancer care doesn’t always mean that you have to create an entirely new treatment. Sometimes it means radically innovating on proven therapies such that they’re redesigned to be accessible to the majority of the world’s population,” said the study’s first author Bailey Surtees from the Johns Hopkins University.

For the study, the research team tested their tool in three experiments to ensure it could remain cold enough in conditions similar to the human breast and successfully kill tumour tissues.

Breast Cancer, Device, Women
Researchers have developed a new reusable device which can help women with breast cancer in lower-income countries by using carbon dioxide. Pixabay

In the first experiment, the team used the tool on jars of ultrasound gel, which thermodynamically mimics human breast tissue, to determine whether it could successfully reach standard freezing temperatures killing tissues and form consistent iceballs.

In all the trials, the device formed large enough iceballs and reached temperatures below -40 degrees Celsius, which meets standard freezing temperatures for tissue death for similar devices in the United States.

For the second experiment, the team treated 9 rats with 10 mammary tumours. Afterwards, they looked at the tissues under a microscope and confirmed that the tool successfully killed 85 per cent or more tissues for all tumours.

Finally, the team tested the tool’s ability to reach temperatures cold enough for tissue destruction in the normal liver of a pig, which has a temperature similar to a human breast.

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The device was successfully able to stay cold enough during the entire experiment to kill the target tissue. (IANS)

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Females Suffering Domestic Abuse More Prone to Long-Term illness: Study

The study, examined the general practitioner (GP) records dating between 1995 and 2017 of 18,547 women who had suffered domestic abuse

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Domestic Abuse
According to the study, survivors of Domestic Abuse can experience immense physiological and psychological stress. Pixabay

Female survivors of Domestic Abuse are at double the risk of developing long-term illnesses that cause widespread bodily pain and extreme tiredness, a new study suggests.

Published in the Journal of Interpersonal Violence, the research from Universities of Birmingham and Warwick in the UK shows that women who have experienced domestic abuse are almost twice as likely to develop fibromyalgia and chronic fatigue syndrome (CFS) than those who have not.

Fibromyalgia causes pain all over the body, while CFS is an illness with a wide range of symptoms, most common of which is extreme tiredness. They are both long-term conditions.

“We have been aware that domestic abuse has significant negative effects for victims and their children. This and other related work by our team showing strong associations with several diseases suggests that the costs of abuse are even greater than understood previously,” said Indian-origin researcher and study co-author Siddhartha Bandyopadhyay from the University of Birmingham.

“The higher incidence of long-term illnesses, such as chronic fatigue syndrome, for abused women implies the existence of an additional hidden cost to society that we need to understand better,” Bandyopadhyay added.

The study, examined the general practitioner (GP) records dating between 1995 and 2017 of 18,547 women who had suffered domestic abuse, compared to 74,188 who had not.

They found the risk of developing fibromyalgia and CFS in women who have experienced domestic abuse was twice the rate of those who had no recorded experience by their GP, after taking into account factors which may influence the association.

The incidence rate ratio for developing fibromyalgia was 1.73 (1.36-2.22). The incidence rate ratio of developing CFS was 1.91 (1.11-3.33)

Domestic Abuse
Female survivors of Domestic Abuse are at double the risk of developing long-term illnesses that cause widespread bodily pain and extreme tiredness, a new study suggests. Pixabay

It comes after a previous study led by the University of Birmingham showed that UK domestic abuse victims are three times more likely to develop severe mental illnesses.

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“Considering the prevalence of domestic abuse, and the fact that patients experiencing fibromyalgia and CFS often face delays in diagnosis due to a limited understanding generally of how these conditions are caused, it is important for clinicians to bear in mind that women who have survived abuse are at a greater risk of these conditions,” Chandan added.

According to the study, survivors of Domestic Abuse can experience immense physiological and psychological stress. (IANS)