Thursday September 20, 2018

New test may prevent antibiotic resistances from spreading

Thereby, physicians would hold a powerful tool from which they could benefit in personalised therapy -- this means the administration of a fitting drug, the researchers said

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Overuse of Antibiotic pills has resulted in development of drug resilient bacterias,, Pixabay
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  • Scientists have found a new kind of test
  • This may prevent antibiotic resistance
  • The new method also provides faster diagnosis

Scientists have developed a new “rapid test” that produces a cheaper and faster diagnosis of infectious diseases in just three hours thus preventing antibiotic resistance from spreading.

Owing to small number of pathogens in a patient’s sample, standard practices require up to 72 hours to allow for a reliable result for the infectious diagnostics. The new method provides much faster diagnosis with the help of tiny electrodes that are fixed on the surface of a stamp-sized chip.

Drug overdose
This new test will stop antibiotic resistance. Pixabay

“Electric fields secure bacteria in a very small area,” said Ute Neugebauer from the Friedrich Schiller University Jena in Germany. The scientists then apply various antibiotics in different concentrations on the trapped bacteria and examine them with Raman spectroscopy.

“This means that we irradiate the pathogens with laser light and evaluate the scattered light spectrum”, Neugebauer said. “We combine light-based analytical methods with microfluidic sample processing. With our Lab-on-a-Chip system, thus a miniaturised lab, we are able to clearly identify bacterial strains and their resistances, in less than three hours,” he explained.

Also Read: Asthma Afflicted Children Are Prescribed Unwanted Antibiotics: Study

The combination of fast, light-based diagnostics and a high automation level reduces the time from sampling to result from to date 72 to three and a half hours.

The doctors can then derive whether the strain is resistant or sensible. At the same time they can also derive information on the needed concentration of the antibiotic to constrain bacterial growth.

The test will also lead to faster diagnosis. Wikimedia Commons
The test will also lead to faster diagnosis. Wikimedia Commons

“This is an important diagnostic parameter that influences the success of a treatment decidedly…such a fast procedure could revolutionise diagnostics of infectious diseases”, the researchers said, in a paper published in the journal Analytical Chemistry.

Another, more far-reaching, the aim is the further development of a cartridge-based rapid test system, which will enable general practitioners to identify resistances in a fast and easy way for the first time. Thereby, physicians would hold a powerful tool from which they could benefit in personalised therapy — this means the administration of a fitting drug, the researchers said. IANS

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Researchers In China Discover a Potential Antibiotic

Further tests are needed to see whether the substance is safe and effective to use as a drug against bacterial infections.

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Antibiotic
Chinese researchers identify potential new antibiotic. Pixabay

A fungal compound has been identified by a team of Chinese researchers as a promising antibiotic candidate, as they presented an approach that can efficiently obtain it the lab, said a study recently published in the journal Nature Communication.

Health organisations across the world are trying to reduce the use of antibiotics. Because the overuse of antibiotics in recent years means they’re becoming less effective and has led to the emergence of “superbugs” — strains of bacteria that have developed resistance to many different types of antibiotics, Xinhua news agency reported.

Antibiotic
Health organisations across the world are trying to reduce the use of antibiotics. Pixabay

Meanwhile researchers are working hard to find new antibiotics.

A team, led by researchers at China’s Chongqing University, has developed a technique to synthesize albomycins, a group of fungal compounds that have previously shown antimicrobial properties. The authors were able to obtain the substances in large enough amounts to allow them to test their antibiotic activity.

One substance performed well in a test against a variety of bacterial strains. Notably, it outperformed several established antibiotics.

Antibiotic
Misuse of antibiotic drugs have lead to the threat of antimicrobial resistance, Pixabay

Also Read: Weight Loss Tip- Chinese Medicine Ingredient May Help Reduce Obesity

“The method we use can efficiently and conveniently synthesize albomycins substances, and initial animal lab test has demonstrated that these substances are safe, but we will continue our research on its safety,” said Yun He, Lead Author of the study.

Further tests are needed to see whether the substance is safe and effective to use as a drug against bacterial infections, according to the team. (IANS)