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New test to detect ‘Ebola virus’ infection within minutes

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New York: In a major development in the fight against the deadly Ebola virus, a new test has been shown to accurately detect within minutes if an individual is infected by the virus.

This new rapid diagnostic test (RDT) could cut back on the lengthy process usually required to confirm if a patient has Ebola Virus Disease (EVD) or not, help identify case contacts and ultimately curb the spread of Ebola, said the study published in the journal, The Lancet.

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The study is the first to show that a point-of-care EVD test (ReEBOV Antigen Rapid Test; Corgenix) is faster  and as sensitive as a conventional laboratory-based molecular method used for clinical testing during the recent outbreak in Sierra Leone.

“Laboratory results can sometimes take days. Delays like this, result not only in the failure to diagnose and treat Ebola-infected patients, but also in individuals without Ebola being admitted to holding units where they may be subsequently infected with the virus,” said senior study author Nira Pollock from Boston Children’s Hospital, US.

“This test, on the other hand, is capable of detecting the Ebola virus in just a small drop of blood tested at the bedside and could help us in the fight against Ebola.”

Currently, diagnosis of EVD requires a full vial of venous blood to be shipped to a laboratory with a high level of biosafety and staff expertise for testing by real-time Reverse Transcription Polymerase Chain Reaction (RT-PCR).

In this study, researchers compared the diagnostic accuracy of the new RDT against the benchmark RT-PCR test (altona Diagnostics) being used for clinical diagnosis in the field reference laboratory run by Public Health England at Port Loko in Sierra Leone.

The study involved 106 suspected Ebola patients admitted to two treatment centres in Sierra Leone during February 2015 who were tested by both RDT (performed on a finger stick blood sample at the point-of-care) and by standard RT-PCR (performed on plasma in the laboratory).

The rapid diagnostic test detected all confirmed cases of EVD that were found positive by the benchmark method, with sensitivity of 100 percent (identifying all patients with EVD as per the benchmark method) and a specificity of 92 percent (identifying patients who did not have EVD).

(IANS)

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Lowering The Community Resistance To Ebola Is Extremely Important: UNICEF

In its latest assessment, the World Health Organization counted 197 confirmed and probable cases, including 92 deaths.

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Photo taken Sept 9, 2018, shows health workers walking with a boy suspected of having the Ebola virus at an Ebola treatment centre in Beni, Eastern Congo. VOA

The U.N. Children’s Fund (UNICEF) says it is increasing Ebola prevention efforts in eastern Democratic Republic of Congo. The agency says community resistance to efforts to contain Ebola is growing and must be fought to stop the spread of the fatal disease.

Since the disease outbreak was declared on August 1 in Congo’s North Kivu and Ituri provinces, UNICEF has been working with communities to inform them about how the virus spreads and what measures to take to protect themselves from being infected.

The U.N. agency is working with community and religious leaders in the city of Beni, where health workers are facing hostility and resistance. UNICEF spokesman Christophe Boulierac said the spread of false rumors and fear about Ebola are endangering efforts to contain the virus.

Ebola
Congolese health workers register people and take their temperatures before they are vaccinated against Ebola in the village of Mangina in North Kivu province of the Democratic Republic of Congo. VOA

“We are working with anthropologists, particularly in this Beni neighborhood, who ensure that the response is sensitive to cultural beliefs and practices, particularly around caring for sick and diseased individuals, and addressing population concerns about secure and dignified burials,” he said.

Boulierac said UNICEF is expanding its community outreach program to support thousands of people at risk in the city of Butembo. Two new Ebola cases recently were confirmed in this important commercial center with nearly one million inhabitants.

He said UNICEF is deploying a team of 11 specialists in community communication, education and psycho-social assistance. The agency also will provide water, sanitation and hygiene to help contain the disease and avoid further spread of the epidemic.

Congo,ebola
A Congolese health worker administers Ebola vaccine to a boy who had contact with an Ebola sufferer in the village of Mangina in North Kivu province of the Democratic Republic of the Congo. VOA

In its latest assessment, the World Health Organization counted 197 confirmed and probable cases, including 92 deaths.

Also Read: North Kivu And Ituri, Congo To Welcome More Than 80,000 Children In This New School Year

The outbreak in the DRC is the 10th since Ebola was first identified in 1976. (VOA)