Tuesday March 19, 2019

New Wearable Patch Sensor to Boost Diagnosis for Heart Rhythm Disorder

The participants self-applied the wearable sensor patch for two weeks and returned it for analysis

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heart disease
Representational image. (IANS)

A wearable patch that acts like a sensor can effectively improve the diagnosis rate for heart rhythm disorder without interfering with routine activities, scientists have found.

Atrial fibrillation (Afib) disorder, is characterised by increased or irregular heart rhythm that increases the risk of stroke, heart failure and other cardiovascular diseases.

The US Food and Drug Administration (FDA) approved wearable patch acts like a sensor and performs active electrocardiography (ECG) screening to detect irregular heart rhythm condition as well as recent heart attacks.

The device resulted in more people receiving critical preventive therapies, which might have gone undiagnosed, said the researchers while emphasising the use of digital medicine technologies to identify undiagnosed Afib disorder in at-risk populations.

“Our study shows an almost threefold improvement in the rate of diagnosis of AFib in the those actively monitored compared to usual care,” said Steven Steinhubl, Director of digital medicine at Scripps Translational Science Institute (STSI) in California, US.

heart beat rate
Atrial fibrillation (Afib) disorder, is characterised by increased or irregular heart rhythm that increases the risk of stroke, heart failure and other cardiovascular diseases. Pixabay

“Timely diagnosis of AFib more effectively can enable the initiation of effective therapies and help reduce strokes and death,” added Steinhubl, who is also a professor at Scripps Research Institute in the US.

The study, published in the journal JAMA, included data from 5,214 individuals for one year, with one third of the group being assigned to the monitored cohort and the rest being observational controls.

The participants self-applied the wearable sensor patch for two weeks and returned it for analysis.

Also Read: Stem Cell Thearpy To Treat Heart-Failure

The team found that six per cent of the group developed Afib and nearly three per cent among the controls developed the disease.

“This study demonstrates the utility of a digital approach not only to diagnosing asymptomatic AFib, but to the clinical research field as a whole,” Steinhubl explained. (IANS)

Next Story

Gene Therapy Can Help Correct Heart Rhythm Disorder

However, considerable research is still needed before a treatment can be arrived at that is suitable for human patients

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genes
The study modified the levels of the protein encoded by a single gene known as GPR39.  Pixabay

A novel gene therapy uses an implanted LED device to reset a racing heart immediately and automatically, paving the way for pain-free treatment for patients with heart rhythm disorder.

The therapy detects fast arrhythmias in the atrium of a rat’s heart and sends a signal to a LED device placed near the heart.

“The flash of light from this LED then causes the heart to generate an electric current itself to halt the arrhythmia,” said lead investigator Daniel Pijnappels at Leiden University in the Netherlands.

“This is made possible by using gene therapy to introduce specific light-sensitive proteins into the heart. This restores the heart’s normal rhythm immediately and automatically,” he added.

According to the researchers, this could represent a great improvement on the current way of stopping atrial fibrillation.

The heart attack brings about activation of certain genes which stay as a permanent memory in genes. Pixabay

Atrial fibrillation is the most common heart rhythm disorder in clinical practice. The current treatment, known as cardioversion, is based on administering an electric shock to the heart, which has to be done in the hospital under general anaesthesia because of pain.

For many patients, this is the only treatment to immediately stop atrial fibrillation because drugs or an operation are ineffective.

“The bioelectronic defibrillator can stop atrial fibrillation without an electrical shock. In this way, the heart can be reset in a fully automated manner and at any time,” Pijnappels said, in the paper reported in the journal Science Translational Medicine.

Also Read- Novel Treatment Offers Promise to Stop Parkinson’s

“We anticipate that this treatment for atrial fibrillation could improve both the patient’s quality of life and their prognosis,” he added.

However, considerable research is still needed before a treatment can be arrived at that is suitable for human patients, the researchers noted. (IANS)