Friday September 21, 2018

Night shifts may increase cancer risk

A positive association between night shifts and risk of cancer

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Night shifts increase cancer risk. Pexels
Night shifts increase cancer risk. Pexels
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  • Long-term night shift work among women increased the risk of cancer by 19%.
  • A meta-analysis using using international data from 61 articles comprising 114,628 cancer cases and 3,909,152 participants.
  • These studies found an association between long-term night shift work and risk of 11 types of cancer.

Women who work overnight have a comparatively high risk of developing cancer than women who do not, say researchers. An analysis of international data has confirmed an association between night-shifts and cancer.

“Our study indicates that night shift work serves as a risk factor for common cancers in women,” said Xuelei Ma, co-author of the study from West China Medical Center of Sichuan University in Chengdu, China.

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Findings

These studies found an association between long-term night shift work and risk of 11 types of cancer. Wikimedia commons
These studies found an association between long-term night shift work and risk of 11 types of cancer. Wikimedia commons
  • Long-term night shift work among women increased the risk of cancer by 19 percent.
  • Nurses (working in night shifts) had the highest risk of breast cancer, of all the occupations analysed.
  • The population of women working on night shifts have an increase risk of skin (41%), breast (32%) and gastrointestinal cancer (18%).
  • Among female nurses alone, those who worked the night shift had an increased risk of breast (58%), gastrointestinal (35%) and lung cancer (28%).

Methodology

  • A meta-analysis using data from 61 articles comprising 114,628 cancer cases and 3,909,152 participants from North Amercia, Europe, Australia and Asia.
  • The articles consisted of 26 cohort studies, 24 case-control studies and 11 nested case-control studies.
  • These studies found an association between long-term night shift work and risk of 11 types of cancer.

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“Nurses that worked the night shift were of a medical background and may have been more likely to undergo screening examinations,” the researcher suggested.

The results might help establish and implement effective measures to protect female night shifters. Pixabay
The results might help establish and implement effective measures to protect female night shifters. Pixabay

“Long-term night shift workers should have regular physical examinations and cancer screenings,” Ma noted.

The study was published in journal Cancer Epidemiology. (IANS)

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Gut Microbiota Can Help Identify Liver Cancer: Researchers

Gut microbiota can help the body digest certain foods that the stomach and small intestine have not been able to digest.

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Liver Cancer
How gut microbiota can aid in early diagnosis of liver cancer.

Chinese researchers have identified gut microbiota as a new biomarker of liver cancer, that can help in early diagnosis as well as treatment of the condition.

Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the third leading cause of cancer-related death worldwide.

Due to the absence of specific symptoms in early stages and the lack of diagnostic markers, most patients with HCC are often diagnosed in an advanced stage.

Liver Cancer
AFP is a plasma protein that is produced in abundance by the liver cells. Pixabay

Researchers from China’s Zhejiang University, and Zhengzhou University, found that the microbial diversity in patients with cirrhosis was significantly lower than that in healthy people, but it increased when cirrhosis develops into cancer, the Xinhua reported.

Human gut microbiota has been considered the most important micro-ecosystem living with the body, containing tens of trillions of microorganisms, including at least 1,000 species of bacteria with more than 3 million genes.

Gut microbiota can help the body digest certain foods that the stomach and small intestine have not been able to digest.

Liver Cancer
A high-magnification image from a 2012 glioblastoma case is seen as an example in this College of American Pathologists image released from Northfield. VOA

For the study, appearing in the journal Gut, the team collected 486 fecal samples from across the country.

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About 12 bacteria genera decreased and six increased in patients with early cancer compared with healthy people.

According to researchers, more data and further studies are needed to confirm the validity and reliability of the model. (IANS)