Tuesday September 25, 2018

According to Research, No Exercise For 6 Years Can Trigger Heart Failure Risk

Too busy or lazy to exercise? Men and women take note. Living without physical activity for six years during their middle age could be at an increased risk of suffering heart failure, researchers have warned.

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Too busy or lazy to exercise? Men and women take note. Living without physical activity for six years during their middle age could be at an increased risk of suffering heart failure, researchers have warned.

The findings, described in the journal Circulation, suggest that consistently participating in the recommended 150 minutes of moderate to vigorous activity each week, such as brisk walking or biking, in middle age can reduce the heart failure risk by 31 per cent.

While it is known that people who are more physically active have lower risks of heart failure than those who are less active, but little is known about the impact of changes in exercise levels over time on heart failure risk.

Heart
representational image. pixabay

 

“Going from no exercise to recommended activity levels over six years in middle age may reduce heart failure risk by 23 per cent,” said Chiadi Ndumele, Assistant Professor at the Johns Hopkins University in Maryland, US.

For the study, the team included 11,351 participants, with an average age 60, monitored annually for an average of 19 years.

According to the American Heart Association, the “recommended” amount is at least 75 minutes per week of vigorous intensity or at least 150 minutes per week of moderate intensity exercise.

Heart failure risk decreased by about 12 per cent in the participants who increased their physical activity category from poor to intermediate or recommended, or from intermediate to recommended, compared with those with consistently poor or intermediate activity ratings.

Representational image.
Heart failure risk decreased by about 12 percent of the participants who increased their physical activity. Pixabay

Conversely, heart failure risk increased by 18 percent in the participants who reported decreased physical activity from visit one to visit three, compared with those with consistently recommended or intermediate activity levels.

Unlike the heart attack, in which heart muscle dies, heart failure is marked by a long-term, chronic inability of the heart to pump enough blood, or pump it hard enough, to bring needed oxygen to the body.

Also Read: Drug Used For Osteoporosis May Help in Reducing Heart Attack Risk

The leading cause of hospitalizations in those over 65, the disorder’s risk factors include high blood pressure, high cholesterol, diabetes, smoking and a family history. (IANS)

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Learn How Muscles Help Burn Fat During Exercise

Burning fat is likely to impact multiple aspects of metabolic health related to diabetes, heart disease and other conditions

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Further research revealed that BAIBA levels rise during exercise and are inversely associated with metabolic risk factors. Pixabay

Ever thought what helps burn fat across your body while exercising? According to a study, it is a molecule in our muscles that is produced during exercise and contributes to the beneficial effects of exercise on metabolism.

“Our finding bolsters the underlying notion that signals generated in exercising muscle are released into the circulation and influence other tissues such as fat cells and liver,” said senior author Robert Gerszten at Massachusetts General Hospital, the primary teaching hospital of Harvard Medical School.

The researchers knew that a protein called PGC-1? regulates metabolic genes in muscle and contributes to the response of muscle to exercise.

But how this protein conveys signals to other tissues was unclear so far.

Gerszten and his colleagues forced the expression of PGC-1? in muscle cells and then looked for metabolites that were secreted from the cells.

Exercise
BAIBA also decreased weight gain and helped balance blood sugar levels in mice, said the study published in the journal Cell Metabolism. Pixabay

They identified ?-aminoisobutyric acid (BAIBA) as one such metabolite and found that it increased fat cells’ expression of genes that are involved with burning calories.

BAIBA also decreased weight gain and helped balance blood sugar levels in mice, said the study published in the journal Cell Metabolism.

Further research revealed that BAIBA levels rise during exercise and are inversely associated with metabolic risk factors.

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“The findings suggest that BAIBA may contribute to exercise-induced protection from metabolic diseases. Manipulating BAIBA – or enzymes that generate BAIBA – may have therapeutic potential,” said Gerszten.

Burning fat is likely to impact multiple aspects of metabolic health related to diabetes, heart disease and other conditions, the study concluded.  (IANS)