Tuesday January 22, 2019

Obese? Blame it on Fat Cells’ Expansion

According to researchers, the mechanics of 'cellular expansion' plays a pivotal role in fat production

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Obese? Blame it on Fat Cells' Expansion
Obese? Blame it on Fat Cells' Expansion. VOA

You have heard about obesity or accumulation of fat but do you know that nutrition is not the only factor driving obesity in our kids?

According to researchers, the mechanics of ‘cellular expansion’ plays a pivotal role in fat production.

To understand how obesity develops, a team from Tel Aviv University in Israel used state-of-the-art technology to analyse the accumulation of fat in the body at the cellular level.

“We wanted to find out why a sedentary lifestyle results in obesity, other than making time to eat more hamburgers,” said professor Amit Gefen from Tel Aviv University’s department of biomedical engineering.

“We found that fat cells exposed to sustained, chronic pressure – such as what happens to the buttocks when you are sitting down – experienced accelerated growth of lipid droplets, which are molecules that carry fats,” Gefen added.

Contrary to muscle and bone tissue, which get mechanically weaker with disuse, fat depots in fat cells expanded when they experienced sustained loading by as much as 50 percent. This was a substantial discovery.

The researchers discovered that, once it accumulated lipid droplets, the structure of a cell and its mechanics changed dramatically.

obesity
Representational image. Pixabay

Using a cutting-edge atomic force microscope and other microscopy technologies, they were able to observe the material composition of the transforming fat cell, which became stiffer as it expanded.

This stiffness alters the environment of surrounding cells by physically deforming them, pushing them to change their own shape and composition.

“When they gain mass and change their composition, expanding cells deform neighbouring cells, forcing them to differentiate and expand,” he explained.

Also Read: Kids Who Sleep Less Eat More

This proves that you are not just what you eat. You are also what you feel – and what you are feeling is the pressure of increased weight and the sustained loading in the tissues of the buttocks of the couch potato.

If you can learn to control the mechanical environment of cells, you can then determine how to modulate the fat cells to produce less fat, Natan Shaked from Tel Aviv University noted.

The team is now creating a platform to develop new therapies and technologies to prevent or even reverse fat gain, said the research published in the Biophysical Journal. (Bollywood Country)

Next Story

Obesity Can Shorten Your Dog’s Lives

"For many owners, giving food, particularly tasty table scraps and tidbits, is the way we show affection for our pets," German said

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A Labrador retriever named Jack dines at a pet restaurant in San Juan, Manila, Philippines, Sept. 6, 2014.
Obesity can cut short your dog's lives. VOA

If you thought that obesity affects only humans, you may be wrong. It can also shorten lives of your canine friends, finds a research.

The research, from the University of Liverpool in the UK, reveals that the lifespan of overweight dogs was up to two-and-half years shorter when compared to ideal-weight dogs.

“Owners are often unaware that their dog is overweight, and many may not realise the impact that it can have on their health,” said Alex German, Professor at the university.

“What they may not know is that if their beloved pet is too heavy, they are more likely to suffer from other problems such as joint disease, breathing issues, and certain types of cancer, as well as having a poorer quality of life. These health and well-being issues can significantly impact how long they live,” he added.

The study, published in the Journal of Veterinary Internal Medicine, examined more than 50,000 dogs across 12 of the most popular dog breeds.

The results showed that the pups' attractiveness was lowest at birth and increased to a maximum before 10 weeks of age before declining and then levelling off.
Representational Image. pixabay

Although the study did not examine the reasons behind the extra pounds in dogs, feeding habits are thought to play a role in pet obesity.

According to a recent Better Cities For Pets survey, more than half (54 per cent) of cat and dog owners always or often give their pet food if they beg for it, and nearly a quarter (22 per cent) of cat and dog owners sometimes overfeed their pet to keep them happy.

Also Read- Actor Aamir Khan Feels Necessity To Guide Children on Good Lifestyle Habits

“For many owners, giving food, particularly tasty table scraps and tidbits, is the way we show affection for our pets,” German said.

“Being careful about what you feed your dog could go a long way to keeping them in good shape and enabling them to be around for many years to come,” he noted. (IANS)