Wednesday March 20, 2019

Obese? Blame it on Fat Cells’ Expansion

According to researchers, the mechanics of 'cellular expansion' plays a pivotal role in fat production

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Obese? Blame it on Fat Cells' Expansion
Obese? Blame it on Fat Cells' Expansion. VOA

You have heard about obesity or accumulation of fat but do you know that nutrition is not the only factor driving obesity in our kids?

According to researchers, the mechanics of ‘cellular expansion’ plays a pivotal role in fat production.

To understand how obesity develops, a team from Tel Aviv University in Israel used state-of-the-art technology to analyse the accumulation of fat in the body at the cellular level.

“We wanted to find out why a sedentary lifestyle results in obesity, other than making time to eat more hamburgers,” said professor Amit Gefen from Tel Aviv University’s department of biomedical engineering.

“We found that fat cells exposed to sustained, chronic pressure – such as what happens to the buttocks when you are sitting down – experienced accelerated growth of lipid droplets, which are molecules that carry fats,” Gefen added.

Contrary to muscle and bone tissue, which get mechanically weaker with disuse, fat depots in fat cells expanded when they experienced sustained loading by as much as 50 percent. This was a substantial discovery.

The researchers discovered that, once it accumulated lipid droplets, the structure of a cell and its mechanics changed dramatically.

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Representational image. Pixabay

Using a cutting-edge atomic force microscope and other microscopy technologies, they were able to observe the material composition of the transforming fat cell, which became stiffer as it expanded.

This stiffness alters the environment of surrounding cells by physically deforming them, pushing them to change their own shape and composition.

“When they gain mass and change their composition, expanding cells deform neighbouring cells, forcing them to differentiate and expand,” he explained.

Also Read: Kids Who Sleep Less Eat More

This proves that you are not just what you eat. You are also what you feel – and what you are feeling is the pressure of increased weight and the sustained loading in the tissues of the buttocks of the couch potato.

If you can learn to control the mechanical environment of cells, you can then determine how to modulate the fat cells to produce less fat, Natan Shaked from Tel Aviv University noted.

The team is now creating a platform to develop new therapies and technologies to prevent or even reverse fat gain, said the research published in the Biophysical Journal. (Bollywood Country)

Next Story

Research Reveals: It’s Your Friend’s Company That Can Turn You Obese

Social contagion in obesity means if more people around you are obese, then that may increase your own chances of becoming obese.

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Unhealthy food promotes obesity. pixabay

Besides genes and an unhealthy diet, your friends can also play a role in making you overweight, says a study, which found that obesity can spread through communities like a ‘social contagion’.

The study showed social circles can influence a person to become obese, suggesting the risk of becoming overweight increases if one moves to an area with a high rate of obesity, the Daily Mail reported.

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On the other hand, the risk of the parent becoming obese or overweight went up five per cent for increase in every one per cent of obesity in the area. Pixabay

“Social contagion in obesity means if more people around you are obese, then that may increase your own chances of becoming obese. Subconsciously, you are affected by what people around you are doing,” said Ashlesha Datar at the University of Southern California.

“If you move to a community where a sedentary lifestyle is the norm, you join that. There is this social influence,” Datar said.

For the study, the team included 1,314 parents and 1,111 children of US Army personnel at 38 bases.

The chances of becoming overweight or obese for a teenager increased four-six per cent for rise in every one per cent in the obesity.

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If you move to a community where a sedentary lifestyle is the norm, you join that. There is this social influence,” Datar said. Pixabay

On the other hand, the risk of the parent becoming obese or overweight went up five per cent for increase in every one per cent of obesity in the area.

Also Read: Authorities Scroll Through Social Media Violations Of Laws Restricting Political Parties, As It Forms Thailand’s Election “War Room”

The longer the families lived there, the more likely they put on weight, the report said.

Obesity can be caused by many variables, and previous research has shown living in certain communities carries a higher risk of obesity than living in other communities. (IANS)