Obese? Blame it on Fat Cells’ Expansion

According to researchers, the mechanics of 'cellular expansion' plays a pivotal role in fat production

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Obese? Blame it on Fat Cells' Expansion
Obesity may alter 70% routine blood tests in kids: Study. VOA

You have heard about obesity or accumulation of fat but do you know that nutrition is not the only factor driving obesity in our kids?

According to researchers, the mechanics of ‘cellular expansion’ plays a pivotal role in fat production.

To understand how obesity develops, a team from Tel Aviv University in Israel used state-of-the-art technology to analyse the accumulation of fat in the body at the cellular level.

“We wanted to find out why a sedentary lifestyle results in obesity, other than making time to eat more hamburgers,” said professor Amit Gefen from Tel Aviv University’s department of biomedical engineering.

“We found that fat cells exposed to sustained, chronic pressure – such as what happens to the buttocks when you are sitting down – experienced accelerated growth of lipid droplets, which are molecules that carry fats,” Gefen added.

Contrary to muscle and bone tissue, which get mechanically weaker with disuse, fat depots in fat cells expanded when they experienced sustained loading by as much as 50 percent. This was a substantial discovery.

The researchers discovered that, once it accumulated lipid droplets, the structure of a cell and its mechanics changed dramatically.

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Representational image. Pixabay

Using a cutting-edge atomic force microscope and other microscopy technologies, they were able to observe the material composition of the transforming fat cell, which became stiffer as it expanded.

This stiffness alters the environment of surrounding cells by physically deforming them, pushing them to change their own shape and composition.

“When they gain mass and change their composition, expanding cells deform neighbouring cells, forcing them to differentiate and expand,” he explained.

Also Read: Kids Who Sleep Less Eat More

This proves that you are not just what you eat. You are also what you feel – and what you are feeling is the pressure of increased weight and the sustained loading in the tissues of the buttocks of the couch potato.

If you can learn to control the mechanical environment of cells, you can then determine how to modulate the fat cells to produce less fat, Natan Shaked from Tel Aviv University noted.

The team is now creating a platform to develop new therapies and technologies to prevent or even reverse fat gain, said the research published in the Biophysical Journal. (Bollywood Country)

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Here’s How You Can Tackle Obesity And Stay Healthy During Lockdown

One needs to maintain good health during the time of lockdown

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Here's how you can deal with obesity during lockdown. Pixabay

The pandemic has contributed to an increase in obesity rates as weight loss programmes (which are often delivered in groups) and referred interventions such as surgery are being severely curtailed. We bring to you some Health Tips-

Importantly, the current crisis and the need for self-isolation is prompting many to rely on processed food with longer shelf life (instead of fresh produce) and canned food (with higher quantities of sodium). One might notice an increase in weight if this pattern of lifestyle persists for a longer period of time.

So what should a person do to stay healthy and make one stronger in these times? Dr Sharad Sharma, Laparoscopic and Bariatric Surgeon, Hiranandani Hospital, Vashi gives a few recommendations:

Proper nutrition and hydration are vital

Those who consume a well-balanced diet are healthier and are able to build stronger immune system. A healthy diet limits the risk of chronic illnesses and infectious diseases

It is recommended to eat a variety of fresh and unprocessed foods every day to accomplish the body’s requirement of necessary Vitamins, Minerals, Dietary Fiber, Proteins and Antioxidants

Consume whole grains and legumes – this also reduces the risk of Diabetes

Drink ample water � at least 5 liters per day

Avoid sugar, fat and salt to significantly lower your risk of being overweight, and obese

Do not consume sugar-sweetened beverages & limit intake of oily food

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One should avoid sitting for a long time and in every 20 minutes, move around for 3-5 minutes. Pixabay

Staying active

While the stay at home order has restricted our outdoor movements, it is important for people of all ages and abilities to be as active as possible.

Avoid sitting or slouching all the time

Every 20 minutes, move around for 3-5 minutes; walk or stretch-this will help reduce the strain on a muscle, relieve any form of mental tension and will help circulate blood to the body.

Read More: Understand Your Kids’ Perspective to Make Them Exercise

Muscle activity increases if you are physically active, reducing the risk of speedy weight gain.

More vigorous free exercises are also great ways to remain active at home.

In current times focusing on good health, food habits and maintaining some level of physical activity will go a long way in warding off obesity. (IANS)

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Can Depression Lead to Weight Gain? Find it Out Here

Risk of depression increases with higher weight: Study

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Researchers have found that the risk of depression increases with higher weight. Pixabay

Feeling depressed? Your weight might be the reason behind it as researchers have found that the risk of depression increases with higher weight.

The aim of this study, published in the journal Obesity analysis, was to describe the age and gender specific incidence of depression, the dosearesponse relationship between BMI (body mass index) and risk of depression and antidepressant drug prescribing in adults with overweight or obesity.

“Our findings highlight the complex relationship between depression and obesity,” said study lead author Freya Tyrer from the University of Leicester in the UK.

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Consuming anti-depressants can also lead to weight gain. Pixabay

“We would like to see tailored guidance on antidepressant prescribing and services that focus on both mood and behaviours to improve outcomes for these individuals,” Tyrer added.

Retrospective electronic health record study using the Clinical Practice Research Datalink was conducted to identify adults with overweight and obesity (below 18 years) with an incident of depression.

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In an analysis of primary care records of 519,513 UK adults who were overweight or obese between 2000-2016 and followed up until 2019, the incidence of new cases of depression was 92 per 10,000 people per year. The risk of depression also rose with higher weight, according to the study.

The study also found that antidepressants were prescribed in approximately two-thirds of adults who were overweight or obese.

Also Read- COVID-19 Crisis Affects Cultural Industry Negatively: UNESCO

Prescriptions for fluoxetine dropped over time (from 20.4 per cent in 2000 to 8.8 per cent in 2018) and prescriptions for sertraline increased (from 4.3 per cent in 2000 to 38.9 per cent in 2018).

“We recommend guidance on antidepressant drug prescribing and specific services for people with obesity and depression that address both symptoms and behaviours,” the researchers noted. (IANS)

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Consistent Bedtime Routine Reduces Risk of Obesity in Children

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Following a consistent bedtime routine may help reduce children's risk of becoming overweight or obese. Pixabay

Dear parents, kindly take note. Researchers have found that going to bed early and following a consistent bedtime routine may help reduce children’s risk of becoming overweight or obese.

“While we know it can be hard to get children to bed early, and at consistent times both on weekdays and at weekends, it might help parents or carers to know that establishing consistent and early bedtime may reduce the risk that their child will be overweight or obese,” said study lead author Yaqoot Fatima from the University of Queensland and James Cook University in Australia.

For the findings, published in the journal Acta Paediatrica, the research team wanted to explore sleep patterns in indigenous Australian children and assess the role of sleep timing in longitudinal changes in body mass index (BMI).In the study of 1,258 Indigenous Australian children were picked with an average age of 6 years.

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The findings highlight the importance of looking beyond sleep duration and highlighting the benefits of early bedtime for children. Pixabay

Latent profile analysis was conducted with the Australian Longitudinal Study of Indigenous Children (LSIC) cohort data, to determine distinct patterns of bed and wake timing, taking account of weekday sleep duration, weekday and weekend bedtimes, and weekday wake times.

Multilevel models with a random intercept were used to investigate the role of baseline sleep pattern in predicting longitudinal changes in BMI.

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The researchers found that children who consistently went to bed late experienced greater weight gain over several years than those who went to bed early.

Also Read- Know How Smoking Cigarettes at a Young Age Can be Harmful

The findings highlight the importance of looking beyond sleep duration and highlighting the benefits of early bedtimes for children.

“As sleep timing is modifiable, this offers the opportunity for improvement in sleep and protecting against future weight gain in indigenous children,” the researchers noted. (IANS)