Thursday April 25, 2019

Obesity During Pregnancy May up Kids’ Risk of Epilepsy

In addition, complications related to neonatal-asphyxia -- the state of being deprived of oxygen --, as well as less severe neonatal complications, were also independently associated with increased risk of childhood epilepsy

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Pregnancy, autism
Pregnancy after breast cancer does not increase a woman's risk of a relapse. Pixabay

Women who are overweight or obese during their pregnancy may significantly increase the risk for children developing epilepsy, a study has showed.

Epilepsy is a disorder in which nerve cell activity in the brain is disturbed, causing seizures.

The results showed that the risk of epilepsy increased by 11 per cent in children of overweight mothers (BMI of 25 to less than 30) compared with children and normal-weight mothers.

While women with grade I obesity (BMI 30 to less than 35) increased the risk 20 by per cent, those with grade II obesity (BMI 35 to less than 40) raised the risk by 30 per cent.

The risk for children with mothers in the grade III obesity category was 82 per cent.

Pregnancy
Representational image. Pixabay

“Given that overweight and obesity are potentially modifiable risk factors, prevention of obesity in women of reproductive age may be an important public health strategy to reduce the incidence of epilepsy,” said Neda Razaz, from the Karolinska Institutet in Sweden.

Maternal overweight and obesity may increase the risk of brain injury, leading to a range of neurodevelopmental disorders, or that maternal obesity might affect neurodevelopment through obesity-induced inflammation, leading to epilepsy, the researchers argued, in the article published online by JAMA Neurology.

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In addition, complications related to neonatal-asphyxia — the state of being deprived of oxygen –, as well as less severe neonatal complications, were also independently associated with increased risk of childhood epilepsy. (Bollywood Country)

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Avoid Smoking During Pregnancy To Prevent Premature Births

The negative health impacts of cigarette smoking during pregnancy, including low birth weight, delayed intrauterine development, pre-term birth, infant mortality, and long-term developmental delays, are well known. 

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smoking
The researcher plans to look at quit rates and smoking intensity and their impact on the risk of infant mortality. Pixabay

Expecting mothers, take note. As smoking during pregnancy is linked with negative health outcomes, a team of researchers has found that smoking cessation during pregnancy may reduce the risk of pre-term birth.

The findings, published in the JAMA Network Open journal, showed that the probability of pre-term birth decreased with earlier smoking cessation in pregnancy — up to a 20 per cent relative decrease if cessation occurred at the beginning of pregnancy.

baby
If we determine quitting, and quitting early, reduces the risk of infant mortality, then that may speak to mothers even more saliently about the importance of smoking cessation. Pixabay

“Of concern, though, given the substantial benefits of smoking cessation during pregnancy is that the proportion of pre-pregnancy smokers who quit smoking during pregnancy has remained essentially stagnant since 2011,” said lead author Samir Soneji from The Dartmouth Institute for Health Policy and Clinical Practice in the US.

For the study, the researchers conducted a cross-sectional study of more than 25 million pregnant women who gave birth to live neonates during a six-year period — measuring their smoking frequency three months prior to pregnancy and for each trimester during pregnancy.

The negative health impacts of cigarette smoking during pregnancy, including low birth weight, delayed intrauterine development, pre-term birth, infant mortality, and long-term developmental delays, are well known.

But the good news is that the proportion of women who start their pregnancy as smokers has been declining in recent years, the researchers said.

smoking

The findings, published in the JAMA Network Open journal, showed that the probability of pre-term birth decreased with earlier smoking cessation in pregnancy — up to a 20 per cent relative decrease if cessation occurred at the beginning of pregnancy. Pixabay

However, the study also found that only about 25 per cent of women who smoked prior to pregnancy were able to quit throughout their pregnancy, and approximately 50 per cent of women who smoked during their pregnancy did so with high frequency (more than 10 cigarettes per day).

The researcher plans to look at quit rates and smoking intensity and their impact on the risk of infant mortality.

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“Thankfully most premature babies end up doing well,” he said.

“But premature birth is strongly linked to infant mortality. If we determine quitting, and quitting early, reduces the risk of infant mortality, then that may speak to mothers even more saliently about the importance of smoking cessation,” he added. (IANS)