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A study has revealed that obesity may contribute toward neural tissue vulnerability while maintaining a healthy weight in mild Alzheimer's disease dementia could help to preserve brain structure. Unsplash

Being overweight is an additional burden on brain health and it may exacerbate Alzheimer’s disease, a new study suggests.

The study revealed that obesity may contribute toward neural tissue vulnerability while maintaining a healthy weight in mild Alzheimer’s disease dementia could help to preserve brain structure.


“More than 50 million people are thought to be living with Alzheimer’s disease and despite decades of groundbreaking studies and a huge global research effort we still don’t have a cure for this cruel disease,” said lead researcher Annalena Venneri, Professor at the University of Sheffield in the UK.

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For the study, the team examined MRI brain scans of 47 patients clinically diagnosed with mild Alzheimer’s disease dementia, 68 patients with mild cognitive impairment, and 57 cognitively healthy individuals.

The study, published in The Journal of Alzheimer’s Disease Reports, used three complementary, computational techniques to look at the anatomy of the brain, blood flow and also the fibres of the brain.

The international team compared multiple brain images and measured differences in local concentrations of brain tissues to assess grey matter volume — which degenerates during the onset of Alzheimers — white matter integrity, cerebral blood flow and obesity.


Being overweight is an additional burden on brain health and it may exacerbate Alzheimer’s disease, a new study suggests. Pinterest

In mild dementia patients, a positive association was found between obesity and grey matter volume around the right temporoparietal junction. This suggests obesity might contribute toward neural vulnerability in cognitively healthy individuals and those with mild cognitive impairment.

The study also found that maintaining a healthy weight in mild Alzheimer’s disease dementia could help preserve brain structure in the presence of age and disease-related weight loss.

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“We found that maintaining a healthy weight could help preserve brain structure in people who are already experiencing mild Alzheimer’s disease dementia. Unlike other diseases such as cardiovascular disease or diabetes, people don’t often think about the importance of nutrition in relation to neurological conditions, but these findings show it can help to preserve brain structure,” researcher Matteo De Marco from the varsity said. (IANS)


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The aim of the book is to teach children that families can exist in different forms, and show them how to accept the diversity in family backgrounds.

By Siddhi Jain

Delhi-based author Pritisha Borthakur is set to release her new book, 'Puhor and Niyor's Mural of Family Stories'. The 1,404-word children's book was put together to address a new kind of societal debacle in the family system. The author says the aim is to teach children that families can exist in different forms, and show them how to accept the diversity in family backgrounds.

The author who named the book after her twin sons -- Puhor and Niyor -- is a parent who has seen and heard the tales of ridicule and discrimination suffered by many in India and beyond. She says the book is an artistic illustration for kids that details how different families can live and coexist. Whether it's children with two dads or two moms, children with a single dad or single mom, and even multiracial family units, Borthakur's book teaches love, understanding, and compassion towards unconventional families.

Beyond race, gender, color, and ethnicity which have formed the bases for discrimination since the beginning of time, this book aims to bring to light a largely ignored issue. For so long, single parents have been treated like a taboo without any attempt to understand their situations; no one really cares how or why one's marriage ended but just wants to treat single parents as villains simply for choosing happiness and loving their children.

Homosexual parents, a relatively new family system, is another form that has suffered hate and discrimination for many years. Pritisha emphasizes the need to understand that diversity in people and family is what makes the world beautiful and colourful. 'Puhor and Niyor's Mural of Family Stories' is a firm but compassionate statement against all forms of discrimination on the bases of sexual identity, gender, race, and even differences in background

four children standing on dirt during daytime 'Puhor and Niyor's Mural of Family Stories' is a firm but compassionate statement against all forms of discrimination on the bases of sexual identity, gender, race and even differences in background. | Photo by Ben Wicks on Unsplash


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