Saturday July 21, 2018

Obesity Possess Threat of Progressive Disability for Patients of Rheumatoid Arthritis

The researchers found that severe obesity was associated with more rapid progression of disability.

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Overweight means having more body weight than is considered normal or healthy for one's age or build, while obesity is the condition of the excess amount of body fat with a body mass index (BMI) of over 30.
Representational Image, pixabay
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Obese patients with rheumatoid arthritis are more likely to experience progressive disability than patients who are overweight, according to a new study.

Overweight means having more body weight than is considered normal or healthy for one’s age or build, while obesity is the condition of the excess amount of body fat with a body mass index (BMI) of over 30.

The researchers found that severe obesity was associated with more rapid progression of disability.

Overweight means having more body weight than is considered normal or healthy for one's age or build, while obesity is the condition of the excess amount of body fat with a body mass index (BMI) of over 30.
Representational Image, Pexels

The study, published in the journal Arthritis Care and Research, also found that patients who lost weight tended to become disabled more quickly.

Health providers need to recognize unintentional weight loss as a poor prognostic sign and refer patients for strength training, physical therapy, and other interventions to prevent disability, said the researcher.

“We believe that this is because when people get older and acquire illness, they tend to lose weight,” said Joshua Baker of the Perelman School of Medicine at the University of Pennsylvania.

Also Read: Foetal Immune Rejection Could be the Reason of Preterm Labor 

“So, this study suggests that patients with rheumatoid arthritis and obesity would benefit from intentional weight loss through a comprehensive management strategy; however, when we see that someone is losing weight without trying, it’s probably a poor prognostic sign, especially if they are already thin,” Baker added.

As new therapies and approaches to weight loss become available, these results will help promote their use in patients with arthritis, to help prevent disability over the long-term, the researcher said.

For the study, the team examined information on 23,323 patients with rheumatoid arthritis. (IANS)

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Obesity Alone Does not Increase Death Risk: Study

Earlier, a study, published in The Lancet Diabetes and Endocrinology journal, found that women with metabolically healthy obesity were at 39 per cent higher risk of cardiovascular disease

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The researchers looked at how many people within each group died as compared to those within the normal weight population with no metabolic risk factors.
The researchers looked at how many people within each group died as compared to those within the normal weight population with no metabolic risk factors. Pixabay

Patients who have metabolically healthy obesity but are free from other metabolic risk factors do not have an increased rate of mortality, a new study has found.

Metabolically healthy obesity is a debatable medical condition characterized by obesity which does not produce metabolic complications.

The study, published in the journal Clinical Obesity, showed that unlike dyslipidemia, hypertension and diabetes — each one of which is related to high mortality risk — obesity alone does not pose any threat to life.

“We are showing that individuals with metabolically healthy obesity are actually not at an elevated mortality rate,” said lead author Jennifer Kuk, Associate Professor at the York University in Canada.

“We found that a person of normal weight with no other metabolic risk factors is just as likely to die as the person with obesity and no other risk factors,” Kuk added.

Metabolically healthy obesity is a debatable medical condition characterized by obesity which does not produce metabolic complications.
Metabolically healthy obesity is a debatable medical condition characterized by obesity which does not produce metabolic complications. Pixabay

For the study, the research team followed 54,089 men and women from five cohort studies who were categorized as having obesity alone or clustered with a metabolic factor, or elevated glucose, blood pressure or lipids alone or clustered with obesity or another metabolic factor.

The researchers looked at how many people within each group died as compared to those within the normal weight population with no metabolic risk factors.

They found that one out of 20 individuals with obesity had no other metabolic abnormalities.

Also Read: Abdominal Obesity Linked to Lower Urinary Tract Symptoms

“This is in contrast with most of the literature and we think this is because most studies have defined metabolic healthy obesity as having up to one metabolic risk factor,” said Kuk.

“This is clearly problematic, as hypertension alone increases your mortality risk and past literature would have called these patients with obesity and hypertension, ‘healthy’. This is likely why most studies have reported that ‘healthy’ obesity is still related with higher mortality risk,” Kuk noted.

Earlier, a study, published in The Lancet Diabetes and Endocrinology journal, found that women with metabolically healthy obesity were at 39 per cent higher risk of cardiovascular disease. (IANS)