Tuesday July 23, 2019

Women can Boost their Working Memory with Hormone Therapy

Benefits of oestrogen therapy in women.

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oestrogen therapy can increase working memory under stress
oestrogen therapy can increase working memory under stress. wikimedia commons

New York, Nov 5: Undergoing a type of hormone replacement therapy — used for menopausal treatment — may help protect as well as improve working memory for some women as they age, according to a new study.

Hormone replacement therapy uses female hormones – oestrogen and progesterone – to treat common symptoms of menopause and ageing.

The findings showed that women taking oestrogen-only therapy had lower levels of the stress hormone cortisol and performed better on tests of “working memory” following exposure to stress compared to women taking a placebo.

“Our study suggests that oestrogen treatment after menopause protects the memory that is needed for short-term cognitive tasks from the effects of stress,” said lead author Alexandra Ycaza Herrera, a researcher at the University of Southern California – Davis.

To measure the effect of oestrogen therapy on working memory under stress, the team recruited 42 women with an average age of 66.

Half of the postmenopausal women had been on estradiol — a type of oestrogen therapy — for approximately five years, while the others had received a placebo.

The researchers, in the paper published in the Journal of Clinical Endocrinology and Metabolism, collected saliva to measure the women’s levels of cortisol, oestrogen, and progesterone.

They also ran a test of working memory called a “sentence span task”, in which the women were each given a series and then asked whether each sentence made sense. They also were asked to recall the last word of each one.

While women receiving oestrogen therapy had a smaller increase in cortisol and showed no decrease in working memory function, even after being exposed to stressful situation, those taking the placebo experienced a spike in cortisol levels as well as demonstrated a decrease in working memory function.

Previous studies have pointed to potential health risks — the Ahigher risk of breast cancer, heart disease, stroke and blood clots — of the treatment.

Thus, Herrera noted that “hormone replacement therapy may not be right for every woman, but women need to be able to have the conversation with their doctors”.(IANS)

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Study: Intake of Dietary Supplements May do More Harm than Benefit

The doctor suggested that people should include more green vegetables in their diet

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dietary supplements
According to the study published in the journal Annals of Internal Medicine, supplements combining calcium and vitamin D may be linked to a slightly increased stroke risk. Pixabay

Researchers have found that intake of some vitamins, minerals and other dietary supplements may not benefit the heart and, in some cases, may even prove to be injurious.

According to the study published in the journal Annals of Internal Medicine, supplements combining calcium and vitamin D may be linked to a slightly increased stroke risk. However, there was no evidence that calcium or vitamin D taken alone had any health risks or benefits.

“Our analysis carries a simple message that although there may be some evidence that a few interventions have an impact on death and cardiovascular health, the vast majority of multivitamins, minerals and different types of diets had no measurable effect on survival or cardiovascular disease risk reduction,” said study lead author Safi U. Khan, Assistant Professor at the West Virginia University.

For the study, the researchers used data from 277 randomised clinical trials that evaluated 16 vitamins or other supplements and eight diets for their association with mortality or heart conditions including coronary heart disease, stroke and heart attack.

dietary supplements
“People should focus on getting their nutrients from a heart-healthy diet, because the data increasingly show that the majority of healthy adults don’t need to take supplements,” Michos said. Wikimedia Commons

They included data gathered on 992,129 research participants worldwide. The analysis showed possible health benefits only from a low-salt diet, omega-3 fatty acid supplements and possibly folic acid supplements for some people.

“The panacea or magic bullet that people keep searching for in dietary supplements isn’t there,” said senior author of the study Erin Michos from Johns Hopkins University School of Medicine in the US.

“People should focus on getting their nutrients from a heart-healthy diet, because the data increasingly show that the majority of healthy adults don’t need to take supplements,” Michos said.

According to Abhishek Singh, Consultant Cardiologist at Columbia Asia Hospital in Ghaziabad, dietary supplements do not have a measurably positive impact on cardiac health.

dietary supplements
The doctor suggested that people should include more green vegetables in their diet. Pixabay

“It’s more important to follow a healthy dietary regimen and avoid foods that are bad for the heart. Trans fatty acids are harmful and have to be curtailed. Refined sugars and simple carbohydrates are to be kept at a minimum,” Singh told IANS.

The doctor suggested that people should include more green vegetables in their diet. They are rich in vitamin K and dietary nitrates, which help protect the arteries and reduce blood pressure, he said.

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“Studies like this raise concerns about harm from calcium and Vitamin D supplement use. As far as Vitamin D supplements (without calcium) are concerned, there has been no evidence on whether it has any impact on cardiovascular disease risk reduction,” Anupama Singh, Senior Consultant, Internal Medicine at Vimhans Nayati Super Specialty Hospital in Delhi, told IANS.

“The quality of the evidence base of these various nutritional supplements and dietary interventions still needs to be evaluated to ascertain the effectiveness of the study,” she added. (IANS)