Thursday August 16, 2018

Women can Boost their Working Memory with Hormone Therapy

Benefits of oestrogen therapy in women.

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oestrogen therapy can increase working memory under stress
oestrogen therapy can increase working memory under stress. wikimedia commons
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New York, Nov 5: Undergoing a type of hormone replacement therapy — used for menopausal treatment — may help protect as well as improve working memory for some women as they age, according to a new study.

Hormone replacement therapy uses female hormones – oestrogen and progesterone – to treat common symptoms of menopause and ageing.

The findings showed that women taking oestrogen-only therapy had lower levels of the stress hormone cortisol and performed better on tests of “working memory” following exposure to stress compared to women taking a placebo.

“Our study suggests that oestrogen treatment after menopause protects the memory that is needed for short-term cognitive tasks from the effects of stress,” said lead author Alexandra Ycaza Herrera, a researcher at the University of Southern California – Davis.

To measure the effect of oestrogen therapy on working memory under stress, the team recruited 42 women with an average age of 66.

Half of the postmenopausal women had been on estradiol — a type of oestrogen therapy — for approximately five years, while the others had received a placebo.

The researchers, in the paper published in the Journal of Clinical Endocrinology and Metabolism, collected saliva to measure the women’s levels of cortisol, oestrogen, and progesterone.

They also ran a test of working memory called a “sentence span task”, in which the women were each given a series and then asked whether each sentence made sense. They also were asked to recall the last word of each one.

While women receiving oestrogen therapy had a smaller increase in cortisol and showed no decrease in working memory function, even after being exposed to stressful situation, those taking the placebo experienced a spike in cortisol levels as well as demonstrated a decrease in working memory function.

Previous studies have pointed to potential health risks — the Ahigher risk of breast cancer, heart disease, stroke and blood clots — of the treatment.

Thus, Herrera noted that “hormone replacement therapy may not be right for every woman, but women need to be able to have the conversation with their doctors”.(IANS)
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Marital Spats May Deteriorate Your Health

Significant link between hostility and the biomarker LBP, which indicates the presence of bacteria in the blood. And there was a strong link between that biomarker and evidence of inflammation.

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How marital spats can affect your health. Pixabay

Couples, please take note. Fighting with your spouse may deteriorate your health, a new study has found.

The findings suggest that married people who fight are more likely to suffer from leaky guts — a problem that unleashes bacteria into the blood and can drive up disease-causing inflammation.

“We think that this everyday marital distress — at least for some people — is causing changes in the gut that lead to inflammation and, potentially, illness,” said lead author Janice Kiecolt-Glaser from the Ohio State University.

For the study published in the journal Psychoneuroendocrinology, the team recruited around 50 healthy married couples, surveyed them about their relationships and then encouraged them to discuss and try to resolve a conflict likely to provoke strong disagreement.

The researchers left the couples alone for these discussions, videotaped the 20-minute interactions and later watched how they fought.

Couples have tough time understanding soft negative emotions like sadness, loneliness of each other: Study.
Couples have tough time understanding soft negative emotions .

They categorised their verbal and non-verbal fighting behaviours, with special interest in hostility — things such as dramatic eye rolls or criticism of one’s partner.

The researchers also compared blood drawn pre-fight to blood drawn post-fight.

Men and women who demonstrated more hostile behaviours during the observed discussions had higher levels of one biomarker for leaky gut — LPS-binding protein — than their mellower peers, the researchers said.

Evidence of leaky gut was even greater in study participants who had particularly hostile interactions with their spouses and a history of depression or another mood disorder, they added.

Also Read: Reduce Loneliness and Boost Your Mental Health With Cycling

The study found a strong, significant link between hostility and the biomarker LBP, which indicates the presence of bacteria in the blood. And there was a strong link between that biomarker and evidence of inflammation.

Lifestyle changes that could contribute to decreased risk of gut-related inflammation include diets high in lean proteins, healthful fats, fruits, vegetables and whole grains. Probiotics might also be useful, Kiecolt-Glaser noted. (IANS)