Sunday May 27, 2018

Women can Boost their Working Memory with Hormone Therapy

Benefits of oestrogen therapy in women.

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oestrogen therapy can increase working memory under stress
oestrogen therapy can increase working memory under stress. wikimedia commons
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New York, Nov 5: Undergoing a type of hormone replacement therapy — used for menopausal treatment — may help protect as well as improve working memory for some women as they age, according to a new study.

Hormone replacement therapy uses female hormones – oestrogen and progesterone – to treat common symptoms of menopause and ageing.

The findings showed that women taking oestrogen-only therapy had lower levels of the stress hormone cortisol and performed better on tests of “working memory” following exposure to stress compared to women taking a placebo.

“Our study suggests that oestrogen treatment after menopause protects the memory that is needed for short-term cognitive tasks from the effects of stress,” said lead author Alexandra Ycaza Herrera, a researcher at the University of Southern California – Davis.

To measure the effect of oestrogen therapy on working memory under stress, the team recruited 42 women with an average age of 66.

Half of the postmenopausal women had been on estradiol — a type of oestrogen therapy — for approximately five years, while the others had received a placebo.

The researchers, in the paper published in the Journal of Clinical Endocrinology and Metabolism, collected saliva to measure the women’s levels of cortisol, oestrogen, and progesterone.

They also ran a test of working memory called a “sentence span task”, in which the women were each given a series and then asked whether each sentence made sense. They also were asked to recall the last word of each one.

While women receiving oestrogen therapy had a smaller increase in cortisol and showed no decrease in working memory function, even after being exposed to stressful situation, those taking the placebo experienced a spike in cortisol levels as well as demonstrated a decrease in working memory function.

Previous studies have pointed to potential health risks — the Ahigher risk of breast cancer, heart disease, stroke and blood clots — of the treatment.

Thus, Herrera noted that “hormone replacement therapy may not be right for every woman, but women need to be able to have the conversation with their doctors”.(IANS)
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World Health Organization Preparing For Some Significant Modifications

The World Health Assembly, the decision-making body of the WHO, passed a number of resolutions aimed at improving global health.

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WHO chief Tedros Adhanom Ghebreyesus paid homage to his predecessor, Margaret Chan, saying the reforms begun under her leadership to make the World Health Organization more responsive and better able to tackle emergencies were now paying off.
Tedros Adhanom Ghebreyesus, director general of the World Health Organization. VOA

The World Health Organization’s annual conference ended on a high note Saturday, with the organization’s director general praising delegates for giving him a strong mandate to implement an ambitious program of reforms and initiatives that will improve global health.

WHO chief Tedros Adhanom Ghebreyesus paid homage to his predecessor, Margaret Chan, saying the reforms begun under her leadership to make the World Health Organization more responsive and better able to tackle emergencies were now paying off.

“The current Ebola outbreak in the Democratic Republic of the Congo has demonstrated exactly that. … Let me assure you that I am personally committed to ensuring that we do everything we can to stop this outbreak as soon as possible,” Tedros said. “And the commitment of the government, of course, and the leadership is at the center, which we really admire.”

WHO chief Tedros Adhanom Ghebreyesus paid homage to his predecessor, Margaret Chan, saying the reforms begun under her leadership to make the World Health Organization more responsive and better able to tackle emergencies were now paying off.
The World Health Assembly, the decision-making body of the WHO, passed a number of resolutions aimed at improving global health. Wikimedia Common

The World Health Assembly, the decision-making body of the WHO, passed a number of resolutions aimed at improving global health. Some deal with diseases that have plagued humanity for centuries, while others are newly emerging.

But all these decisions, Tedros said, involve commitments to make the world a healthier, safer place. For example, he noted the assembly had approved a road map to reduce deaths from cholera by 90 percent by 2030.

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“You endorsed our five-year strategic plan on polio transition, to strengthen country health systems that could be affected by the scaling down of the Global Polio Eradication Initiative,” he said. “You passed resolutions on tuberculosis and noncommunicable diseases. … And you have agreed to increase the development and use of digital technologies to improve health and keep the world safe.”

Tedros urged the delegates to go back to their countries with renewed determination to work every day for the health of their people. How well they succeed in this endeavor, he said, will be measured by the outcomes, by whether they result in real change on the ground. (VOA)