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Anti-depressants may increase the risk of developing bone fractures, says a new study

New York, November 6, 2017 : Consuming opioids and anti-depressants may increase the risk of developing bone fractures among people who are already suffering from rheumatoid arthritis, says a new study.

Rheumatoid arthritis is a chronic disease that causes pain, stiffness, swelling, and limitation in the motion and function of multiple joints and organs of the body.


Chronic inflammation and pain in arthritis patients further leads to several diseases like cardiovascular, mental and gastrointestinal disorders. People take multiple medications in such cases that sometimes influences the risk of osteoporotic fractures or a disease caused due to reduced bone density, the researchers noted.

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“Even at younger ages, rheumatoid arthritis is associated with a two-fold increased risk of osteoporosis and fractures due to chronic inflammation and glucocorticoid use. More importantly, osteoporotic fractures significantly contribute to the disability, health-related costs and mortality with substantially higher complication in rheumatoid arthritis patients,” said Gulsen Ozen, researcher at the University of Nebraska Medical Centre.

The researchers evaluated 11,049 rheumatoid arthritis patients, aged 40 and above, with no signs of osteoporotic fractures prior to the tests. After a median follow-up time of 5.7 years, the study found 863 patients affected with osteoporotic fractures.

The patients who developed fractures were significantly older and had higher disease risk and bone fracture risk at the baseline than those patients who did not experience fractures.

The results presented at the ACR/ARHP annual meeting 2017 in San Diego mentioned that the osteoporotic fracture risk increased within 30 days when the patients were given opioids. The associated medications also led to falls in certain cases.

“Knowing the risks associated with the use of these medications can guide rheumatologists and other physicians in choosing the most appropriate management strategies in patients, particularly the ones who have a high fracture or fall risk,” Ozen added. (IANS)


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At a Department of Justice news conference Tuesday in Washington, officials said they arrested 150 people for allegedly selling illicit drugs, including fake prescription opioids and cocaine, over the so-called darknet. Those charged are alleged to have carried out tens of thousands of illegal sales using a part of the internet that is accessible only by using specialized anonymity tools.

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Currently, when users set up WhatsApp Pay in India, the service only verifies the phone number linked to your bank account to enable UPI-based transactions

Facebook-owned WhatsApp may soon ask users to verify their identity to make payments on the platform. According to XDA Developers, new strings spotted in the latest WhatsApp beta release suggest that the messenger will require users to upload verification documents to continue using payments on WhatsApp. Currently, when users set up WhatsApp Pay in India, the service only verifies the phone number linked to your bank account to enable UPI-based transactions. In Brazil, the messenger uses Facebook Pay to validate users' credit or debit cards to facilitate payments.

At the moment, the service doesn't require users to submit any identity verification documents to make payments. However, that might change soon, the report said. WhatsApp v2.21.22.6 beta includes a few new strings which suggest that users might have to submit identity verification documents to continue using payments.

The identity verification might be limited to those who use WhatsApp Pay to receive payments for their businesses. UPI-based apps, like Google Pay, PhonePe and even WhatsApp Pay don't require users to submit any documents to transfer or receive money. However, wallet apps like PayTM do ask for KYC verification as per RBI guidelines.

WhatsApp is yet to make an official announcement regarding this change. Since the new strings have just made their way to the beta version, it might be a while before the company reveals any details, the report said. (IANS/ MBI)


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