Sunday June 16, 2019

Oral Antibiotics Possess Threat of Kidney Stones

For broad-spectrum penicillins, the increased risk was 27 per cent higher, the researchers added.

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Antibiotics can develop kidney stones, Pixabay

Children and adults treated with oral antibiotics may have a higher risk of developing kidney stones, according to a new study.

The findings, published in Journal of the American Society of Nephrology, suggested that the strongest risks appeared at younger ages and among patients most recently exposed to antibiotics.

“The overall prevalence of kidney stones has risen by 70 per cent over the past 30 years, with particularly sharp increases among adolescents and young women,” said lead author Gregory E. Tasian from the Children’s Hospital of Philadelphia (CHOP).

According to the researchers, kidney stones were previously rare in children.

“The reasons for the increase are unknown, but our findings suggest that oral antibiotics play a role, especially given that children are prescribed antibiotics at higher rates than adults,” said co-author Michelle Denburg from CHOP.

Children and adults treated with oral antibiotics may have a higher risk of developing kidney stones, according to a new study.
Antibiotics, Pixabay

For the study, the team analysed prior antibiotic exposure for nearly 26,000 patients with kidney stones, compared to nearly 260,000 control subjects.

They found that five classes of oral antibiotics — oral sulfas, cephalosporins, fluoroquinolones, nitrofurantoin, and broad-spectrum penicillins — were associated with a diagnosis of kidney stone disease.

After adjustments for age, sex, race, urinary tract infection, other medications and medical conditions, patients who received sulfa drugs were more than twice as likely as those not exposed to antibiotics to have kidney stones, the researchers said.

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For broad-spectrum penicillins, the increased risk was 27 per cent higher, the researchers added.

They also mentioned that the risk of kidney stones decreased over time but remained elevated several years after antibiotic use.

“Our findings suggest that antibiotic prescription practices represent a modifiable risk factor, a change in prescribing patterns might decrease the current epidemic of kidney stones in children,” Tasian noted. (IANS)

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High Consumption of Junk Food May Spike up Allergies in Children

The study revealed a significant correlation between AGEs and junk food consumption, said Roberto Berni Canani, Associate Professor at the University of Naples Federico II in Italy

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Junk Food. Wikimedia Commons

Researchers have found that high consumption of junk food such as microwaved foods and barbequed meats may be responsible for food allergies in children.

The study, presented at the 52nd Annual Meeting of the European Society for Paediatric Gastroenterology Hepatology and Nutrition, shows that high levels of advanced glycation end-products (AGEs) are associated with food allergies in kids.

AGEs are present in high levels in junk foods such as sugars, processed foods, microwaved foods and roasted or barbequed meats. They are known to play a role in the development and progression of different oxidative-based diseases including diabetes, atherosclerosis and neurological disorders, said the researchers.

Cholesterol -- a molecule normally linked with cardiovascular diseases -- may also play an important role in the onset and progression of Alzheimer's disease, researchers have found.
Junk Food is highly rich in Cholesterol. Pixabay

For the study, the research team observed 61 children aged between 6 and 12 years. They were identified in three categories – those with food allergies, those with respiratory allergies and healthy controls.

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The study revealed a significant correlation between AGEs and junk food consumption, said Roberto Berni Canani, Associate Professor at the University of Naples Federico II in Italy. (IANS)