Tuesday January 22, 2019

Oral Antibiotics Possess Threat of Kidney Stones

For broad-spectrum penicillins, the increased risk was 27 per cent higher, the researchers added.

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Antibiotics can develop kidney stones, Pixabay

Children and adults treated with oral antibiotics may have a higher risk of developing kidney stones, according to a new study.

The findings, published in Journal of the American Society of Nephrology, suggested that the strongest risks appeared at younger ages and among patients most recently exposed to antibiotics.

“The overall prevalence of kidney stones has risen by 70 per cent over the past 30 years, with particularly sharp increases among adolescents and young women,” said lead author Gregory E. Tasian from the Children’s Hospital of Philadelphia (CHOP).

According to the researchers, kidney stones were previously rare in children.

“The reasons for the increase are unknown, but our findings suggest that oral antibiotics play a role, especially given that children are prescribed antibiotics at higher rates than adults,” said co-author Michelle Denburg from CHOP.

Children and adults treated with oral antibiotics may have a higher risk of developing kidney stones, according to a new study.
Antibiotics, Pixabay

For the study, the team analysed prior antibiotic exposure for nearly 26,000 patients with kidney stones, compared to nearly 260,000 control subjects.

They found that five classes of oral antibiotics — oral sulfas, cephalosporins, fluoroquinolones, nitrofurantoin, and broad-spectrum penicillins — were associated with a diagnosis of kidney stone disease.

After adjustments for age, sex, race, urinary tract infection, other medications and medical conditions, patients who received sulfa drugs were more than twice as likely as those not exposed to antibiotics to have kidney stones, the researchers said.

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For broad-spectrum penicillins, the increased risk was 27 per cent higher, the researchers added.

They also mentioned that the risk of kidney stones decreased over time but remained elevated several years after antibiotic use.

“Our findings suggest that antibiotic prescription practices represent a modifiable risk factor, a change in prescribing patterns might decrease the current epidemic of kidney stones in children,” Tasian noted. (IANS)

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Vaccination Not Forced on Children: Delhi Health Authorities

The prime target, according to the Ministry, is immunising children in the pre-schools, school children from both government and private institutions and those out of school

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Vaccination
Vaccination not forced on children: Delhi health authorities. Flickr

The measles and rubella (MR) vaccination programme, which was deferred following an intervention by the Delhi High Court, does not override the consent of students, said state’s health authorities for the campaign.

“It is totally wrong to say that vaccination was administered without consent. Though there has never been the process of seeking permission for any vaccination from guardians, people are free to refuse vaccination as we don’t force anyone,” Dr Suresh Seth, Delhi programme chief for immunisation told IANS on Wednesday.

The Delhi High Court on Tuesday deferred implementation of the “Measles and Rubella (MR) Vaccine Immunisation Campaign”, saying that vaccination cannot be administered “forcibly” and without the consent of parents.

The court’s order came while hearing pleas by parents of some minor students at city’s schools alleging that the MR campaign is a “violation of the fundamental rights” of the students as their consent had not been taken.

China, Vaccines
A child receives a vaccination shot at a hospital in Rongan in China’s southern Guangxi region on July 23, 2018. VOA

“We will comply with court’s orders. Our preparations are same and will start the very next day the high court gives clearance for the campaign,” Dr Seth said.

The Delhi Health Department will also share inputs with the Health and Welfare Family Ministry, which has been asked by the high court to respond by January 21.

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The measles and rubella vaccination campaign was scheduled to begin in the national capital from January 15, aiming at immunising nearly 55 lakh children in the age group of 9 months up to 15 years across 11 districts of Delhi.

The prime target, according to the Ministry, is immunising children in the pre-schools, school children from both government and private institutions and those out of school. (IANS)