Saturday September 21, 2019

New Study Reveals, Duration of Over-Feeding Are Directed at Increasing Glucose Disposal

"early adaptations in response to carbohydrate over-feeding are directed at increasing glucose disposal in order to maintain whole-body insulin sensitivity"

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Lifestyle factors such as overindulging in high-calorie foods play a large role in the development of these two serious health conditions. Pixabay

Overeating has been found to impair blood sugar (glucose) control and insulin levels but a new study suggests that the duration of a bout of overeating can affect how the body adapts to glucose and insulin processing when calorie intake increases.

Obesity and type 2 diabetes have increased significantly worldwide within the past 30 years.

Lifestyle factors such as overindulging in high-calorie foods play a large role in the development of these two serious health conditions.

diabetes
“Long-term overindulgence in fatty foods, instead of more nutritionally balanced foods, may be an important factor that causes rapid changes in blood sugar control,” the study added. Pixabay

For the study, researchers from Deakin University in Australia studied a small group of healthy and lean men with an average age of 22.

Volunteers participated in a short-term trial consisting of five days — indicative of humans overeating during festivals and holidays — and a long-term model of chronic overeating lasting 28 days.

The “overfeeding” portion of the diet included high-calorie snacks such as chocolate, meal replacement drinks and potato chips to add approximately 1,000 more calories to the men’s normal food consumption each day.

diabetes
Obesity and type 2 diabetes have increased significantly worldwide within the past 30 years. Pixabay

Published in the American Journal of Physiology-Endocrinology and Metabolism, the study suggests that “early adaptations in response to carbohydrate over-feeding are directed at increasing glucose disposal in order to maintain whole-body insulin sensitivity”.

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“Long-term overindulgence in fatty foods, instead of more nutritionally balanced foods, may be an important factor that causes rapid changes in blood sugar control,” the study added. (IANS)

Next Story

Low-Cost Text Messaging Programme Improves Blood Sugar Control in Patients with Diabetes

Capitalising on the exponential growth in mobile phone usage over the past decade, a simple text messaging programme could increase the reach

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Diabetes, Messaging, Blood Sugar
The effect in this study was not only statistically significant but also has the potential to be clinically relevant by reducing risk of diabetic complications and death. Pixabay

Researchers have found that a low-cost text messaging programme improves blood sugar control in patients with diabetes and coronary heart disease.

“The effect in this study was not only statistically significant but also has the potential to be clinically relevant by reducing risk of diabetic complications and death,” said study researcher Xiqian Huo from Fuwai Hospital in China.

“Capitalising on the exponential growth in mobile phone usage over the past decade, a simple text messaging programme could increase the reach of diabetes self-management support,” she added.

It may provide a means to better address the burgeoning healthcare demand-capacity imbalance.

Diabetes, Messaging, Blood Sugar
Researchers have found that a low-cost text messaging programme improves blood sugar control in patients with diabetes and coronary heart disease. Pixabay

For the study presented at the ESC Congress 2019 in France, the researchers enrolled 502 patients from 34 clinics in China and the patients were randomly assigned to the text messaging intervention or a control group for six months.

The intervention group received six messages per week, at random times of the day, from an automated system set up by the researchers.

The messages were designed to provide information and motivation and help patients set goals and manage stress.

The control group received two thank you text messages per month.

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At six months, blood glycated haemoglobin (HbA1c) was significantly lower in the intervention group compared to the control group (6.7 per cent versus 7.2 per cent).

On an average, HbA1c fell by 0.2 per cent in the intervention group and rose by 0.1 per cent in the control group – a difference of 0.3 per cent between groups.

The change in fasting blood glucose was larger in the intervention, compared to control, group (-0.5 versus 0.1 mmol/L, respectively).

The intervention was acceptable to participants, 97 per cent found the text messages useful, readable and an appropriate method of contact. (IANS)