Monday July 23, 2018

Overweight in Middle Age Linked to Low Breast Cancer Risk

At ages 25 to 34, each five-unit increase in BMI was linked to 15 per cent lower risk

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Having your last meal before 9 pm or at least two hours before going to bed could lower the risk of breast and prostate cancer
Having your last meal before 9 pm or at least two hours before going to bed could lower the risk of breast and prostate cancer. Pixabay
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While obesity has been shown to increase breast cancer risk in elderly, for younger women the opposite seems to be true. For pre-menopausal women, a higher body fat was linked to lower breast cancer risk, according to researchers.

The study, published in the journal JAMA Oncology, showed that there was 23 per cent lower breast cancer risk linked to each five-unit increase in body mass index (BMI) between the ages of 18 and 24.

At ages 25 to 34, each five-unit increase in BMI was linked to 15 per cent lower risk.

There was a 13 per cent lower risk for BMI at ages 35 to 44, and a 12 per cent lower risk for BMI at ages 45 to 54 years.

“We saw a trend where, as BMI went up, cancer risk went down. There was no threshold at which having a higher BMI was linked to lower cancer risk,” said Hazel B. Nichols, assistant professor at the University of North Carolina.

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Representational image. Pixabay

The trend could be attributed to multiple factors such as differences in hormones, including estrogen — primary female sex hormone — growth factors, or breast density, Nichols said.

Estrogen has known to be a key driver of breast cancer. But, the small amount of estrogen produced by fat tissue before menopause may help tell the ovaries that they can produce less estrogen and also regulate other hormones or growth factors, Nichols said, adding that after menopause, women with higher adipose tissue have higher estrogen levels and usually a higher breast cancer risk.

“In young women, estrogen is one factor that contributes, but it’s not the whole story,” she noted.

Also Read: Cancer: Salient Features of The Killer Disease

For the study, the team pooled data from 19 different studies to investigate breast cancer risk for a group of 758,592 women who were younger than 55 years.

However, “this study is not a reason to try to gain weight to prevent breast cancer. Heavier women have a lower overall risk of breast cancer before menopause, but there are a lot of other benefits to managing a healthy weight that should be considered,” Nichols noted. (IANS)

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Eating Dinner Early May Lower Risk of Breast, Prostate Cancer

The research suggests that long-term late night snacking may have the similar effect to night-shift work and circadian disruption

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The researchers found that cancer patients were more likely to have dinner late at night. Pixabay

Having your last meal before 9 pm or at least two hours before going to bed could lower the risk of breast and prostate cancer, suggests a new study.

Compared to those who have supper after 10 pm or those who go to bed right after meal, people who take their evening meal before 9 pm or wait at least two hours before going to sleep have approximately 20 per cent lower risk of those types of cancers, the findings showed.

“Our study concludes that adherence to diurnal eating patterns is associated with a lower risk of cancer,” said lead author Manolis Kogevinas from the Barcelona Institute for Global Health (ISGlobal) in Spain.

“The findings highlight the importance of assessing circadian rhythms in studies on diet and cancer,” Kogevinas added.

For the study, published in International Journal of Cancer, the team analysed data from 621 cases of prostate cancer and 1,205 cases of breast cancer, as well as 872 male and 1,321 female controls.

Having your last meal before 9 pm or at least two hours before going to bed could lower the risk of breast and prostate cancer
Having your last meal before 9 pm or at least two hours before going to bed could lower the risk of breast and prostate cancer. Pixabay

The participants, were interviewed about their meal timing, sleep habits and chronotype — an individual attribute correlating with preference for morning or evening activity.

The participants also completed a questionnaire on their eating habits and adherence to cancer prevention recommendations.

The researchers found that cancer patients were more likely to have dinner late at night.

Also Read: Meditation Improves Mood, Sleep in Teenagers with Cancer

Breast and prostate cancers are also among those most strongly associated with night-shift work, circadian disruption and alteration of biological rhythms.

The research suggests that long-term late night snacking may have the similar effect to night-shift work and circadian disruption.

“If the findings are confirmed, they will have implications for cancer prevention recommendations, which currently do not take meal timing into account,” Kogevinas noted. (IANS)