Sunday April 21, 2019

Why you should avoid Paracetamol during pregnancy

The study shows, paracetamol could affect your daughters fertility

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Consumption of Paracetamol during pregnancy may affect the fertility of your daughter. Pixabay
Consumption of Paracetamol during pregnancy may affect the fertility of your daughter. Pixabay

Women who consume paracetamol during pregnancy, widely used to reduce a high fever or relieve pain, may increase the risk of damaging the fertility of their daughters, warns a new study.

“This study identifies a potential risk from taking parace0tamol or ibuprofen, although we don’t know exactly what effect it would have on human health nor what dose would be needed to harm fertility,” said Richard Sharpe, professor at the varsity.

Read more: Open defecation affects pregnancy, reveals study

Findings

Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells. Pixabay
Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells. Pixabay
  • Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells.
  • If this effect occurs in the womb, it could mean baby girls exposed to the common drug end up being born with fewer eggs.
  • This would give them fewer years in which they could become pregnant and lead to an early menopause.
  • It may be because both paracetamol and ibuprofen interferes with a hormone called prostaglandin E2, which appears to play a vital part in the development of the foetal reproductive system.

Also read: Pregnancy seems Safe for Breast Cancer Survivors: Study

The findings prompts fresh warnings for pregnant women to only take paracetamol when necessary and warrants further research. Pixabay
The findings prompts fresh warnings for pregnant women to only take paracetamol when necessary and warrants further research. Pixabay

Methodology

  • The team tested the effect of paracetamol and ibuprofen on human foetal testes and ovaries over a week. Researchers counted germ cells that turn into sperm and eggs.
  • In the ovary, the number of egg cells fell by up to 40 per cent, while in testes the number of germ cells was reduced by more than a fifth.

While unborn boys could also be affected by the drug. But unlike women, whose egg supply is limited, they keep producing sperm throughout their lives, meaning the danger to their fertility is not as serious, the researchers said.

Next Story

Avoid Smoking During Pregnancy To Prevent Premature Births

The negative health impacts of cigarette smoking during pregnancy, including low birth weight, delayed intrauterine development, pre-term birth, infant mortality, and long-term developmental delays, are well known. 

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The researcher plans to look at quit rates and smoking intensity and their impact on the risk of infant mortality. Pixabay

Expecting mothers, take note. As smoking during pregnancy is linked with negative health outcomes, a team of researchers has found that smoking cessation during pregnancy may reduce the risk of pre-term birth.

The findings, published in the JAMA Network Open journal, showed that the probability of pre-term birth decreased with earlier smoking cessation in pregnancy — up to a 20 per cent relative decrease if cessation occurred at the beginning of pregnancy.

baby
If we determine quitting, and quitting early, reduces the risk of infant mortality, then that may speak to mothers even more saliently about the importance of smoking cessation. Pixabay

“Of concern, though, given the substantial benefits of smoking cessation during pregnancy is that the proportion of pre-pregnancy smokers who quit smoking during pregnancy has remained essentially stagnant since 2011,” said lead author Samir Soneji from The Dartmouth Institute for Health Policy and Clinical Practice in the US.

For the study, the researchers conducted a cross-sectional study of more than 25 million pregnant women who gave birth to live neonates during a six-year period — measuring their smoking frequency three months prior to pregnancy and for each trimester during pregnancy.

The negative health impacts of cigarette smoking during pregnancy, including low birth weight, delayed intrauterine development, pre-term birth, infant mortality, and long-term developmental delays, are well known.

But the good news is that the proportion of women who start their pregnancy as smokers has been declining in recent years, the researchers said.

smoking

The findings, published in the JAMA Network Open journal, showed that the probability of pre-term birth decreased with earlier smoking cessation in pregnancy — up to a 20 per cent relative decrease if cessation occurred at the beginning of pregnancy. Pixabay

However, the study also found that only about 25 per cent of women who smoked prior to pregnancy were able to quit throughout their pregnancy, and approximately 50 per cent of women who smoked during their pregnancy did so with high frequency (more than 10 cigarettes per day).

The researcher plans to look at quit rates and smoking intensity and their impact on the risk of infant mortality.

Also Read: How Netflix Binge-Watching Can Lead You The “Mean World Syndrome”

“Thankfully most premature babies end up doing well,” he said.

“But premature birth is strongly linked to infant mortality. If we determine quitting, and quitting early, reduces the risk of infant mortality, then that may speak to mothers even more saliently about the importance of smoking cessation,” he added. (IANS)