Monday January 21, 2019

Why you should avoid Paracetamol during pregnancy

The study shows, paracetamol could affect your daughters fertility

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Consumption of Paracetamol during pregnancy may affect the fertility of your daughter. Pixabay
Consumption of Paracetamol during pregnancy may affect the fertility of your daughter. Pixabay

Women who consume paracetamol during pregnancy, widely used to reduce a high fever or relieve pain, may increase the risk of damaging the fertility of their daughters, warns a new study.

“This study identifies a potential risk from taking parace0tamol or ibuprofen, although we don’t know exactly what effect it would have on human health nor what dose would be needed to harm fertility,” said Richard Sharpe, professor at the varsity.

Read more: Open defecation affects pregnancy, reveals study

Findings

Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells. Pixabay
Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells. Pixabay
  • Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells.
  • If this effect occurs in the womb, it could mean baby girls exposed to the common drug end up being born with fewer eggs.
  • This would give them fewer years in which they could become pregnant and lead to an early menopause.
  • It may be because both paracetamol and ibuprofen interferes with a hormone called prostaglandin E2, which appears to play a vital part in the development of the foetal reproductive system.

Also read: Pregnancy seems Safe for Breast Cancer Survivors: Study

The findings prompts fresh warnings for pregnant women to only take paracetamol when necessary and warrants further research. Pixabay
The findings prompts fresh warnings for pregnant women to only take paracetamol when necessary and warrants further research. Pixabay

Methodology

  • The team tested the effect of paracetamol and ibuprofen on human foetal testes and ovaries over a week. Researchers counted germ cells that turn into sperm and eggs.
  • In the ovary, the number of egg cells fell by up to 40 per cent, while in testes the number of germ cells was reduced by more than a fifth.

While unborn boys could also be affected by the drug. But unlike women, whose egg supply is limited, they keep producing sperm throughout their lives, meaning the danger to their fertility is not as serious, the researchers said.

Next Story

Sleeping for Long Hours During Pregnancy Linked to Stillbirths

Progress in reducing stillbirth deaths has been slow but stillbirth is an urgent global health issue that should be at the centre of more research programmes, the researchers noted

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Pregnancy, air pollution
Sleeping for long hours during pregnancy linked to stillbirths. Pixabay

Sleeping more than nine hours per night during pregnancy may be associated with late stillbirth, suggests a new study.

This is because blood pressure reaches its lowest point during sleep which has been linked with foetal growth problems, preterm birth, and stillbirth.

The study, led by a team from the University of Michigan, explored how maternal sleep habits, including lengthy periods of sleep without waking more than once in the night, may be associated with foetal health independent of other risk factors.

Moreover, pregnant women often report waking up and getting up in the middle of the night.

Very disruptive sleep has also been associated with poor pregnancy outcomes, including growth restriction and preterm growth.

Protein responsible for postpartum depression in pregnancy found
Representational image. IANS

“Our findings add to research indicating that maternal sleep plays a role in foetal well being. Studies aiming to reduce stillbirths should consider maternal sleep as this is a potentially modifiable risk factor,” said lead author Louise O’Brien, researcher at the varsity.

“Understanding the role of maternal sleep may help us identify interventions that would put us in a better position to advise women,” O’Brien added.

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For the study, reported in the journal Birth, the team involved 153 women who had experienced a late stillbirth (on or after 28 weeks of pregnancy) within the previous month and 480 women with an ongoing third-trimester pregnancy or who had recently delivered a live born baby during the same period.

Progress in reducing stillbirth deaths has been slow but stillbirth is an urgent global health issue that should be at the centre of more research programmes, the researchers noted. (IANS)