Wednesday September 19, 2018

Why you should avoid Paracetamol during pregnancy

The study shows, paracetamol could affect your daughters fertility

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Consumption of Paracetamol during pregnancy may affect the fertility of your daughter. Pixabay
Consumption of Paracetamol during pregnancy may affect the fertility of your daughter. Pixabay
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Women who consume paracetamol during pregnancy, widely used to reduce a high fever or relieve pain, may increase the risk of damaging the fertility of their daughters, warns a new study.

“This study identifies a potential risk from taking parace0tamol or ibuprofen, although we don’t know exactly what effect it would have on human health nor what dose would be needed to harm fertility,” said Richard Sharpe, professor at the varsity.

Read more: Open defecation affects pregnancy, reveals study

Findings

Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells. Pixabay
Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells. Pixabay
  • Human ovaries exposed to paracetamol for a week in laboratories lost up to 40 per cent of their egg cells.
  • If this effect occurs in the womb, it could mean baby girls exposed to the common drug end up being born with fewer eggs.
  • This would give them fewer years in which they could become pregnant and lead to an early menopause.
  • It may be because both paracetamol and ibuprofen interferes with a hormone called prostaglandin E2, which appears to play a vital part in the development of the foetal reproductive system.

Also read: Pregnancy seems Safe for Breast Cancer Survivors: Study

The findings prompts fresh warnings for pregnant women to only take paracetamol when necessary and warrants further research. Pixabay
The findings prompts fresh warnings for pregnant women to only take paracetamol when necessary and warrants further research. Pixabay

Methodology

  • The team tested the effect of paracetamol and ibuprofen on human foetal testes and ovaries over a week. Researchers counted germ cells that turn into sperm and eggs.
  • In the ovary, the number of egg cells fell by up to 40 per cent, while in testes the number of germ cells was reduced by more than a fifth.

While unborn boys could also be affected by the drug. But unlike women, whose egg supply is limited, they keep producing sperm throughout their lives, meaning the danger to their fertility is not as serious, the researchers said.

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High Sugar Levels In Mothers Can Risk Obesity In Child: Study

Lowering a mother's blood sugar during her pregnancy reduces the birth weight of the child.

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Pregnancy
Maternal high blood sugar linked to obesity risk in kids. Pixabay

Babies born to woman with higher blood sugar levels during pregnancy could be at significantly greater long-term risk of obesity – even more than a decade later, a study has found.

The higher the woman’s blood sugar, the greater the risk of her child being obese.

The researchers suspect that epigenetic changes are likely to be influencing these long-term outcomes and those changes begin quite early in pregnancy.

Pregnancy
Maternal high blood sugar linked to obesity risk in kids Pixabay

“The mother’s blood sugar level during pregnancy is an independent contributor to the child’s weight and risk of being obese later in childhood,” said Boyd Metzger, professor at the Northwestern University Feinberg School of Medicine.

In addition, mothers with higher-than-normal blood sugar during pregnancy — even if not at the level of gestational diabetes — also were significantly more likely to have developed Type-2 diabetes a decade after pregnancy than their counterparts without high blood sugar, the researchers said, in the paper published in the journal JAMA.

Lowering a mother’s blood sugar during her pregnancy reduces the birth weight of the child, as well as the risk of pre-eclampsia — potentially life-threatening condition in which the mother has high blood pressure that affects her and the baby.

Pregnancy
The higher the woman’s blood sugar, the greater the risk of her child being obese. Pixabay

If not regulated on time, these can potentially increase the number of women and children at risk of acquiring lifelong chronic medical conditions.

“The results are important because they demonstrate that even women with mild hyperglycemia during pregnancy and their offspring are at risk of harmful maternal and child health outcomes,” said coauthor Wendy Brickman, associate professor at Feinberg.

“Research is needed to identify interventions that will improve the health outcomes of these women and children,” Brickman said.

Also Read: Weight Loss Tip- Chinese Medicine Ingredient May Help Reduce Obesity

The study evaluated children 10 to 14 years after birth in 10 clinical centers in seven countries: the US, Canada, Israel, the UK, Hong Kong, Thailand and Barbados.

The study included 4,697 mothers and 4,832 children. (IANS)