Monday June 25, 2018

Partially Effective HIV Vaccine can Help to prevent millions of infections Each Year: Researchers

According to the model by the scientists of Oregon State University the world might expect to see about 49 million new cases of HIV in the next 20 years

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Pharmacist Mary Chindanyika labels a fridge containing a trail vaccine against HIV on the outskirts of Cape Town, South Africa, Wednesday, Nov. 30, 2016. A new trial for a vaccine against HIV was launched in South Africa Wednesday, amid hopes that even a modest protection rate could help stem the spread of the disease. The trial, known as HVTN 702, will enroll 5,400 sexually active men and women between ages 18 and 35 at 15 sites across South Africa. (AP Photo/Schalk van Zuydam), VOA
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Washington, March 22, 2017: When it comes to the deployment and use of an HIV vaccine, researchers say even a partially effective vaccine, although not perfect, still could prevent millions of infections each year.

There are no AIDS vaccines in use, but many are in the development pipeline or clinical trials. The problem is the vaccines are turning out to be less effective than hoped.

To get a handle on what the future might hold, scientists at Oregon State University developed a mathematical model of HIV progression, transmission and intervention, tailored to 127 countries around the world.

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According to the model, using current interventions, the world might expect to see about 49 million new cases of HIV in the next 20 years.

But the study concluded that 25 million of those infections might be prevented if ambitious targets for diagnosis, treatment and viral suppression set by the United Nations are met.

And that’s where an HIV vaccine comes in.

Jan Medlock, the study’s lead author, said adding a vaccine to the mix — even one that is only 50 percent effective — by 2020 could prevent another 6.3 million new infections, potentially reversing the HIV pandemic.

“Partial efficacy is still better than zero efficacy, and it really becomes (a matter) of thinking about the cost and trade-off,” she said. “Are you taking away money from treatment or some other health program to buy these vaccines? If not, then they’re probably worth doing, even at very low efficacy.”

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Medlock’s model — reported in the Proceedings of the National Academy of Sciences– input clinical data from a vaccine that’s now in large-scale trials in South Africa.

Until it was modified for the phase-three trial in the hopes of boosting its effectiveness, the vaccine candidate showed about a 60 percent efficacy in preventing infection for the first year. The effectiveness dropped to 31 percent 3½ years later.

Even without an improvement in current levels of HIV detection and treatment globally, a vaccine that’s only 50 percent effective has the potential to avert 17 million new cases during the next two decades, Medlock said.

Medlock added an even less effective vaccine could make a sizeable dent to slow the pandemic.

“Twenty percent efficacy at the global population scale is still going to prevent several million infections,” she said.

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Medlock said many countries will inevitably fall short of the U.N.’s ambitious goals to contain the HIV pandemic.

That’s why researchers believe the firepower of imperfect HIV vaccines should be brought to bear in the fight against the AIDS virus. (VOA)

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FIFA World Cup 2018: Indian Cuisine becomes the most sought after in Moscow

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Indian cuisine in FIFA World cup
Indian dishes available in Moscow during FIFA World Cup 2018, representational image, wikimedia commons

June 17, 2018:

Restaurateurs Prodyut and Sumana Mukherjee have not only brought Indian cuisine to the ongoing FIFA World Cup 2018 here but also plan to dish out free dinner to countrymen if Argentina wins the trophy on July 15.

Based in Moscow for the last 27 years, Prodyut and Sumana run two Indian eateries, “Talk Of The Town” and “Fusion Plaza”.

You may like to read more on Indian cuisine: Indian ‘masala’, among other condiments spicing up global food palate.

Both restaurants serve popular Indian dishes like butter chicken, kebabs and a varied vegetarian spread.

During the ongoing FIFA World Cup 2018, there will be 25 per cent discount for those who will possess a Fan ID (required to watch World Cup games).

There will also be gifts and contests on offers during matches in both the restaurants to celebrate the event.

The Mukherjees, hailing from Kolkata, are die-hard fans of Argentina. Despite Albiceleste drawing 1-1 with Iceland in their group opener with Lionel Messi failing to sparkle, they believe Jorge Sampaoli’s team can go the distance.

“I am an Argentina fan. I have booked tickets for a quarterfinal match, a semifinal and of course the final. If Argentina goes on to lift

During the World Cup, there will be 25 per cent discount for those who will possess a Fan ID (required to watch World Cup games).

There will also be gifts and contests on offers during matches in both the restaurants to celebrate the event.

FIFA World Cup 2018 Russia
FIFA World Cup 2018, Wikimedia Commons.

“We have been waiting for this World Cup. Indians come in large numbers during the World Cup and we wanted these eateries to be a melting point,” he added.

According to Cutting Edge Events, FIFA’s official sales agency in India for the 2018 World Cup, India is amongst the top 10 countries in terms of number of match tickets bought.

Read more about Indian cuisine abroad: Hindoostane Coffee House: London’s First Indian Restaurant.

Prodyut came to Moscow to study engineering and later started working for a pharmaceutical company here before trying his hand in business. Besides running the two restaurants with the help of his wife, he was into the distribution of pharmaceutical products.

“After Russia won the first match of the World Cup, the footfall has gone up considerably. The Indians are also flooding in after the 6-9 p.m. game. That is the time both my restaurants remain full,” Prodyut said.

There are also plans to rope in registered fan clubs of Latin American countries, who will throng the restaurants during matches and then follow it up with after-game parties till the wee hours.

“I did get in touch with some of the fan clubs I had prior idea about. They agreed to come over and celebrate the games at our joints. Those will be gala nights when both eateries will remain open all night for them to enjoy,” Prodyut said.

Watching the World Cup is a dream come true for the couple, Sumana said.

“We want to make the Indians who have come here to witness the spectacle and feel at home too. We always extend a helping hand and since we are from West Bengal, we make special dishes for those who come from Bengal,” she added. (IANS)