Wednesday September 19, 2018

Partially Effective HIV Vaccine can Help to prevent millions of infections Each Year: Researchers

According to the model by the scientists of Oregon State University the world might expect to see about 49 million new cases of HIV in the next 20 years

0
//
157
Pharmacist Mary Chindanyika labels a fridge containing a trail vaccine against HIV on the outskirts of Cape Town, South Africa, Wednesday, Nov. 30, 2016. A new trial for a vaccine against HIV was launched in South Africa Wednesday, amid hopes that even a modest protection rate could help stem the spread of the disease. The trial, known as HVTN 702, will enroll 5,400 sexually active men and women between ages 18 and 35 at 15 sites across South Africa. (AP Photo/Schalk van Zuydam), VOA
Republish
Reprint

Washington, March 22, 2017: When it comes to the deployment and use of an HIV vaccine, researchers say even a partially effective vaccine, although not perfect, still could prevent millions of infections each year.

There are no AIDS vaccines in use, but many are in the development pipeline or clinical trials. The problem is the vaccines are turning out to be less effective than hoped.

To get a handle on what the future might hold, scientists at Oregon State University developed a mathematical model of HIV progression, transmission and intervention, tailored to 127 countries around the world.

NewsGram brings to you current foreign news from all over the world.

According to the model, using current interventions, the world might expect to see about 49 million new cases of HIV in the next 20 years.

But the study concluded that 25 million of those infections might be prevented if ambitious targets for diagnosis, treatment and viral suppression set by the United Nations are met.

And that’s where an HIV vaccine comes in.

Jan Medlock, the study’s lead author, said adding a vaccine to the mix — even one that is only 50 percent effective — by 2020 could prevent another 6.3 million new infections, potentially reversing the HIV pandemic.

“Partial efficacy is still better than zero efficacy, and it really becomes (a matter) of thinking about the cost and trade-off,” she said. “Are you taking away money from treatment or some other health program to buy these vaccines? If not, then they’re probably worth doing, even at very low efficacy.”

NewsGram brings to you top news around the world today.

Medlock’s model — reported in the Proceedings of the National Academy of Sciences– input clinical data from a vaccine that’s now in large-scale trials in South Africa.

Until it was modified for the phase-three trial in the hopes of boosting its effectiveness, the vaccine candidate showed about a 60 percent efficacy in preventing infection for the first year. The effectiveness dropped to 31 percent 3½ years later.

Even without an improvement in current levels of HIV detection and treatment globally, a vaccine that’s only 50 percent effective has the potential to avert 17 million new cases during the next two decades, Medlock said.

Medlock added an even less effective vaccine could make a sizeable dent to slow the pandemic.

“Twenty percent efficacy at the global population scale is still going to prevent several million infections,” she said.

Check out NewsGram for latest international news updates.

Medlock said many countries will inevitably fall short of the U.N.’s ambitious goals to contain the HIV pandemic.

That’s why researchers believe the firepower of imperfect HIV vaccines should be brought to bear in the fight against the AIDS virus. (VOA)

Click here for reuse options!
Copyright 2017 NewsGram

Next Story

USA: Everything you want to know about Security Clearance; Find out here!

A security clearance allows a person access to classified national security information or restricted areas.

0
Former CIA Director John O. Brennan speaks at the Council on Foreign Relations in Washington, March 11, 2014. President Donald Trump revoked Brennan's security clearance Wednesday. VOA
Former CIA Director John O. Brennan speaks at the Council on Foreign Relations in Washington, March 11, 2014. President Donald Trump revoked Brennan's security clearance Wednesday. VOA

U.S. President Donald Trump on Wednesday revoked the security clearance of former CIA Director John Brennan. We take a look at what that means.

What is a security clearance?

A security clearance allows a person access to classified national security information or restricted areas after completion of a background check. The clearance by itself does not guarantee unlimited access. The agency seeking the clearance must determine what specific area of information the person needs to access.

What are the different levels of security clearance?

There are three levels: Confidential, secret and top secret. Security clearances don’t expire. But, top secret clearances are reinvestigated every five years, secret clearances every 10 years and confidential clearances every 15 years.

All federal agencies follow a list of 13 potential justifications for revoking or denying a clearance. VOA
All federal agencies follow a list of 13 potential justifications for revoking or denying a clearance. VOA

Who has security clearances?

According to a Government Accountability Office report released last year, about 4.2 million people had a security clearance as of 2015, they included military personnel, civil servants, and government contractors.

Why does one need a security clearance in retirement?

Retired senior intelligence officials and military officers need their security clearances in case they are called to consult on sensitive issues.

Also Read: Governments Across The World Request Apple for 30,000 Device Information

Can the president revoke a security clearance?

Apparently. But there is no precedent for a president revoking someone’s security clearance. A security clearance is usually revoked by the agency that sought it for an employee or contractor. All federal agencies follow a list of 13 potential justifications for revoking or denying a clearance, which can include criminal acts, lack of allegiance to the United States, behavior or situation that could compromise an individual and security violations. (VOA)