Thursday January 23, 2020

People Suffering from Insomnia Might have Increased Risk of Coronary Artery Disease, Heart Failure and Stroke

These observational studies were unable to determine whether insomnia is a cause, or if it is just associated with them

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Insomnia, Heart Disease, Heart Failure
According to researchers, previous observational studies have found an association between insomnia, which affects up to 30 per cent of the general population and an increased risk of developing heart disease and stroke. Pixabay

People suffering from insomnia might have an increased risk of coronary artery disease, heart failure and stroke, says a study.

According to researchers, previous observational studies have found an association between insomnia, which affects up to 30 per cent of the general population and an increased risk of developing heart disease and stroke.

“These observational studies were unable to determine whether insomnia is a cause, or if it is just associated with them,” said the study’s lead author Susanna Larsson, Associate Professor at the Karolinska Institute in Sweden.

In the study, the researchers applied Mendelian randomisation, a technique that uses genetic variants known to be connected with a potential risk factor, such as insomnia, to reduce bias in the results.

Insomnia, Heart Disease, Heart Failure
People suffering from insomnia might have an increased risk of coronary artery disease, heart failure and stroke, says a study. Pixabay

The 1.3 million participants with or without heart disease and stroke were drawn from four major public studies and groups, said the research published in the journal Circulation.

Researchers found genetic variants for insomnia were associated with significantly higher odds of coronary artery disease, heart failure and ischemic stroke – particularly large artery stroke.

“It is important to identify the underlying reason for insomnia and treat it.

“Sleep is a behaviour that can be changed by new habits and stress management,” Larsson said.

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A limitation to the study is that the results represent a genetic variant link to insomnia rather than insomnia itself. (IANS)

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Diabetes is an Independent Risk Factor For Heart Failure: Study

According to health expert in India, if poorly controlled, diabetes leads to cardiomyopathy resulting in progressive deterioration of pumping capacity of heart

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Diabetes
The study shows that diabetes is an independent risk factor for the development of heart failure in the community dwelling population. Pixabay

Heart problems are a common development for people with diabetes and now researchers have found that diabetes is an independent risk factor for the development of heart failure in the community dwelling population.

According to health expert in India, if poorly controlled, diabetes leads to cardiomyopathy resulting in progressive deterioration of pumping capacity of heart.

“Diabetes is also a major risk factor for atherosclerosis and this eventually leads to blockage of coronary arteries. This leads to heart attack or myocardial infarction,” Satish Koul, HOD and Director Internal Medicine, Narayana Superspeciality Hospital, Gurugram, told IANS. “Due to myocardial infarction, the heart muscle becomes weak and eventually heart fails as a pump leading to congestive heart failure,” Koul added.

According to the current study, published in the journal Mayo Clinic Proceedings, researchers evaluated the long-term impact of diabetes on the development of heart failure, both with preserved ejection fraction – a measurement of the percentage of blood leaving the heart with each contraction – and reduced ejection fraction. They also looked at mortality in a community population, controlling for hypertension, coronary artery disease and diastolic function.

From an initial group of 2,042 residents of Olmsted County in US, 116 study participants with diabetes were matched 1:2 for age, hypertension, sex, coronary artery disease and diastolic dysfunction to 232 participants without diabetes.

Over the 10-year follow-up period, 21 per cent of participants with diabetes developed heart failure, independent of other causes.

Diabetes
Heart problems are a common development for people with diabetes and now researchers have found that diabetes is an independent risk factor for the development of heart failure in the community dwelling population. Pixabay

In comparison, only 12 per cent of patients without diabetes developed heart failure. Cardiac death, heart attack and stroke were not statistically different in the study between the two groups.

The study shows that diabetes is an independent risk factor for the development of heart failure in the community dwelling population. Furthermore, the outcome data support the concept of a diabetic cardiomyopathy.

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This research extends previous findings and demonstrates that even without a known cardiac structural abnormality and with a normal ejection fraction, diabetic patients are still at increased risk of developing heart failure as compared to their nondiabetic counterparts. (IANS)