Get subscribed to our newsletter
Get interesting updates to your email inbox.
Scientists temporarily attached a pig's kidney to a human body and watched it begin to work, a small step in the decades-long quest to one day use animal organs for lifesaving transplants.
Pigs have been the most recent research focus to address the organ shortage, but among the hurdles: A sugar in pig cells, foreign to the human body, causes immediate organ rejection. The kidney for this experiment came from a gene-edited animal, engineered to eliminate that sugar and avoid an immune system attack.
Surgeons attached the pig kidney to a pair of large blood vessels outside the body of a deceased recipient so they could observe it for two days. The kidney did what it was supposed to do — filter waste and produce urine — and didn't trigger rejection.
"It had absolutely normal function," said Dr. Robert Montgomery, who led the surgical team last month at NYU Langone Health in New York. "It didn't have this immediate rejection that we have worried about."
This research is "a significant step," said Dr. Andrew Adams of the University of Minnesota Medical School, who was not part of the work. It will reassure patients, researchers and regulators "that we're moving in the right direction."
The dream of animal-to-human transplants, or xenotransplantation, dates to the 17th century with stumbling attempts to use animal blood for transfusions. By the 20th century, surgeons were attempting transplants of organs from baboons into humans, notably Baby Fae, a dying infant, who lived 21 days with a baboon heart.
With no lasting success and much public uproar, scientists turned from primates to pigs, tinkering with their genes to bridge the species gap.
Pigs have advantages over monkeys and apes. They are produced for food, so using them for organs raises fewer ethical concerns. Pigs have large litters, short gestation periods and organs comparable to those of humans.
Pig heart valves also have been used successfully for decades in humans. The blood thinner heparin is derived from pig intestines. Pig skin grafts are used on burns, and Chinese surgeons have used pig corneas to restore sight.
Kidney ready for transplantation from a live donor Image credit: wikimedia commons
In the NYU case, researchers kept a deceased woman's body on a ventilator after her family agreed to the experiment. The woman had wished to donate her organs, but they weren't suitable for traditional donation.
'Good could come from this'
The family felt "there was a possibility that some good could come from this gift," Montgomery said.
Montgomery himself received a transplant three years ago, a human heart from a donor with hepatitis C because he was willing to take any organ.
"I was one of those people lying in an ICU waiting and not knowing whether an organ was going to come in time," he said.
Several biotech companies are in the running to develop suitable pig organs for transplant to help ease the human organ shortage. More than 90,000 people in the U.S. are in line for kidney transplants. Every day, 12 die while waiting.
The advance is a win for Revivicor, a subsidiary of United Therapeutics, the company that engineered the pig and its cousins, a herd of 100 raised in tightly controlled conditions at a facility in Iowa.
The pigs lack a gene that produces alpha-gal, the sugar that provokes an immediate attack from the human immune system.
In December, the Food and Drug Administration approved the gene alteration in the Revivicor pigs as safe for human food consumption and medicine.
But the FDA said developers would need to submit more paperwork before pig organs could be transplanted into living humans.
"This is an important step forward in realizing the promise of xenotransplantation, which will save thousands of lives each year in the not-too-distant future," said United Therapeutics CEO Martine Rothblatt in a statement.
Experts say tests on nonhuman primates and last month's experiment with a human body pave the way for the first experimental pig kidney or heart transplants in living people in the next several years.
Raising pigs to be organ donors feels wrong to some people, but it may grow more acceptable if concerns about animal welfare can be addressed, said Karen Maschke, a research scholar at the Hastings Center, who will help develop ethics and policy recommendations for the first clinical trials under a grant from the National Institutes of Health.
"The other issue is going to be: Should we be doing this just because we can?" Maschke said. (VOA/RN)
Keywords: Transplant, Pig, Human, Kidney, FDA
- 10 Reasons why you should stop eating Chicken - NewsGram ... ›
- Do you Know? A Park in Thailand represents the Hell of Buddhism ... ›
- Bursting Myths About Hair Transplantation - NewsGram - Lens to ... ›
- A Drug That Can Potentially Cure Hair Loss - NewsGram - Lens to ... ›
- Adopting Mediterranean Diet may Help Kidney Patients Post ... ›
Kishu Inu and Dogelon Mars are some of the more popular canine coins in recent months. Their popularity is demonstrated by the vast amount of trading volume that these cryptocurrencies receive.
At the time of writing, Kishu Inu has a trading volume exceeding $10 million and Dogelon Mars has an even larger trading volume that surpasses $30 million.
An interesting difference between the two canine cryptos is that Dogelon Mars actually has no White Paper; its tokenomics are available in the frequently asked question (FAQ) section of their website.
HUH Token is a new exciting cryptocurrency that has just released its White Paper for the public to examine. HUH Token is still in presale, but the window to become a holder before any potential price increase is quickly disappearing.
HUH Token has introduced an incentive for those who are contemplating joining their growing community. Those who purchase HUH Token during the presale will receive 25% more tokens than if they bought afterwards.
This amount is increased to 35% if that deposit is worth more than $1000, an exciting opportunity to accumulate tokens ahead of the curve.
Dogelon Mars, while unconventionally, has released its tokenomic information in its FAQs. The total supply of Dogelon Mars is one quadrillion. Upon release, they had burned 50% of their tokens in a wallet dedicated to Vitalik Buterin to ensure fair distribution. The remaining 50% was provided as liquidity on Ether and Uniswap. The idea was to provide the community with the resources to help those who have been victims of rug pulls and scams.
Kishu Inu did release a full White Paper and their information is available to everyone. In their white paper, they outline their project and what they would like to accomplish moving forward. Their three fundamental principles included are transparency and community, trust and longevity.
Kishu Inu has a maximum supply of 100 quadrillion, and the amount is very high so that their holders can benefit from their reward system. Kishu Inu grants 2% of each transaction made to all Kishu Inu wallet holders. The higher the trading volume, the more rewards are disbursed.
Also Read: Use These Tools to Calculate Your Crypto Tax
HUH Token have only recently released their whitepaper, and many who have been excited to see the project develop will be taking a close look. HUH Token have coined the term ‘Utimeme’ as a way to describe their token, taking both aspects from a meme and utility token. HUH Token utilises a compound growth effect for those who hold onto their crypto.
Much like Kishu Inu in their whitepaper, the more trade volume that involves HUH Token the more of the token will be redistributed to all HUH Token wallets. The amount depends on the amount of HUH Token someone owns. Therefore if someone owns 0.5% of the supply, then 0.5% of HUH rewards will be reflected into their account. This ensures that fair distribution is achieved as the reward reflects the amount of faith placed in the project.
Additionally, HUH Token are introducing their own social platform. It will be known as MetHUH, and users can generate sentiment tokens that can then be traded for HUH Tokens. Individuals will sign up as either an influencer or as a user.
Influencers will post content and users will interact with that content. A wallet must be connected in order to claim tokens and rewards. The White Paper contains a vast amount of information regarding MetHUH, and it is encouraged that those wanting to become a part of their community read it.
This, and much more, are included in the White Paper and a common theme is apparent throughout. HUH Token has provided a large number of ways for individuals to grow their wealth over time. The reward systems are abundant, the opportunities to generate more HUH Token and even BNB rewards through a referral system are enough to create additional income.
Kishu Inu and Dogelon Mars have shown their prowess as meme cryptos on the market. The information on their respective White Papers, and lack thereof in Dogelon Mars’s case, seems to pale compared to the comprehensive explanation in HUH Token’s White Paper. As this is one of the last opportunities to join HUH Token’s presale, anyone who has been enticed by what their White Paper has to offer should consider joining sooner rather than later.
Follow HUH Token on their Socials before they Launch:
It’s also great to note that Shiba Inu made a triumphant crypto market return this week and the reign of the dog continues though with HUH Token’s White Paper release it could see the ‘Utimeme’ token break out of the atmosphere on its December 6th launch and surpass Shiba Inu for altcoin supremacy.
Here are some of my highlights of HUH Token’s White Paper release and why me and you should be excited for HUH Token’s launch on Monday!
As well as a look at why Shiba Inu might have rose back to the top dog spot this week.
Follow NewsGram on Twitter to stay updated about the World news.
Kid, You Might Just Need HUH Token.
HUH Token’s White Paper release could just be December’s utter-most crypto news, or at least a very close second to HUH Token’s December 6th launch… though as the White Paper was released to today the already iconic HUH Token dropped the mic.
And it’s one-hell-of-a-read and it’s true that the brilliance is in the detail.
One aspect of HUH Token’s White Paper that stood out to me and appears to have become a noteworthy point for other crypto lovers is that HUH Token want to facilitate access to technology, and this could see the future of cryptocurrency in its infancy.
Also Read: The Great Indian Crypto Circus
Inspired by Shiba Inu’s harnessing of influence into currency, HUH Token have seen the potentially that all can create content and be rewarded from this by HUH Token and by doing this, countries could see a healthier financial economy.
Though, one of the ways that HUH Token are endeavouring to build such an equilibrium inside of their MetaHUH for its holders is to use Smart Contracts, which could enhance static reward systems that incentivises HUH Token holders to hold until gold.
These smart contracts are supposed to help protect HUH Token holders from market fluctuations and that’s something unparalleled on the market.
This is also backed up by HUH Token’s use of a multichain (Ethereum and Binance) as well it’s ‘Utimeme’ power.
HUH Token’s Utimeme brilliance will allow the influence of meme coins to be harnessed for usability as well, and that’s one of the reasons that could see HUH Token surpass Shiba Inu when it’s released on December 6th.
The Early Bird Catches the Worm
Today is exciting and not simply because it’s a Friday, but because HUH Token released their White Paper, and this coming Monday will see the launch of one of the most awaited cryptocurrencies of 2021.
With some brain tingling ideas and aims from HUH Token it’s no wonder that its presale holders would have skyrocketed today, and you could be one of them who benefits from a 35% bonus on top of a $1000 deposit with HUH Token.
Though, it’s advised that you take a look around and read some other White Papers of other cryptocurrencies to make sure you’re becoming a holder of a crypto that serves you.
Follow HUH Token on their Socials before they launch:
(Disclaimer: This article is sponsored and includes some commercial links.)
Not only this but Shiba Inu’s mastery of the altcoin world could be coming to an end on HUH Token’s December 6th release if the aims, goals and technology in the White Paper are anything to go by.
Also, how Shiba Inu have managed to harness the power of influence.
But taking a peak behind the White Paper could offer you many wonders and grant the light that HUH Token deserves.
The Influence of Cute!
Shiba Inu harnessed something in August 2020 and that was the power of influence, which spawned many other dog-based and meme coins from its tremendous success.
Shiba Inu managed to demonstrate to seasoned crypto investors and whale cryptocurrencies that the power of the people is strong and it’s something that could be harnessed to propel not only the crypto world but the individual wins of crypto holders as well.
And so was born the creation of influence-based cryptocurrency and it’s given birth to the kind of innovation that whale cryptocurrencies just might not be able to conjure-up anymore.
It’s because of altcoins like Shiba Inu that more and more people are cottoning on the exponential possibilities that cryptocurrency can offer, not just to you, but to the world as a whole… and because of this pioneering spirit of Shiba Inu, Dogecoin and other altcoins presented emerging currencies like HUH Token with a rare opportunity that their White Paper shows they’re willing to undertake.
HUH? The White Wizard.
HUH Token’s White Paper release today saw the December 6th launching cryptocurrency hit new heights because of its pioneering ways in both technology and holder-centric notions.
The lengthy and heavily detailed White Paper explains what is in hold of the future of HUH Token, HUH Nation and MetHUH.
HUH Token intend to use influence and content as currency and for that reason could possibly be one of the biggest altcoins on the market, because like Shiba Inu, HUH Token see the power of the people and what that can do for them and their communities.
With many wonderfully amazing adages to the cryptocurrency world, HUH Token is pioneering multichain technology across both Ethereum and Binance blockchains but also redistributing rewards and returns through reflection technology.
The reward system another area where HUH Token could be unique to the cryptocurrency world because it offers four distinct routes to achieving reward receival.
They are as follows and you might want to peel your eyes for this one and makes sure you’re not on the edge of your seats… there might be no where else to go from that point:
Rewards will be sent to you in BNB (Binance Coin) and sent to a relevant wallet.
Claim Reward in Token of Choice
Your reward could be in ETH, USDT, MATIC and Others.
Claim to Another Wallet
Holders can use different wallets.
Claim As a Mix of The Above Two
Allows reward holders to gift any amount to another HUH holder.
(With this HUH Token hope to incentivise the gift of giving and strengthen HUH Token’s community)
The Influence of the Future
Influence and content are everything in a technological age and for that reason HUH Token and Shiba Inu spotted a niche to be harnessed and spread through holders of their cryptocurrencies and beyond.
The ever-growing cryptocurrency worlds of Shiba Inu and HUH Token are heading for the stratosphere, and you could be a long for the ride.
Be sure to do you research and read Shiba’s website and HUH Token’s White Paper before its launch on December 6th.
if HUH Token’s White Paper is too good to resist then you could benefit from a 35% presale top up on a $1000 deposit, but that bonus won’t be there for long.
Follow HUH Token on their Socials before they launch:
(Disclaimer: This article is sponsored and includes some commercial links.)