Tuesday January 21, 2020
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Pollution can Cause Heart Attack, Adverse Impact on Reproductive Capabilities of Men

Under PHE, people are supposed to stay indoor

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Pollution, Heart Attack, Men
It is a serious concern that a Public Health Emergency (PHE) has been declared. Pixabay

With pollution rising to severe levels in the national capital, doctors have warned of a number of ill-effects on the health of the people, ranging from heart attack to adverse impact on reproductive capabilities of men.

Doctors warned the people of Delhi against going outside without wearing anti-pollution masks and asked them to use air-purifiers even inside their houses to tackle the impact of pollution on human health.

“It is a serious concern that a Public Health Emergency (PHE) has been declared. Under PHE, people are supposed to stay indoor. Even inside their homes, people should use masks or air-purifiers. The high level of pollution may result in heart attack, paralysis or even sudden deaths which we have seen last year,” said K.K. Agarwal, President, Confederation of Medical Associations of Asia and Oceania.

“So my advice would be that stay indoor, use air purifiers and masks to further provide protection against pollution,” said Agarwal, a former head of the Indian Medical Association (IMA).

Pollution, Heart Attack, Men
Doctors warned the people of Delhi against going outside without wearing anti-pollution masks and asked them to use air-purifiers even inside their houses to tackle the impact of pollution on human health. Pixabay

Apart from the deadly effects of pollution, the doctors also warned people against the dangerous impact of pollution on the reproductive abilities of the human body as they claim that PM10 particles could affect the quality of sperm among the males.

“PM10 particles have a tendency to increase the concentration of free radicals in the bloodstream which in turn affects the quality of sperm among males. Also, the presence of heavy metals like cadmium, mercury and lead has severe consequences on the life of sperm and the effect can be seen for over 90 days.

“Important factors like sperm motility and concentration are duly affected, which determines a pregnancy,” Arvind Vaid, Gynaecologist and IVF expert at Indira IVF Hospital, told IANS.

The Indian Medical Association said the number of patients suffering from pollution related ailments is increasing every day.

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“With increasing pollution in and around Delhi, public health has taken a toll. With high levels of pollutants and the rise in levels of particulate matter (PM2.5 & PM10) in the last week, more and more number of patients are turning up with various health ailments,” IMA spokesperson Narender Saini said.

Considering the steep rise in the pollution levels, the Environment Pollution (Prevention and Control) Authority (EPCA) on Friday asked the governments of Delhi, Haryana, Uttar Pradesh and Rajasthan to issue advisories asking the public to minimise exposure to the surroundings and take other measures to curb the challenging levels of pollution.

Delhi has announced closure of all schools till November 5 and other NCR cities may also follow suit. (IANS)

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Males Have Higher Risk of Suffering from Cancer: Study

Researchers explain why cancer risk is higher in males

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Cancer
DNA differences between men and women may explain why cancer risk is higher in males. Pixabay

DNA differences between men and women may explain why cancer risk is higher in males, according to a new study.

In findings published in the Journal of the National Cancer Institute, researchers have reported that loss of function in certain genes of the sex-determining Y chromosome, which is present only in men, may cause them to have an elevated risk for cancer.

Using data from 9,000 individuals, the researchers studied Y-chromosome gene function in patients with various types of cancer. The findings showed that cancer risk increases with loss of function of six key Y-chromosome genes in various types of cells.

“Recent studies have shown that complete loss of the Y chromosome, which is essential to foetal sex differentiation, occurs, with aging, in the cells of some men,” said study author Juan Ramon Gonzalez from Barcelona Institute for Global Health in Spain.

Cancer DNA
Suppression of the Y chromosome can occur as a result of loss of function in the chromosome. Pixabay

“Although the loss of the Y chromosome has previously been associated with higher incidence of cancer, the causes of this association are poorly understood,” Gonzalez added.

These six Y-chromosome genes are involved in cell-cycle regulation, the failure of which can lead to tumour development.

According to the study, understanding the biological differences between men and women in cancer is crucial for the development of personalised lines of treatment and prevention.

“Men are not only at higher risk of cancer than women, they also face a worse prognosis. In fact, these differences partially account for the lower life expectancy of men,” Gonzalez added.

According to the researchers, although men may be more exposed to carcinogens due to the type of work they do and at higher risk because they are less likely to consult a doctor, the study has shown that there are also biological factors that increase cancer risk among men.

“In fact, it seems that one of these factors can be found in the Y chromosome, the very essence of maleness,” said study lead author Alejandro Caceres.

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Suppression of the Y chromosome can occur as a result of loss of function in the chromosome, which would explain previous findings, or as a result of other mechanisms mediated by the chemical (epigenetic) inactivation of the same regions, the research said.

“Certain environmental exposures, for example to tobacco or other harmful substances, could affect chromosome function and lead to epigenetic modifications,” Gonzalez said. (IANS)