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Prenatal Exposure to Plastic Chemical may Reduce Cognitive Skills

As the mPFC is crucial for high-level cognitive functions, reduced cognitive flexibility is observed in developmental disorders such as autism

Prenatal or early exposure of your kids to a plastic chemical may harm brain development as well as reduce cognitive function, a study says.

Phthalates — chemicals that belong to the same class as Bisphenol A (BPA) and used in food packaging and processing materials — can potentially interfere with hormones important for the developing brain.

The study by researchers including Janice Juraska, from the University of Illinois in the US, showed that rats’ prenatal and early exposure to phthalates was associated with smaller medial prefrontal cortex (mPFC) — brain region responsible for deep and dreamless sleep.

They also performed poorly on an attention-switching task than those not exposed to the chemicals early in life.

As the mPFC is crucial for high-level cognitive functions, reduced cognitive flexibility is observed in developmental disorders such as autism
As the mPFC is crucial for high-level cognitive functions, reduced cognitive flexibility is observed in developmental disorders such as autism. Pixabay

The findings, published in Journal of Neuroscience, showed that perinatal phthalate exposure resulted in a reduction in neuron number, synapse number, size of the mPFC and a deficit in cognitive flexibility for both male and female adult offspring of these rats.

As the mPFC is crucial for high-level cognitive functions, reduced cognitive flexibility is observed in developmental disorders such as autism.

Also Read: thyroid Dysfunction May Lead to Diabetes During Pregnancy

The results show that perinatal phthalate exposure can have long-term effects on the cortex and behaviour of both male and female rats.

The findings are important as humans may be regularly exposed to a variety of phthalates, which are endocrine-disrupting chemicals, the researchers warned. (IANS)

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