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Prevention of 3 lakh diabetes cases possible by cutting sugar in fizzy drinks: Lancet

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Washington: A significant study revealed that by cutting sugar in sweetened drinks by 40 percent, over three lakh obesity-related Type 2 diabetes can be prevented.

An average reduction in energy intake of 38.4 kcal (calories) per day by the end of the fifth year will lead to an average body weight decrease of 1.20 kg in adults, leading to a reduction in overweight and obese adults by approximately 0.5 million and 1.0 million, respectively, researchers have found.

This would, in turn, prevent 274,000-309,000 obesity-related Type 2 diabetes over the next two decades.

If fruit juices were excluded from sugar-sweetened beverages (SSBs), the corresponding reduction in energy intake and body weight would be 31.0 kcal/day and 0.96 kg, respectively.

“This would result in a 0.3 million cases reduction in overweight and a 0.8 million cases reduction in obesity, which would, in turn, prevent around 221,000-250,000 diabetes cases over two decades,” the study noted.

The study, published in The Lancet Diabetes and Endocrinology journal, was led by Professor Graham MacGregor, who chairs the Action for Sugar group.

The impact was greater in adolescents, young adults and individuals from low-income families who consume more sugary drinks.

According to the authors, the strategy, if adopted would lead to an extensive reduction in energy intake from sugar-sweetened beverages and could, therefore, lower the predominance of overweight, obesity, and Type 2 diabetes in the long term.

“The findings provide strong support for the implementation of the proposed strategy,” they added.

They conclude that “individuals should also reduce their consumption of sugar-sweetened beverages in the long term, but this can be difficult because of the advertising power of industry”.

“Our proposed strategy provides an innovative and practical way to gradually reduce energy intake from sugar-sweetened beverages and its combination with other strategies, including a tax on sugar-sweetened beverages, would produce a more powerful effect,” they noted.

Dr Tim Lobstein, director of Policy, World Obesity Federation London wrote in a linked comment piece that the study has proved to be extremely essential to policymakers. (IANS)

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Common BP Drug May Prevent Onset Of Type 1 Diabetes

For the study, published in the Journal of Clinical Investigation, the team used a supercomputer, on the lab bench, in mice, and in humans

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Type 1 Diabetes

A drug commonly used to control high blood pressure may be also effective in preventing the onset of Type 1 diabetes in up to 60 percent of those at risk, researchers say.

The drug, methyldopa, has been used for over 50 years to treat high blood pressure in pregnant women and children and is also on the World Health Organization’s list of essential drugs.

Methyldopa was found to block a molecule called DQ8 — found in some 60 percent at the risk of getting Type 1 diabetes — which significantly increases the chance of getting the disease.

Blocking specifically the DQ8 molecule could also block the onset of the disease, the study found.

 

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“This is the first personalized treatment for Type 1 diabetes prevention,” said Aaron Michels, Associate Professor of medicine at University of Colorado – Anschutz.

“With this drug, we can potentially prevent up to 60 percent of Type 1 diabetes in those at the risk for the disease. This is very significant development,” Michels added.

Type 1 Diabetes

For the study, published in the Journal of Clinical Investigation, the team used a supercomputer, on the lab bench, in mice, and in humans.

They found that methyldopa not only blocked DQ8, but it did not also harm the immune function of other cells like many immunosuppressant drugs do.

ALSO READ: Diabetes can hamper your reproductive health

“We can now predict with almost 100 percent accuracy who is likely to get Type 1 diabetes. The goal, with this drug, is to delay or prevent the onset of the disease among those at risk,” Michels said.

The drug is taken orally, three times a day.

Besides, diabetes, the same approach of blocking specific molecules can be used in other autoimmune diseases such as rheumatoid arthritis, coeliac disease, multiple sclerosis, systemic lupus erythematosus and others, the researchers noted. (IANS)

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Night Shifts May Raise Risk Of Diabetes

For the study, published in the journal Diabetes Care, the team examined data from more than 270,000 people, including 70,000 who provided in-depth lifetime employment information and a sub-group of more than 44,000 for whom genetic data were available

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