Sunday February 25, 2018

Just in! Like Computer Software, Scientists can now Programme Cells in your Body to Fight Diseases!

Scientists found that RNA which is produced abundantly by humans, plants and animals can be genetically engineered to allow scientists to programme cells with specific commands

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Programme cells
Scientists have found that cells can be programmed with pre-defined RNA commands, in the manner of a computer's microprocessor VOA
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London, September 19, 2017 : A new technique can help programme cells like a computer to fight cancer, influenza, and other serious conditions, suggests new research.

A common molecule — ribonucleic acid (RNA), which is produced abundantly by humans, plants and animals — can be genetically engineered to allow scientists to programme cells, said the study published in the journal Nucleic Acids Research.

RNAs carry information between protein and DNA in cells, and the research proved that these molecules can be produced and organised into tailor-made sequences of commands — similar to codes for computer software — which feed specific instructions into cells, programming them to do what we want.

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Cells have the capacity to process and respond to instructions and codes inputted into their main system, said lead researcher Alfonso Jaramillo, Professor at University of Warwick in Britain.

Similar to software running on a computer, or apps on a mobile device, many different RNA sequences could be created to empower cells with a ‘Virtual Machine’, able to interpret a universal RNA language, and to perform specific actions to address different diseases or problems, the study said.

This will allow a novel type of personalised and efficient healthcare, allowing us to ‘download’ a sequence of actions into cells, instructing them to execute complex decisions encoded in the RNA.

The researchers made their invention by first modelling all possible RNA sequence interactions on a computer, and then constructing the DNA encoding the optimal RNA designs, to be validated on bacteria cells in the laboratory.

After inducing the bacterial cells to produce the genetically engineered RNA sequences, the researchers observed that they had altered the gene expression of the cells according to the RNA programme — demonstrating that cells can be programmed with pre-defined RNA commands, in the manner of a computer’s microprocessor.

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“The capabilities of RNA molecules to interact in a predictable manner, and with alternative conformations, has allowed us to engineer networks of molecular switches that could be made to process arbitrary orders encoded in RNA,” Jaramillo said.

As well as fighting disease and injury in humans, scientists could harness this technique to control plant cells and reverse environmental and agricultural issues, making plants more resilient to disease and pests.

“Throughout last year, my group has been developing methodologies to enable RNA sensing the environment, perform arithmetic computations and control gene expression without relying on proteins, which makes the system universal across all living kingdoms,” Jaramillo said.

“The cells could read the RNA ‘software’ to perform the encoded tasks, which could make the cells detect abnormal states, infections, or trigger developmental programmes,” he added.  (IANS)

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Artificial Intelligence Poses Risks of Misuse by Hackers: Researchers

The report makes a series of recommendations including regulating AI as a dual-use military/commercial technology

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There are many good uses of AI, but it can be misused too.
There are many good uses of AI, but it can be misused too.
  • Artificial Intelligence (AI) poses risk of hackers
  • AI uses computer system to do daily activities
  • AI uses many computer systems which can be misused by hackers

Rapid advances in artificial intelligence are raising risks that malicious users will soon exploit the technology to mount automated hacking attacks, cause driverless car crashes or turn commercial drones into targeted weapons, a new report warns.

The study, published on Wednesday by 25 technical and public policy researchers from Cambridge, Oxford and Yale universities along with privacy and military experts, sounded the alarm for the potential misuse of AI by rogue states, criminals and lone-wolf attackers.

AI can causes risk of hackers. pixabay
AI can cause risk of hackers. Pixabay

The researchers said the malicious use of AI poses imminent threats to digital, physical and political security by allowing for large-scale, finely targeted, highly efficient attacks. The study focuses on plausible developments within five years.

“We all agree there are a lot of positive applications of AI,” Miles Brundage, a research fellow at Oxford’s Future of Humanity Institute. “There was a gap in the literature around the issue of malicious use.”

Also Read: Indian Railways to use artificial intelligence

Artificial intelligence, or AI, involves using computers to perform tasks normally requiring human intelligence, such as making decisions or recognizing text, speech or visual images.

It is considered a powerful force for unlocking all manner of technical possibilities but has become a focus of strident debate over whether the massive automation it enables could result in widespread unemployment and other social dislocations.

AI is a powerful way of unlocking all technical mannerisms.
AI is a powerful way of unlocking all technical mannerisms.

The 98-page paper cautions that the cost of attacks may be lowered by the use of AI to complete tasks that would otherwise require human labour and expertise. New attacks may arise that would be impractical for humans alone to develop or which exploit the vulnerabilities of AI systems themselves.

It reviews a growing body of academic research about the security risks posed by AI and calls on governments and policy and technical experts to collaborate and defuse these dangers.

The researchers detail the power of AI to generate synthetic images, text and audio to impersonate others online, in order to sway public opinion, noting the threat that authoritarian regimes could deploy such technology.

Also Read: Artificial Intelligence has the potential to increase India’s annual growth

The report makes a series of recommendations including regulating AI as a dual-use military/commercial technology.

Artificial Intelligence is used to read text and images. Wikimedia Commons
Artificial Intelligence is used to read text and images. Wikimedia Commons

It also asks questions about whether academics and others should rein in what they publish or disclose about new developments in AI until other experts in the field have a chance to study and react to potential dangers they might pose.

“We ultimately ended up with a lot more questions than answers,” Brundage said. VOA