Monday January 22, 2018

Progression of Parkinson disease could be slowed with exercise

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Progression of Parkinson disease could be slowed with exercise
Progression of Parkinson disease could be slowed with exercise. wikimedia commons
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New York, Dec 23, 2017: Exercise can stop accumulation of a harmful protein which is believed to play a central role in the brain cell death associated with Parkinson’s disease, new research has found.

Engaging in exercise on a running wheel can stop the accumulation of the neuronal protein alpha-synuclein in brain cells, showed the study published in the journal PLOS ONE.

Parkinson’s disease causes progressive loss of muscle control, trembling, stiffness, slowness and impaired balance.

“Our experiments show that exercise can get to the heart of the problem in Parkinson’s disease,” said one of the researchers Curt Freed, Professor at University of Colorado Anschutz Medical Campus in the US.

“People with Parkinson’s who exercise are likely able to keep their brain cells from dying,” Freed added.

The experiment was conducted in a mouse model of Parkinson’s, and the mice in the study, like humans, started to get Parkinson’s symptoms in mid-life. At 12 months of age, running wheels were put in their cages.

The researcehrs found that in the running mice, exercise increased brain and muscle expression of a key protective gene called DJ-1, compared to control transgenic animals which had locked running wheels.

Those rare humans born with a mutation in their DJ-1 gene are guaranteed to get severe Parkinson’s at a relatively young age.

The researchers tested mice that were missing the DJ-1 gene and discovered that their ability to run had severely declined, suggesting that the DJ-1 protein is required for normal movement.

“Our results indicate that exercise may slow the progression of Parkinson’s disease by turning on the protective gene DJ-1 and thereby preventing abnormal protein accumulation in brain,” Freed said.

He explained that his animal experiments had very real implications for humans.

Parkinson’s is a disease caused by the death of brain cells that make a critical chemical called dopamine. Without dopamine, voluntary movement is impossible. (IANS)

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Opt for these healthy habits for a healthy new year

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Opt for healthy living this New Year by following healthy habits.
Opt for healthy living this New Year by following healthy habits. wikimedia commons

New Delhi, Dec 27, 2017: As we get ready to welcome 2018, most of us also commit to being better versions of ourselves. Leading a healthier lifestyle usually tops the list, but it is also one of the toughest things to achieve.

To finally break that cycle of unfulfilled resolutions, commit to just a few healthy habits and cultivate them throughout the year. Stick with them for a few weeks, and you will start feeling so good that you will want to follow them for the rest of the year, says Dr Hariprasad, Ayurveda Expert at The Himalaya Drug Company. He recommends a four simple tips that you can incorporate this new year to finally become a new you.

Exercise daily: Promise yourself that you will spend a minimum of 40 minutes every day exercising. You don’t need to follow the same routine; just ensure that you work out every single day. This could be a great way to fulfill a second new year resolution of learning a new skill such as yoga or a fun dance form such as salsa. Exercising should be exciting, and something that you look forward to. Let it not become a chore. Simple forms of exercise go a long way in preventive care — they help reduce the risk of cardiovascular diseases and osteoporosis, alleviate depression and anxiety, and even boost mental alertness and confidence.

Get enough sleep: The function of sleep is to not only relax the body, but also rest and restore the mind. It is necessary to heal and repair your heart and blood vessels. Ongoing sleep deficiency has been linked to an increased risk of various health issues that affect the heart as well as kidney, and also lead to high blood pressure, diabetes, and stroke. While you can function for a while without getting the necessary amount of sleep every day, it will eventually take a toll on you. Commit to sleeping a minimum of seven hours a day while aiming for eight, and you will feel yourself getting healthier and happier in a short amount of time.

Go natural: This year, make long-term wellness your goal instead of just trying to solve the problem at hand. As per Ayurveda texts and modern research, Guduchi can significantly help in preventive care, as it is a great promoter of immunity, aids in the fight against respiratory problems, and helps you get healthier. The herb is rich in antioxidants, and including it in your daily life can help you achieve better health. Adopting preventive care by consuming appropriate supplements can help reduce the chances of facing health problems altogether, rather than simply resorting to curative care when it arises.

Drink enough water: If you want to keep the doctor away, eight glasses of water a day is the way to do it. Water is the fuel your body runs on; it is necessary to keep your body functioning well. Drinking enough water can help you with weight loss, detoxification, digestion, beautiful skin and hair, and even easy bowel movement. Work at this goal throughout the day and it will keep getting easier. There are many ways to achieve this goal. Download an app, play a game, or set a reminder, but ensure you keep reaching for that glass of water and hit that two-litre goal.

Take control of your health and life by cultivating these simple habits to ensure that you make the most of this new year. (IANS)

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