Monday July 16, 2018

Prostate cancer, the second most common cause of cancer rises in rural India, according to experts

The rural masses need to be made aware of the treatment, drugs and technologies to combat the disease

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Prostate cancer
Sarcomatoid prostate carcinoma, abbreviated SPC. Wikimedia
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  • Prostate cancer is the sixth leading cause of cancer deaths among men worldwide
  • Experts claim, that the second most common cause of cancer, is rising in rural India 
  • The rural masses need to be made aware of the treatment, drugs and technologies to combat the disease.

New Delhi, September 22, 2017: Prostate cancer, the second most common cause of cancer and the sixth leading cause of cancer deaths among men worldwide, is rising in rural India, experts claim.

Cancer projection data shows that the number of cases will be doubled by 2020.

“Most of the metastatic prostate cancer cases are from rural areas. Therefore, it’s a challenge to government and doctors to decrease the risk factors and take prostate cancer risk in the rural areas very seriously,” P.N. Dogra, Professor and Head of Urology at AIIMS, said in a statement on Thursday.

The rural masses need to be made aware of the treatment, drugs and technologies to combat the disease.

“There is an urgent need to create awareness about prostate cancer threat amongst the rural population,” said Anup Kumar, Head (Department of Urology and Renal Transplant) at Safdarjung Hospital.

Also read: Abdominal fat drives cancer in postmenopausal women: Study

Safdarjung Hospital sees more than one lakh patients every month from all over the country.

Of these, 20 per cent are prostate cancer patients, in which 40 per cent are clinically localised, 30 per cent are locally advanced and 30 per cent are metastatic prostate cancer cases, Kumar said.

“Prostate cancer has become a major health problem globally during the last few decades. This disease is the second most common cause of cancer and the sixth leading cause of cancer death among men worldwide,” Dogra said.

According to the Population Based Cancer Registries in Delhi, the disease is the second most frequently diagnosed cancer among men in the national capital, accounting for about 6.78 per cent of all malignancies. (IANS)

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Omega-3 Fatty Acids in Diet can Prevent Cancer From Spreading

While dietary consumption of omega-3 fatty acids can lead to EDP-EAs, for those with cancer, something concentrated and fast acting is needed

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The results showed that the endocannabinoids slowed the growth of tumours and blood vessels, inhibited the cancer cells from migrating and caused cancer cell death.
The results showed that the endocannabinoids slowed the growth of tumours and blood vessels, inhibited the cancer cells from migrating and caused cancer cell death. (IANS)

While eating foods rich in omega-3 fatty acids, such as fatty fish, certain nuts and seeds, have been known to prevent heart diseases and arthritis, a new research, led by one of Indian-origin, showed that omega-3 fatty byproducts may also have anti-cancer effects.

The new study, led by Aditi Das from University of Illinois at Urbana-Champaign, US, showed that when the human body metabolises omega-3 fatty acids, it produces a class of molecules called endocannabinoid epoxides, or EDP-EAs. These have anti-inflammatory properties and can inhibit cancer’s growth and spread.

The EDP-EAs have similar properties to cannabinoids found in marijuana — but without the psychotropic effects — and they target the same receptor in the body that cannabis does.

“We have a built-in endocannabinoid system which is anti-inflammatory and pain-reducing. Now we see it is also anti-cancer, stopping the cells from proliferating or migrating,” said study leader Aditi Das from University of Illinois at Urbana-Champaign.

The higher concentrations of EDP-EAs did kill cancer cells, but not as effectively as other chemotherapeutic drugs on the market.
The higher concentrations of EDP-EAs did kill cancer cells, but not as effectively as other chemotherapeutic drugs on the market. Pixabay

“These molecules could address multiple problems: cancer, inflammation and pain,” Das added.

For the study, published in the Journal of Medicinal Chemistry, the team studied the effect of the molecule in mice with tumours of osteosarcoma — a bone cancer that is not only painful but also difficult to treat.

The results showed that the endocannabinoids slowed the growth of tumours and blood vessels, inhibited the cancer cells from migrating and caused cancer cell death.

The higher concentrations of EDP-EAs did kill cancer cells, but not as effectively as other chemotherapeutic drugs on the market. But, the compounds slowed tumour growth by inhibiting new blood vessels from forming to supply the tumour with nutrients. They also prevented interactions between the cells, and most significantly, they appeared to stop cancerous cells from migrating.

Also Read: Cancer-Causing Chemical Found In Odisha Fish Sample

While dietary consumption of omega-3 fatty acids can lead to EDP-EAs, for those with cancer, something concentrated and fast acting is needed, Das said.

“That’s where the endocannabinoid epoxide derivatives come into play – you could make a concentrated dose of the exact compound that’s most effective against the cancer. You could also mix this with other drugs such as chemotherapies,” she added. (IANS)