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Here comes a protein that can help them cut flab without high-intensity gym. Pixabay

In good news for couch potatoes, here comes a protein that can help them cut flab without high-intensity gym or even a brisk walk around the park. The catch is: It is not yet available as pills but occurs naturally in the body.

Called ‘Sestrin’, the protein might harness the benefits of a good workout without ever moving a muscle, say researchers from University of Michigan.


While studying a class of naturally-occurring protein called Sestrin, they found that it can mimic many of exercise’s effects in flies and mice.


The beneficial effects of Sestrin include more than just improved endurance and physical performance. Pixabay

The findings could eventually help scientists combat muscle wasting due to ageing and other causes.

Researchers have previously observed that Sestrin accumulates in muscle following exercise,” said Myungjin Kim, research assistant professor in the Department of Molecular & Integrative Physiology.

Kim, working with professor Jun Hee Lee and a team of researchers wanted to know more about the protein’s apparent link to exercise.

Taking advantage of Drosophila flies’ normal instinct to climb up and out of a test tube, their collaborators from Wayne State University in Detroit developed a kind of fly treadmill.

Using it, the team trained the flies for three weeks and compared the running and flying ability of normal flies with that of flies bred to lack the ability to make ‘Sestrin’.

“Flies can usually run around four to six hours at this point and the normal flies’ abilities improved over that period,” said Lee. “The flies without Sestrin did not improve with exercise”.

What’s more, when they overexpressed Sestrin in the muscles of normal flies, essentially maxing out their Sestrin levels, they found those flies had abilities above and beyond the trained flies, even without exercise.

In fact, flies with overexpressed Sestrin didn’t develop more endurance when exercised.

The beneficial effects of Sestrin include more than just improved endurance.


Called ‘Sestrin’, the protein might harness the benefits of a good workout without ever moving a muscle. Pixabay

Mice without Sestrin lacked the improved aerobic capacity, improved respiration and fat burning typically associated with exercise.

“We propose that Sestrin can coordinate these biological activities by turning on or off different metabolic pathways,” Lee said, adding that this kind of combined effect is important for producing exercise’s effects.

Lee also helped another collaborator, Pura Munoz-Cánoves of Pompeu Fabra University in Spain to demonstrate that muscle-specific ‘Sestrin’ can also help prevent atrophy in a muscle that’s immobilized, such as the type that occurs when a limb is in a cast for a long period of time.

Also Read- Avoid Storing Food in Aluminium Containers to Minimise Health Risks: Researchers

“This independent study again highlights that Sestrin alone is sufficient to produce many benefits of physical movement and exercise,” Lee said.

Could Sestrin supplements be on the horizon? Not quite, said Lee, adding that Sestrins are not small molecules, but “we are working to find small molecule modulators of Sestrin”. (IANS)


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Photo by Pixabay

Upcoming medical colleges in Uttar Pradesh will be named after saints and sages

The new medical colleges being opened in Uttar Pradesh will be named after saints and sages.

The state government has issued an order naming four district hospitals that are being converted into medical colleges.

These district hospitals are in Bijnor, Fatehpur, Chandauli, and Siddharth Nagar.

The Bijnor medical college has been named after Mahatma Vidur, a philosopher during the Mahabharata era and uncle of the Pandavas and Kauravas.

The Chandauli medical college has been named after Baba Keenaram, said to be the founder of the Aghori sect.

The Siddharth Nagar district hospital will be called Madhav Prasad Tripathi Medical College after the BJP politician from the region. Tripathi, popularly known as Madhav Babu, was also the first Uttar Pradesh BJP chief. He was elected MP from Domariyaganj in 1977, besides being two times Jan Sangh MLA and also a member of the UP legislative council.

The Fatehpur hospital has been named Amar Shaheed Jodha Singh Ataiya Thakur Dariyawn Singh Medical College, after the freedom fighter of 1857.

It is said that he was among the first to use Guerrilla warfare against the British, as taught by freedom fighter Tatya Tope.

Meanwhile, according to official sources, the medical college in Deoria will be named after Maharishi Devraha Baba and the medical college of Ghazipur in the name of Maharishi Vishwamitra.

The medical college of Mirzapur will be in the name of Maa Vindhyavasini, the medical college of Pratapgarh in the name of Dr. Sonelal Patel and the medical college of Etah will be named after Veerangana Avantibai Lodhi. (IANS/JB)

Keywords: Medical Colleges, Uttar Pradesh, Yogi Adityanath, India, Politics


Photo by Wikimedia Commons

Photo of Indian cricket team on the ground

Former Pakistan captain Inzamam-ul-Haq has picked India as the favourite to win the ongoing ICC Men's T20 World Cup in Oman and United Arab Emirates (UAE).

Inzamam feels that the Virat Kohli-led India have a greater chance of winning the trophy as the conditions in the Gulf nations are similar to the subcontinent, which makes India the most dangerous side in the event, according to Inzamam.

"In any tournament, it cannot be said for certain that a particular team will win' It's all about how much chance do they have of winning it. In my opinion, India have a greater chance than any other team of winning this tournament, especially in conditions like these. They have experienced T20 players as well," said Inzamam on his YouTube channel.

He said more than the Indian batters, the bowlers have a lot of experience of playing in the conditions. The Indian Premier League (IPL) was played recently in UAE and most of the Indian bowlers did well in that leg.

Inzy heaped praises on the Men in Blue for the confident manner in which they chased the target against Australia on a challenging track without needing Kohli's batting prowess.

"India played their warm-up fixture against Australia rather comfortably. On subcontinent pitches like these, India are the most dangerous T20 side in the world. Even today, if we see the 155 runs they chased down, they did not even need Virat Kohli to do so," he added.

Though he did not pick any favourite, Inzamam termed the India-Pakistan clash in the Super 12 on October 24 as the 'final before the final' and said the team winning it will go into the remaining matches high on morale,

"The match between India and Pakistan in the Super 12s is the final before the final. No match will be hyped as much as this one. Even in the 2017 Champions Trophy, India and Pakistan started and finished the tournament by facing each other, and both the matches felt like finals. The team winning that match will have their morale boosted and will also have 50 percent of pressure released from them," Inzamam added. (IANS/JB)

Keywords: India, Pakistan, Sports, ICC T20 World Cup, UAE.


Photo by Diana Akhmetianova on Unsplash

Skin problems like itchiness, dryness and flakiness can occur anytime if you're not moisturising your body enough.

Skin problems like itchiness, dryness and flakiness can occur anytime if you're not moisturising your body enough. It is commonly observed that while many people take their skincare routine seriously, a majority of them neglect to moisturise the body. It is important to keep in mind that timing matters a lot when it comes to applying moisturisers. Therefore, knowing the appropriate time to apply body lotion is essential.

Take a look at the ideal times to moisturise your body shared by Kimi Jain, Head of Retail, KIMRICA.

Morning
Moisturising the body in the morning sets your skin up to face countless irritants and environmental factors during the day. The skin is constantly exposed to harsh chemicals and pollutants when you're outside which is why using a protective and soothing moisturiser while going out is necessary. Kimirica's Five Elements Body Lotion comes with natural Aloe Vera extracts that act as a rich source of antioxidants and vitamins that helps protect your skin and provide a deep nourishing effect.

man in white crew neck t-shirt Moisturising the body in the morning sets your skin up to face countless irritants and environmental factors during the day. | Photo by The Creative Exchange on Unsplash

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