Monday February 19, 2018

Psychedelic drug helpful in curbing addiction to smoking: Study

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By NewsGram Staff Writer

Irrespective of the substance a person is addicted to, curbing an addiction is tough. Many people around the world are addicted to smoking and it is known to be a difficult habit to get rid of.

Many remedies such as Nicotine patches, cold turkey and chewing gum are tried by people globally with hardly any luck. Matthew Johnson, a behavioral pharmacologist at Johns Hopkins’ Behavioral Pharmacology Research Unit, Baltimore, suggests a different alternative – psilocybin – a drug that has been illegal for years, in most parts of Europe and North America.

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Psilocybin is a naturally occurring psychedelic and is the active ingredient of ‘magic mushrooms’. Illegal, but if psilocybin is given to smokers a few times, in a carefully controlled way, Johnson says that it can be remarkably effective in helping smokers kick the butt.

The use of psilocybin spread from the labs (for research) to drug counter culture which is why it was completely banned and even research was prohibited. Johnson believes that the drug has been off limits for the wrong reasons.

Now, the research by the team at John Hopkins under Matthew Johnson, has shown promising results. More than 460 psilocybin sessions have now been conducted at Johns Hopkins alone, ranging from investigating its use by cancer patients, to its effects on meditation. The Smoking Cessation programme, which has just finished its pilot stage, has attracted a lot of attention.

The volunteers are first prepared during the Cognitive Behaviour Therapy, and are asked to create their own mantra, which is like something they would like to remember later in life because it could be used as a motto, which would provide them with the necessary push towards achieving their goal and quitting the habit.

After CBT, they are given the drug in tablet form, and are allowed to self-administer. Post taking the pill, they are asked to lie down, plug in earphones and relax. They are not allowed to talk, but are asked to “go inward” into their thoughts and analyse.

[Research shows there’s a] 71% success rate for people who quit smoking just after they had a heart attack,” he explains. A heart attack would certainly qualify as a profound experience, but it’s not something you can go around triggering in people in order to stop them from smoking. Instead the aim is to use a powerful psychedelic trip to trigger a similar effect… an intense, abstract experience that changes the patient’s perspective. It’s this that the team refer to as a ‘mystical experience’,” Johnson was quoted.

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Air Pollution And Its Effects On Our Heath

Man is not just affected physically but his mental peace takes a toll too due to the increasing air pollution

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Stubble burning is one of the main reason behind heavy pollution in the Delhi and NCR region. Wikimedia Commons
  • Air pollution is a major concern nowadays and has major effects on one’s health
  • There are many toxic air pollutants in our environment which can cause severe health hazards
  • Health-related problems like asthma, headaches, nausea, etc. can be caused as an effect of air pollution

Air Pollution and their dreadful consequences are not some newly found phenomena of the new-found world. There have been instances of hazardous effects even in the past. The three major historic documentation, dating back to the middle of the 20th century, happened at Meuse Valley in Belgium, Donora in Pennsylvania, and London. The most gruesome of the three is the well-known London mishap that claimed over 4000 lives during the episode, due to temperature inversion and associated elevated levels of Air Pollution, and over 8000 lives in the subsequent period.

Air pollution can have severe effects on one's health.
Air pollution can have severe effects on one’s health.

Mankind is in a fast-paced race, always in the process of trying to outwit each other. The numerous developments born out of this race have brought along with them dreadful health consequences. Air Pollution is one such inadvertent yet a disregardful act by humans. The pollution does not begin only when you step out of your homes but is present within your safety havens itself.

According to the World Health Organization report in 2014, 92% of the world population was living in places where the air quality guidelines levels were not met. Outdoor Air Pollution was cited to be the cause of  3.7 million premature deaths in both cities and rural areas. Around 80% of those deaths were due to heart diseases and stroke, and the rest were due to respiratory illnesses and cancers due to exposure to fine particulate matter.

Air pollution can even cause risk of life.
Air pollution can even cause risk of life.
Air pollutants categories:

Air pollutants are categorized into two groups based on their impact, Criteria pollutants and Toxic air pollutants. Criteria pollutants include particulate matter (PM), ozone (O3), sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and lead (Pb). (defined by the United States Environmental Protection Agency in the Clean Air Act). These pollutants are present everywhere and cause health issues when present at significant ambient levels. In general, the criteria pollutants are regarded as the cause of most respiratory and cardiac issues.

Also Read: How exposure to air pollution in womb may shorten lifespan

Toxic air pollutants are also known as “hazardous air pollutants,” are substances that cause cancer or lead to other potential non-cancerous effects on the reproductive and neurological systems and have disastrous consequences in the development process. It is also assumed that there is no threshold level of exposure required to cause cancer. Meaning any amount of exposure to these toxic pollutants can lead to cancer.

At risk Populations:

In any geography, the already ailing and sick (pre-existing medical condition) population is more at risk for suffering from the ill effects of air pollution. Apart from this category, young children are the next at risk.

The reason for children being affected more is that they have higher breathing rates than adults. Therefore, they unknowingly inhale a lot more pollutants than an average adult. The potential for exposure is also increased with increased amount of time spent outdoors. The developing lungs of the young people have a limited metabolic capacity to placate toxicity.

Exposure to air pollutants can case cancer as well.
Exposure to air pollutants can cause cancer as well.

 

Air Pollution Respiratory Diseases:

The small particulate matter of the criteria pollutants has the capacity to reach the lowest portion of the lungs, where the gaseous exchange occurs. The larger particles get trapped in the nose and the medium- sized ones settle in the tracheobronchial region.

The effects of the settlement of these particles are upper and lower respiratory symptoms, asthma attacks, loss of quality living days, and restricted activities. Chronic exposure to particulate matter has also been associated with the development of chronic bronchitis- inflammation of the lining of the bronchial tubes. This condition presents as a cough with mucus.

Also Read: Neurologists say rising air pollution can cause stroke among adults

Lung Cancer:

It is a commonly known fact and an “ought to be stressed upon” fact that chronic exposure to polluted air can also lead to the cancer of the lungs.

Ozone’s effect:

Ozone, an oxidant gas that is poorly water-soluble, travels throughout the respiratory tract due to its nature of solubility. It reacts with the molecules on the surface of the lung and leads to pulmonary oedema, inflammation, and the destruction of epithelial cells that line the respiratory tract. Children who stay outdoors in high Ozone areas develop asthma. Some of the disastrous effects are permanent in nature.

Air pollution can harm you even when you are inside your own houses.
Air pollution can harm you even when you are inside your own houses.
Some more Criteria air pollutants:

When Carbon monoxide reacts with blood haemoglobin, it reduces the oxygen-carrying capacity of blood and hence can cause damage to the nervous system. It causes a headache, fatigue, dizziness, coma, respiratory failure, and eventually death.

Nitrogen dioxide is mostly an indoor air pollutant released due to the increasing use of gas stoves. Exposure to high levels of nitrogen dioxide can lead to respiratory distress with symptoms such as cough, shortness of breath, and tightness in the chest.

Air Pollution Cardiovascular Effects:

The above-mentioned actions of air pollutants in the respiratory tract can also affect the cardiovascular system. The inflammation in the breathing tract induces transient hypercoagulability (abnormal blood clotting), the progression of atherosclerosis, and propensity to plaque rupture, especially in people with coronary atheroma. Long-term exposure to Air Pollution can also speed up the atherogenesis process, heart rate invariability, and arrhythmia (irregular heartbeat). Some recent studies have also found a significant relationship between heart attack (Myocardial infarction) and exposure to polluted air.

Air Pollution in Reproductive and Child Health:

Long-term exposure to the air pollutants poses risks even to an unborn child. It causes Intrauterine growth restriction -low birth weight at term, intrauterine growth retardation, smaller fetus for gestational age etc.

Indoor Air Pollution :

Some of the major causes of indoor air pollution are indoor smoking and burning of fuels for cooking purposes, especially in the second and third world countries. The people in these countries cook and heat their homes with biomass fuels and coal. Thus the main noxious gas released is sulfur dioxide, that causes respiratory issues and eye irritation

 

In Delhi, air pollution is a major concern.
In Delhi, air pollution is a major concern.
Quality of life:

Man is not just affected physically but his mental peace takes a toll too when the feelings of insecurity and the perception of having to live in a hazardous environment take over. Severe annoyance, sleep disturbances, reduced the ability to concentrate, communicate or perform normal daily tasks also accompany the psychological stress issues.

Some of the issues are too massive to be controlled at an individual level but a resolution to change can, of course, make a significant impact. Individually we are just one drop of water but together we can make a big ocean.

Simple steps involve following the government regulations in your state regarding the upkeep of your vehicles, carpooling, avoiding the burning of coal, adequate ventilation of your homes to dilute the effect of indoor air pollutants among others.

Wish for a change? Be the change! Same Condition

Air Pollution Health Effects