Get subscribed to our newsletter
Get interesting updates to your email inbox.
The nasal spray contains a chemical that can inactivate the coronavirus spike protein, which was produced by researchers at the University of Helsinki in Finland. TriSb92, the novel molecule, has been demonstrated to protect against coronavirus infection for at least eight hours in cell cultures and animal trials, even in circumstances of high exposure risk.
In contrast to vaccination protection, TriSb92's action begins very immediately after it is given.
"In animal models, nasally delivered TriSb92 provided protection against infection in an exposure condition when all unprotected mice were affected," stated Anna Makela, a varsity postdoctoral researcher. The findings have not yet been subjected to peer review.
The TriSb92 molecule is based on a completely new technology technique for targeting biological agents that was created in Finland. The solution was used in the study to stop the spike protein on the surface of the SARS-CoV-2 virus from working.
"Targeting the TriSb92 molecule's inhibitory impact on a region of the coronavirus spike protein that is common to all variations," Makela stated.
Image showing how TriSb92 works.YLE/wikipedia
TriSb92 was able to stop the spread of SARS, the virus that attacked us in the early 2000s, in model viral tests.
"In other words, we may reasonably expect future varieties of SARS-CoV-2, and possibly even totally new coronaviruses, to be sensitive to it," Makela added.
The chemical might be used as a type of biological defence against coronavirus infection that is sprayed on the mucous membranes in the future if it is given as a nasal spray."
Also read: How Covid infection affects your liver?
These sorts of infection-prevention chemicals, or antiviral medications for that matter, cannot replace vaccinations in safeguarding the population against the coronavirus sickness," stated university Professor Kalle Saksela.
However, there is a pressing need for new ways to improve the protection offered by vaccinations. "TriSb92 may be beneficial to patients whose vaccination protection is limited due to a variety of factors. It may also help fully vaccinated persons when given before any setting with a high chance of exposure, depending on the epidemic condition "Saksela said. (IANS/PR)
(Keywords: TriSb92, SARS-CoV-2 virus, nasal spray, coronavirus infection, infection-prevention chemicals, antiviral medications)
New Delhi, Jan 12 (IANS): Leading Western experts believed a lab leak in Wuhan was the 'likely' origin of Covid but were silenced because it could cause harm to Chinese scientists, bombshell emails show, the Daily Mail reported. Sir Jeremy Farrar, who publicly denounced the theory as a 'conspiracy', had admitted in a private email in February 2020 that a 'likely explanation' was that the virus was man-made.
The then-UK government advisor said at the time he was '70:30 or 60:40' in favour of an accidental release versus natural origin, the report said. In the email, sent to American health chiefs Anthony Fauci and Francis Collins, Farrar said it was possible that Covid had been evolved from a Sars-like virus in the lab. He went on that this seemingly benign process may have 'accidentally created a virus primed for rapid transmission between humans'.
Also Read : Tissue culture lab at Kanha Shantivanam
But the British scientist was shut down by his counterparts in the US who warned that further debate about the origin of the virus could damage 'international harmony', the report said. He was told by other scientists with links to virus manipulation research that it could cause 'unnecessary harm to science in general and science in China in particular'.
Mike Farzan, the Harvard researcher who first discovered how the original Sars virus binds to human cells. National Cancer Institute / Unsplash
Farrar claimed in his emails that other respected scientists also believed the virus could not have emerged naturally. The names included professor Mike Farzan, the Harvard researcher who first discovered how the original Sars virus binds to human cells, the report said. Despite his concerns, Farrar went on to sign letters in The Lancet a fortnight later denouncing anyone who believed in the lab leak theory as bigoted. (IANS/SP)
(Keywords : western, experts, China, laboratory, leak, COVID, virus, accidental, debate, manipulation, research, science, scientists, Sars, transmission, human, American, British.)
- Covid vaccines' mixing considered safe & effective - NewsGram ... ›
- Long COVID Still A Risk With Omicron Despite Mild Illness ... ›
According to a new study done by academics at the University of Tennessee, up to 11% of Covid-19 users had liver co-morbidities.
During the course of the disease, 14% to 53% of people had higher levels of liver enzymes such alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Increased levels of liver enzymes may indicate that a person's liver has been damaged, at least briefly. Covid has resulted in significant liver damage in some cases. Swelling of the liver, jaundice (yellow discoloration of the eyes and urine), and failure of liver function tests are the most prevalent.
Also read: Covid to become a seasonal pandemic
Dr Shubham Vatsya, Consultant - Gastroenterology at Fortis Escorts Hospital in Faridabad, told IANS that nonspecific inflammation caused by Covid is fairly frequent in the liver and appears in numerous forms. "Covid infection can cause a wide spectrum of liver damage, some of which are entirely asymptomatic. It might result in jaundice or even liver failure "Dr. Jatin Agrawal, Associate Consultant, Gastroenterology, Max Hospital, Saket, added to the discussion.
Covid has resulted in significant liver damage in some cases. Swelling of the liver, jaundice (yellow discoloration of the eyes and urine), and failure of liver function tests are the most prevalent.
Covid infection can cause a wide spectrum of liver damage, some of which are entirely asymptomatic.Nature/wikipedia
Dr Shubham Vatsya, Consultant - Gastroenterology at Fortis Escorts Hospital in Faridabad, told IANS that nonspecific inflammation caused by Covid is fairly frequent in the liver and appears in numerous forms.
"Covid infection can cause a wide spectrum of liver damage, some of which are entirely asymptomatic. It might result in jaundice or even liver failure "Dr. Jatin Agrawal, Associate Consultant, Gastroenterology, Max Hospital, Saket, added to the discussion. While immunizations can lessen the severity of Covid infection, research on whether they can prevent liver impairment is "extremely sparse," according to him.
Also read: How masks prevent risks of Covid infection
Viruses can alter the liver's function in a number of ways, according to Agrawal. "One is due to the virus's direct effect on hepatocytes (liver's main functional cells) and cholangiocytes (bile duct epithelial cells) via the ACE2 receptor, while the other is due to medication interactions. The liver is affected by covid storm and sepsis "He expressed himself.
"Proper nutrition, intake of a high protein diet, which includes eggs, green leafy vegetables, paneer, it would help you maintain your immunity and it is also a very essential metabolite for the liver," Vatsya explained.
(Keywords: Covid Infection, University of Tennessee, Liver, immunizations, hepatocytes, cholangiocytes, ACE2 receptor, high protein diet, green leafy vegetables, paneer)
The Defence Ministry, which has conducted the first-ever digital survey and documentation of its lakhs of acres of its land holdings across the country, has now begun specialised training for capacity-building of technical personnel and officers of the Defence Estates Organisation, to protect its land from encroachment or other misuses, officials said. Modern survey technologies like Electronic Total Station (ETS) and Differential Global Positioning System (DGPS) were used in the survey, and to further speed up the process, drone and satellite imagery were leveraged for reliable, robust and time-bound outcomes.
"The entire exercise of survey of about 1.61 lakh acres of defence land inside cantonments and 16.17 lakh acres outside cantonments (total 17.78 lakh acres) survey has been completed. It is a remarkable achievement since, for the first time after independence, entire defence land has been surveyed by using latest survey technology and in a large number of pockets in association with the revenue authorities of various state governments. The magnitude of land holding, location of land in approximately 4,900 pockets across the country, inaccessible terrain in many places and association of various stakeholders makes this survey one of the largest land surveys in the country," the Defence Ministry said.
The Defence Ministry, which has conducted the first-ever digital survey and documentation of its lakhs of acres of its land holdings across the country. | Wikimedia Commons
For the first time, drone imagery-based technology was used for survey of lakhs of acres of defense land in Rajasthan. The entire area was surveyed with the help of the Surveyor General of India in a matter of weeks, which earlier used to take years. Besides this, satellite imagery-based survey was done for the first time for many defence land pockets, especially for certain pockets again measuring lakhs acres of defence land. 3D Modelling techniques for better visualisation of defence land in the hilly areas have also been introduced by utilising Digital Elevation Model (DEM) in association with Bhabha Atomic Research Centre (BARC).
As per the records maintained by Defence Estates Offices, the Ministry of Defence owns large tracts of land admeasuring about 17.99 lakh acres out of which approximately 1.61 lakh acres is situated within the 62 notified Cantonments and about 16.38 lakh acres are spread across many pockets outside the Cantonments. Out of 16.38 lakh acres, about 18,000 acres is either state hired land or is proposed for deletion from records on account of transfer to other government departments,
As per the records maintained by Defence Estates Offices, the Ministry of Defence owns large tracts of land admeasuring about 17.99 lakh acres. | Photo by Lukas Blazek on Unsplash
The magnitude and location of land holdings and association of various stakeholders make the management of defence land not an easy task to maintain, so the Ministry had decided to establish a Centre of Excellence for this purpose only. 'The Defence Minister, while inaugurating the Centre of Excellence during last month, exhorted the DGDE to continue to excel in the field survey and building capacity in using GIS based technologies.
The Centre of Excellence on Land Survey and GIS mapping has been established in NIDEM (National Institute of Defence Estates Management) for capacity building of defence estates officials in the field of latest survey technologies in association with premier institutes like the National Remote Sensing Centre and the National Institute for Geo-Informatics Science and Technology. The CoE aims to be an apex survey institution capable of imparting training of various levels to the officers of Central and state government departments. CoE also aims to use SLAM/GIS technologies in better land management & town planning processes, the ministry said. (IANS/ MBI)
(Keywords: Defence Ministry, land survey, magnitude, location, Science, technology, survey, digital, NIDEM, drone imagery-based technology)