Tuesday, March 2, 2021
Home Indian Diaspora Researchers find potential way to combat MERS virus

Researchers find potential way to combat MERS virus

news.indiaonline.in
news.indiaonline.in

New York: Researchers, including one of Indian-origin, have found molecules that shut down the activity of an enzyme essential to the Middle East Respiratory Syndrome (MERS) virus replication.

The virus is in the international spotlight again as South Korea faces the largest MERS outbreak outside the Middle East.

More than 2,800 people have been quarantined during the outbreak. The World Health Organisation (WHO) reported 27 deaths and 172 confirmed cases in its most recent update on June 22.

Professors Arun Ghosh and Andrew Mesecar from Purdue University in the US have been studying the virus and creating and testing molecular compounds that could lead to potential treatments since shortly after MERS was discovered.

“The team identified molecules that inhibit an enzyme essential to MERS virus replication and discovered a characteristic of the enzyme that is very different from other coronaviruses, the family of viruses to which MERS-CoV belongs,” Mesecar said. He added, “This enzyme is a prime target – an Achilles’ heel of the virus.”

The team was targeting an enzyme within the MERS virus called 3C-like protease, without which the virus cannot create more viruses to further an infection.

“We captured the protease’s atomic structure through this work, which provides the map to design potent new drugs to fight MERS,” said Mesecar.

The MERS virus emerged in 2012 and was mostly confined to the Middle East until 2014 when cases were identified in the US, Britain, France and Italy. Till date, 25 countries have reported cases, according to the WHO.

“It is a threat to public health and there currently is no treatment or vaccine. We continue to study the virus to improve our understanding of how it works and ways to prevent its spread.”

The study was published in the Journal of Biological Chemistry.

(IANS)

 

STAY CONNECTED

19,120FansLike
362FollowersFollow
1,773FollowersFollow

Most Popular

Mission Shakti Program: Girl Students In UP To Learn Self Defense

Under the ongoing Mission Shakti program, girl students in more than 40,000 upper primary schools will learn self-defense techniques between March 1 and 31. According...

AR Apps Powered By Apple App Store For Your Younger Ones

If you wish to aid the development of a scientific temper in your kids with the help of augmented reality (AR) on the occasion...

New AI Feature To Animate The Faces In Still Photos

 What if you could make your late grandfather in an old photo look up and smile at you? This and numerous other possibilities have...

Just One Vaccine Shot Reduces The Risk Of Being Hospitalized By Covid-19

Just one vaccine shot reduces the risk of being hospitalized by Covid-19 by more than 90 percent, according to new findings, Daily Mail reported....

Government of India Prepares a Master Plan To Promote Toy Industry

Guruprasad Mohapatra, Secretary for the Department for Promotion of Industry and Internal Trade, said that toys are of serious economic concern and a very...

Obstructive Sleep Apnea Linked To Lower Score Of Memory Skills

A disorder called obstructive sleep apnea that occurs when breathing is repeatedly interrupted during sleep is common in people with thinking and memory problems,...

How A Single Thought Or Argument Takes The Shape Of A Disease?

When we break the word 'disease', it comes through as 'dis' and 'ease' -- something that is not at ease. Anything which makes you...

Check Out New Courses For Journalism Field Offered By Google India

Data journalism, reverse visual search and mobile journalism are among the new courses that the Google News Initiative announced on Monday. The new courses are...

Recent Comments