Thursday, September 24, 2020
Home Lead Story Researchers Have Successfully Created Artificial Placenta

Researchers Have Successfully Created Artificial Placenta

Initial tests have already shown that the artificial placenta on the chip does in fact behave in a similar way to a natural placenta: small molecules are allowed to pass through, while large ones are held back, the researchers noted.

Using a high-resolution 3D printing process, Austrian researchers have succeeded in creating an artificial placenta barrier on a chip, a development that can be used to investigate important aspects of nutrient transport from the mother to the foetus.

The placenta ensures the exchange of important substances between the mother and her unborn child, whilst simultaneously blocking other substances from passing through.

“The transport of substances through biological membranes plays an important role in various areas of medicine,” said Aleksandr Ovsianikov, professor at the TU Wien university in Vienna.

“These include the blood-brain barrier, ingestion of food in the stomach and intestine, and also the placenta.”

This can help provide clarity on how the exchange of glucose between mother and child takes place. Wikimedia Commons
This can help provide clarity on how the exchange of glucose between mother and child takes place. Wikimedia Commons

Studies have shown that diseases such as diabetes and high blood pressure in the mother can affect the transport of substances to the foetus. Until now however, it has been almost impossible to investigate the way in which the many parameters involved interact in such cases.

Using the 3D printing made it possible to produce customised hydrogel membranes directly within microfluidic chips, which are then populated with placenta cells.

This can help provide clarity on how the exchange of glucose between mother and child takes place, the researchers said.

The novel chip consists of two areas — one represents the foetus, the other the mother. Using a specially developed femtosecond laser-based 3D printing process helped produce a partition between them — the artificial placenta membrane.

The high-resolution 3D printing involved a hydrogel with good biocompatibility.

Also Read: Obesity During Pregnancy May up Kid’s Risk of Epilepsy

“Based on the model of the natural placenta, we produce a surface with small, curved villi. The placenta cells can then colonise it, creating a barrier very similar to the natural placenta,” Ovsianikov explained.

Initial tests have already shown that the artificial placenta on the chip does in fact behave in a similar way to a natural placenta: small molecules are allowed to pass through, while large ones are held back, the researchers noted. (IANS)

STAY CONNECTED

19,143FansLike
362FollowersFollow
1,775FollowersFollow

Most Popular

Microsoft Study Shows Pandemic has Increased Feeling of Burnout Among Workers

If you've been feeling overwhelmed at work lately, you are not alone as a new Microsoft study has shown that the pandemic has increased...

Lower Zinc Levels in Blood Linked to Higher Death Risk in Covid Patients: Study

In a major study, researchers have found that having a lower level of zinc in the blood is associated with a poorer outcome in...

Time Magazine List of 100 Most Influential People: Ayushmann Khurrana Among 5 Indians

Indian actor Ayushmann Khurrana is in the Time magazine list of 100 Most Influential People this year. Follow NewsGram on LinkedIn to know what's happening...

Return to Usual Sexual Activity After Heart Attack for Long-Term Survival

Returning to usual levels of sexual activity within a few months after a heart attack is positively associated with long-term survival, say researchers. According to...

Researchers Find Potential New Drug Candidate Against Enterovirus

Some good news in the search for antiviral drugs for hard-to-treat diseases as researchers have identified a potential new drug candidate against enterovirus 71,...

Stroke Patients With Covid-19 Show Increased Inflammation, Death Rate: Researchers

Stroke patients who also have Covid-19 showed increased systemic inflammation, more serious stroke severity and a much higher rate of death, compared to stroke...

Playing Video Games in Childhood Can Improve Working Memory Years Later

In a good news to video game lovers, researchers have found that playing video games as a child can improve working memory years later. The...

Know the Negative Impact of Covid-19 Lockdown on Kids

Children, who appear at a relatively lower risk from Covid-19, are disproportionately harmed by precautions involved with lockdowns, warn researchers. Experts from Oxford University Hospitals...

Recent Comments